Excited to share our latest work on ALS neuroimmunology, published today in @NatureNeuro rdcu.be/fiFM0

Genetically altered astrocytes that express chimeric antigen receptors offer a promising immunotherapy system capable of clearing accumulations of amyloid-β in the brains of mice—a hallmark pathological feature of #AlzheimersDisease, according to a new study in Science. 📄: scim.ag/3NjPIfP #SciencePerspective: scim.ag/4rgI1oL

Congrats @DGateLab on having one of the Top 3 Episodes of Breakthroughs Podcast in 2025! If you haven't listened you can do so and learn more here; news.feinberg.northwestern.e…

Key to research success: ambition in vision, but pragmatism in execution. You must be guided by a long-term, ambitious goal that addresses a fundamental problem, rather than chasing incremental gains on established benchmarks. Yet, your progress should be grounded by tractable short-term metrics/tasks that force you to constantly make contact with reality.

We are proud to announce a collaboration with @ARC_Neuro at Northwestern University Feinberg School of Medicine to harness AI for rapid discovery and innovation in Alzheimer’s disease research. Using Lens, the Center and Tempus teams will work together to uncover genomic patterns that have the potential to advance the understanding of Alzheimer’s disease, investigate the gene and cell types affected, enable the development of new therapeutics, and accelerate the creation of novel clinical applications. Learn more: tempus.co/43EIlVJ

I am excited to present our new study out in @NatureMedicine where we discover a novel synaptic protein biomarker to predict if and when someone will get Alzheimer’s disease dementia. Part 2/3 from my PhD work in the @wysscoray lab. 🧵1/12 Full study 🔗: nature.com/articles/s41591-0…

The Gate lab is fortunate to have such a talented scientist like @TerryRSuk joining us soon. Check out his impressive work!

In brains of people immunized against Aβ, postmortem omics reveal microglial plaque clearing pathways. @NorthwesternU ow.ly/3cOl50VitbY

It’s quite an experience to have some of your favorite labs like ⁦@TheColonnaLab⁩ and ⁦@Haass_Lab⁩ comment on your lab’s research. Great reporting by Alzforum! alzforum.org/news/research-n…

This Northwestern Breakthroughs podcast nicely encapsulates our study. The host does a great job leading the discussion for the lay audience to digest our work. I hope this allows people to better understand the results and impact of this study. youtu.be/bZrdwGQ_Ok0

This video describes the findings from our recent study conducted at ⁦@ARC_Neuro⁩. In the video, lead author ⁦@LynnOlst⁩ and I discuss the findings and their implications for Alzheimer’s disease. youtu.be/pnRzktJRWAo

アルツハイマー病の治療は脳自身のクリーンアップクルーにあるかもしれません nipponese.news/ア�%…

Excited to share our latest @NatureMedicine study from our new center @ARC_Neuro! 🧠✨ Using spatial transcriptomics & scRNA-seq, we uncover how Aβ-targeting immunotherapies shape microglial responses in AD patient brains. A thread with our key findings is below! 🧵(1/15)

Spatial transcriptomics reveals distinct microglial mechanisms driving amyloid-β clearance in both passive and actively immunized #Alzheimer’s disease patients @NUFeinbergMed nature.com/articles/s41591-0…

More excellent work from the brilliant @LynnOlst. I’m a very proud PI today. More to come from @ARC_Neuro!

Big day today!

Excited to announce that we are recruiting at our new Neurogenomics Center at Northwestern! We are looking for passionate postdoc candidates to join our team. nature.com/naturecareers/job…

The team at Abrams Research Center on Neurogenomics, led by @DGateLab, is excited to explore their new lab! Using #ArtificialIntelligence, genetic research and global collaborations, they’re advancing Alzheimer’s disease research. #NMBetter