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Fighting Metabolic Diseases Through Immune Modulation 👉 t1p.de/4uebn How does the immune system influence metabolism? 💡 A new study from #HelmholtzMunich and #DZD uncovers a key link between the immune system and metabolism in the brain’s hypothalamic region. The researchers found that regulatory T cells (Tregs) not only regulate immunity but also support metabolic balance. The results open new perspectives on immune-based therapies as a promising approach for treating metabolic diseases, including #obesity and #Type2diabetes. @DanielLabMunich @MatthiasTschop @labs_mann @MPI_Biochem @DiabResearch @TU_Muenchen @LMU_Muenchen @NatureComms #Immunology #Metabolism #DiabetesResearch #ImmuneSystem #Metabolism #Hypothalamus #Inflammation #Therapy

Out today in @ScienceMagazine! We show that rising self-antigen levels during infection give self-reactive T cells an opportunity for enhanced TCR signalling. Regulatory T cells of matched specificity counteract this, thereby preventing autoimmunity. buff.ly/3EXaXQa

Excited about setting up a pipeline with machine learning for fiber typing and morphometric analyses of skeletal muscle. I'm impressed by how beautiful Immunofluorescence is - there's just something timeless about it! 🔬 Thanks, @DyarKen and #Taoyue for this great opportunity!

How cool is this? Michal Lipinski from @broadinstitute presenting stacked #Illumina spatial slides of the mouse brain with subcellular transcriptome resolution #AGBTGM

#WomenAtHelmholtzMunich 👏 #HelmholtzMunich is celebrating inspiring careers and female leadership, because #ScienceNeedsHer! 👉 Check out our website and learn more about #WomenInScience at Helmholtz Munich: t1p.de/mddsr 🌟 Get inspired by thoughts of some of our top female scientists! 🎙️ What advice would you give your younger self? 🗨️ “Surround yourself with inspiring people, delegate efficiently and learn how to say no.” - Prof. Eleftheria Zeggini, Director of the Institute of Translational Genomics 🎙️What would you change for future generations? 🗨️"I would create a future where origin, race, and background are not even thought of in the workplace. Instead, everyone would be valued and united in the scientific endeavor based solely on their commitment, passion, work quality, and ethics." - Prof. Maria-Elena Torres-Padilla, Director of the Institute for Epigenetics and Stem Cells 🎙️What advice would you give your younger self? 🗨️“Be yourself, follow your passion, be curious and ask bold questions. Trust the journey, foster team growth and diverse perspectives. Science is a marathon, not a sprint - enjoy growing along the way.” - Prof. Carolin Daniel, Head of the Research Unit “Type 1 Diabetes Immunology” 🎙️What was your career booster? 🗨️“Not doing it alone - a supportive network of colleagues, mentors, friends, and family, as well as taking turns not only in private, but also professionally and collaboratively. While there has certainly been an element of chance, seeking and then also daring to seize opportunities has been invaluable.” - Prof. Julia Schnabel, Director of the Institute of Machine Learning in Biomedical Imaging @helmholtz_en @ja_schnabel @EleZeggini @METorresPadilla #WomenInSTEM #GenderEquality #InspiringWomen #WomenInspiringWomen #CelebrateWomen

Inspiring Careers – Insights on Female Leadership🚀 Am 11. März bringt #HelmholtzMunich inspirierende Frauen in Führungspositionen aus Wissenschaft und Wirtschaft zusammen. Sie teilen ihre persönlichen Karrierewege, entscheidende Meilensteine und die Herausforderungen, die sie auf ihrem Weg an die Spitze gemeistert haben. 💡 Welche Erkenntnisse können wir aus ihren Erfahrungen gewinnen? Welchen Rat würden sie ihrem jüngeren Ich geben? Nimm an einer offenen Diskussion teil, vernetze dich mit Gleichgesinnten und gewinne neue Perspektiven für deinen eigenen Karriereweg. 👉Mehr Informationen und Link zur Voranmeldung: t1p.de/j21rr ✨Mehr über unsere aktuelle #WomenAtHelmholtzMunich-Kampagne: t1p.de/92d5l @MatthiasTschop @IBM @ETH_en #FrauenInFührung #InspiringCareers #Karriere #ScienceNeedsHer #WomenInScience #WomenImLead #SalonLuitpold

