Case Western Reserve researchers aim to advance precision molecular imaging for cancer diagnosis and treatment | CWRU Newsroom | Case Western Reserve University case.edu/news/case-western-r…

Welcome to read the #Published paper #Pharmaceuticals Saccharomyces boulardii CNCM I-745 Supernatant Improves Markers of Gut Barrier Function and Inflammatory Response in Small Intestinal Organoids by Filipe Rosa et al. Enjoy reading: mdpi.com/1424-8247/18/8/1167

Really excited to have our story on a CYP17A1-independent androgen biosynthesis pathway out today! We think this could be a reason for why androgens are left with abiraterone tx in prostate cancer. @dsui_miami_uro @SylvesterCancer @PCFnews @ASCO @AACR rdcu.be/eS7kU

Tonight, Case Comprehensive Cancer Center Director Dr. Gary Schwartz was officially named the inaugural Peter and Laurie Weinberger Professor in Cancer Research. A well-deserved honor for a leader in the fight against cancer!

Fighting Cancer on All Fronts. Gary Schwartz leads a top cancer center, but still sees patients and meets regularly with community members as he pursues a clear vision: 'Everybody should have access to the latest advances in cancer medicine.' Read more: case.edu/think/spring2025/fi…

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📢#Specialissue: Advances in #Prostate #Cancer #Therapeutics ⏰Deadline: 30 October 2025 🎓Guest Editors: Dr. David Danielpour 📖Find out more at mdpi.com/journal/pharmaceuti… @MDPIBiologySubj

cGAMP production by cancer cells promotes anti-tumor immunity. A new study highlights the good and bad of cGAMP in the TME, with significant implications for clinical use of STING agonists. cell.com/cell-reports/fullte…

#WeekendRead! #NotOnlyInterferons! @nanyanlab &co show @MolecularCell that other than inducing pathogenic IFNs in lysosomal storage disorders, STING function as a proton channel to activate TFEB & induce lysosomal repair cell.com/molecular-cell/full…

This is very encouraging. I would like to know its applicability to other cancers.

Now online! Engineering sonogenetic EchoBack-CAR T cells dlvr.it/TJzNbl

Linoleic acid is the most abundant polyunsaturated fatty acid in the Western-style diet and has been implicated in promoting inflammation and cancer. In Science, researchers report a mechanism by which linoleic acid can activate the mTORC1 protein kinase, which coordinates growth and nutrient signals. Learn more: scim.ag/4bxxLSN #SciencePerspective

β-hydroxybutyrate facilitates mitochondrial-derived vesicle biogenesis and improves mitochondrial functions dlvr.it/TJzBmx

Happy International Women’s Day! We’re celebrating women who have changed the world. Here are all of the amazing women who have received the #NobelPrize and their remarkable achievements at the time of the award. Tell us about the women who inspire you the most - and why #InternationalWomensDay

No one better than @DrKarenKnudsen! Inspiring leadership focused on patients.

Congratulations to the Master of Science in Anesthesia Class of 2026 Austin and Houston cohorts for receiving their White Coats, a tradition that marks their official entry into the medical profession!

Excited to serve as Guest Editor for Pharmaceuticals’ new Special Issue: Advances in Prostate Cancer Therapeutics! We welcome research on novel treatments, resistance mechanisms, biomarkers, & personalized medicine. Submit by Oct 30, 2025! mdpi.com/journal/pharmaceuti… #ProstateCancer

Published in @ImmunityCP, @PeterFecci lab (@Dukeneurosurg), Jan 2025. Tumor-associated macrophages (TAMs), not tumor cells, are primary mediators of progression from progenitor-exhausted to terminally-exhausted T cell state in GBM. TAM-T cell interaction are typically prolonged and weak—promoting progression of T cell exhaustion; in contrast to the robust TCR stimulation in DC-T cell interaction that support the expansion of progenitor exhausted T cells. Progenitor-exhausted to terminally-exhausted T cells ratio (PETER) was directly correlated to response to immunotherapy. Accordingly, depleting TAMs through the CSF1R and CCL2 pathway increased PETER and enhanced response to immune checkpoint blockade. These findings underscore the potential of targeting TAMs to improve immunotherapy.

The CDC is launching a new study to relitigate the debunked vaccines & autism link, going against decades of research findings of no link. This move, backed by RFK Jr. & the Trump admin, comes amid a growing measles outbreak in Texas. nytimes.com/2025/03/07/healt…