Opening of the "STEM Passion" Exhibition at #HelmholtzMunich 👏 👉 t1p.de/n47a5 To mark the International Day of Women and Girls in Science, the "STEM Passion" exhibition was officially opened at the Helmholtz Pioneer Campus. 🌟 This inspiring multimedia project celebrates the achievements of outstanding female scientists and highlights the #diversityof their roles in #research. 🌟With this initiative, Helmholtz Munich reinforces its commitment to visibility and equal opportunities for #WomenInScience. 📅 The exhibition is open to visitors until March 13, and marks the start of an awareness month, leading up to International Women’s Day on March 8. Helmholtz Munich shines a spotlight on the brilliance of female leaders in research, because #ScienceNeedsHer. 👉 Discover more about #WomenInScience at HelmholtzMunich: t1p.de/mddsr @helmholtz_en @ElisabettaCitt1 @CaglianoClaudia @Traidl_Hoffmann @ja_schnabel @zeynepakata @susedi2009 @EleZeggini @DeshwalSoni @PioneerCampus #STEMPassion #Inclusion #GenderEquality #Leadership #InspiringCareers #WomenInSTEM #WomenEmpowerment #GenderEquality #WomenInLeadership

Today, our HRD hosted a thrilling 3-Minute Thesis Competition, where PhD students made their research accessible also to non-scientists - in just 3 minutes! We're so proud of all participants! 🎉 🏆 Huge congrats to the two winners Bhargavi Karna & Sandra Dirschl! #3MT

A JOURNEY INSPIRED BY WOMEN IN SCIENCE 📢 Join the exhibition at #HelmholtzMunich! Exhibition Opening & Networking Event: 📅February 11, 2025 ⏰ 3:00 - 8:00 PM 📍Helmholtz Munich, HPC-Building 👉 Register here: t1p.de/3yj3p 👉Discover more: t1p.de/dc497 Women Driving Scientific Progress 💡 This exhibition spotlights remarkable female scientists, their diverse careers, and their contributions to society. It showcases mathematics, computer science, natural sciences, and engineering through the eyes of exceptional female scientists and highlights passion, scientific excellence, and diversity in #STEM. 👉 Meet four leading scientists at the opening and get inspired how they are driving #health solutions by their work in #epidemiology, #neuroscience, #StemCellResearch, #diabetes, and #genetics. Features scientists at Helmholtz Munich are: 🌟 Prof. Annette Peters, studying air pollution’s impact on cardiovascular health. 🌟 Prof. Magdalena Götz, researching brain development and neurogenesis. 🌟 Prof. Carolin Daniel, investigating immune mechanisms in Type 1 diabetes. 🌟 Dr. @skimhellmuth, exploring genetic influences on immune responses. @PassionStem @CaglianoClaudia @LMU_Muenchen @EPI_Helmholtz @PioneerCampus @helmholtz_de @GulcinAbbaszade #WomenInSTEM #STEMPassion #GenderEquality #ScientificExcellence #DiversityInScience #HaunerChildrensHospital #nextgenerationeu

The #immunesystem of #children reacts differently to #cancer than that of adults. Researchers led by @BrodinPetter and colleagues at 🇸🇪 @karolinskainst and 🇸🇪 @KarolinskaUnsju gained new insights which could lead to new tailored treatments. dlvr.it/THbycL

Sana Biotechnology's first-in-human study of hypoimmune-engineered deceased donor islets shows insulin production & immune evasion without immunosuppression #Diabetes #T1D #CellTherapy ir.sana.com/news-releases/ne…

Online now: T-Switch: A specificity-based engineering platform for developing safe and effective T cell therapeutics dlvr.it/TGYwfX

Very excited about the first preprint from our lab @TU_Muenchen! This is a fun gene & cell therapy collaboration led by @SchmidtsAndrea's Lab. We use generative #AI to design new #CARTcell therapies. Check out Andrea's thread & thanks to the whole team! biorxiv.org/content/10.1101/…

T cells that have not undergone MHC selection can bind soluble antigens, such as proteins or peptides, without the need for MHC presentation. 😱😱sciencedirect.com/science/ar…

To make our fantastic CITE-seq data set of postnatal thymocytes accessible to the community, we have launched a shiny web app for interactive exploration. Go check it out! ccgg.ugent.be/shiny/htsa_thy… Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/col…

🚨Greetings from the HRD Retreat in Kufstein!🌍✨ Doctoral researchers from @helmholtz_diabc discuss #diabetes—from molecular insights to clinical translation. Keynote speach by @_DiegoBalboa_, plus career talks by Larissa Langfeld & Robert Fichter!💡 🔗helmholtzresearchschool-diab…

⭐️NEW PAPER OUT in @Nature⭐️ 🫀What is the relationship between the immune responses in the heart, blood, and tumor in patients with inflammation in the heart resulting from cancer immunotherapy (irMyocarditis)? This 🧵 breaks down the key findings 1/n nature.com/articles/s41586-0…

Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss go.nature.com/4eJizC8

New @Nature A mechanism for why durable weight loss is so difficult: epigenetic memory of fat cells nature.com/articles/s41586-0… @vonMeyenn @laurahinte