Emerita Professor of clinical genetics , U of Manchester and MFT - long time Mancunian and NHS supporter. Always European. Enjoys travel and being a grandma!

Joined July 2017
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Only For Top iQ level What's the next number?
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CONGRATULATIONS @OfficialUoM on winning University Challenge. Fantastic effort by this young team! @BBC
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Waiting for it with bated breath!!
5th in this wonderful Oxford set series arrives on March 12th. Have preordered and can’t wait. Catch up with the previous 4 if you can!
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Handsome brute! Long live Larry!
Wish I could remember where I'd left that folder...
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Amazing life story.
When a professor - a man, of course - defended regulated prostitution as necessary for men's health, Woman of the Day Aletta Jacobs swiftly retorted, “If that is really your opinion, you are morally obliged to make your daughters available for this purpose.” Who knew that we would still be having this argument in 2026? Certainly not Aletta, born OTD in 1854 in The Netherlands, the first woman officially to attend a Dutch university and the first woman in her country to receive a doctorate in medicine. She was born into a liberal Jewish family and wanted to become a doctor, like her father, but women were denied secondary education in many areas, and entirely excluded from universities. After primary school, she rejected the limited "finishing school" option for girls - it was “idiotic”, she said - and she had to lobby the authorities persistently just to become one of the first Dutch women to attend high school. Persistent lobbying became the underlying theme of her life. None of the opportunities so readily available to men ever opened to Aletta unless she fought for them. She even had to petition the Dutch Prime Minister directly to be admitted to the University of Goningen in 1871 for provisional admission for one year, and thereafter to allow her to sit exams and graduate. In 1878, she earned her medical degree, and the following year, her doctorate, the first woman in the Netherlands to do so. Aletta spent some time observing women doctors in London and met Dr Elizabeth Garrett Anderson, the first female doctor in England, and her sister, Millicent Garrett Fawcett. They shared similar views on women’s suffrage and the education of women. Fully-qualified Dr Jacobs could not treat male patients - it was improper, indecent or unchaste for a woman to be in close proximity to male patients - and when she tried to take part in hospital clinical rounds, they would often refuse treatment or examination if she was present. At this point, I would have expected NHS Fife’s collective head to be exploding, but then I remembered. They too are only concerned about the comfort and feelings of men. Inevitably, Aletta established a practice in Amsterdam providing free care to poor women and children, and came up against a host of social problems that affected them most: widespread poverty, unhealthy working conditions such as long shifts without breaks for shop girls, repeated pregnancies harming the health of women, high infant mortality, sexually transmitted diseases among patients and especially among prostituted women. "During this time I saw with my own eyes the catastrophic results that frequent pregnancies can have for a woman." In 1882, she opened the world’s first birth control clinic and introduced the pessary (diaphragm) to the condemnation of her male medical colleagues, religious leaders, and others who called it disgusting and immoral because they thought it would lead to rampant adultery and invite divine punishment. "If contraceptives were available – could a childless world be the result? Would they promote adultery?…I found comfort only by realising that a baby is most women’s greatest wish, which they would give up only for very serious reasons." By 1883, Aletta was actively challenging the denial of the vote to women. She tried to register to vote. After all, existing electoral law did not explicitly exclude women: it granted voting rights to "citizens" who paid a certain amount of taxes, and she was an independent, taxpaying woman who ticked all the boxes. After a bit of head-scratching, the mayor and city council of Amsterdam admitted that even though, strictly speaking, the law didn’t actually *exclude* women, mumble mumble, something something…she should ask the Amsterdam District Court. The District Court decreed that she was not a citizen, even though she met the criteria, so she appealed to the Supreme Court. Shades of Canada’s Famous Five “persons” case here. Of course you are not a citizen, said the Supreme Court, and anyway, taxes for married women are paid by their husbands, blithely overlooking the fact that Aletta was a single woman. The government obligingly amended the constitution in 1887 to explicitly limit voting rights to "male" citizens, thus closing the loophole. Aletta responded by starting her lifelong campaign for women's suffrage, heading the Dutch Association for Women's Suffrage from 1894, and co-founding the International Woman Suffrage Alliance. She had ties with the USA’s Carrie Chapman Catt and devoted herself to women’s rights and pacifism on a full-time basis from her retirement from practice in 1903 until her death in 1929. Dutch women were granted the vote in 1919. "I feel happy that I have seen the three great objects of my life come to fulfillment during my life…They were: the opening for women of all opportunities to study and to bring it into practice; to make Motherhood a question of desire, no more a duty; and the political equality for women." "Fighting for what is right makes life worth living."
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Dian Donnai retweeted
Links to @Unique_charity single gene disorder guides are now displayed in DECIPHER on gene pages, therapies tabs and patient records #inclusion #informationforeveryone
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His cousins on the beach November 25
Marine iguanas are the only lizard species in the world that live and forage in the ocean, and they are found exclusively in the Galápagos Islands 📹kenzokiren
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Dian Donnai retweeted
"Media coverage and PATHFINDER2: hype, simplification, and free advertising". Our commentary new GRAIL Galleri study just published in: @TheLancetOncol thelancet.com/journals/lanon… From @mgtmccartney, @SullivanProf, @paulpharoah, @HoulstonLab_ICR, @AggarwalOnc (1/2)

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Dian Donnai retweeted
Just what we need! DNA methylation tests, iv vitamins, longevity clinic and wearables at a private club! I'd pay money not to be a member PS there is quite good evidence around diet/alcohol/health and you don't need any of this stuff to benefit from it thetimes.com/life-style/heal…
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27 Nov 2025
RT @LucyMPowell: Here's why I'm backing the budget:
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4 Nov 2025
18?
How many birds are there?
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3 Nov 2025
Outstanding Goldsworthy exhibition in Edinburgh
Loved this ,a timely reminder there is often beauty in the most unlikely of places. Happy Monday 😊
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23 Oct 2025
Adelphi Genetics Forum annual@conference
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23 Oct 2025
2025 Adelphi Forum Conference at Royal Society. Diane Paul from Harvard giving a historical perspective on the realities of newborn Screening
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Dian Donnai retweeted
A wonderful year of great work.
Discover our key achievements 2024/25, including 👇 👥 Collaborative working 🤝 Equality, Diversity and Inclusion 💬 Patient and Public Involvement and Engagement 🎓 Academic career development 🥼 Working with industry 🔍 Impact case studies Read here 👇 manchesterbrc.nihr.ac.uk/new…
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Dian Donnai retweeted
When I first heard about Lucy Letby's case, I had no reason to doubt the allegations against her. I began following the case because, as a neonatologist with a further interest in risk management and patient safety, I felt I needed to understand how it could possibly happen that someone could murder or attempt to murder any babies on my unit without anyone seemingly noticing or doing anything about it. I worried - could this have happened to me and my colleagues? And I hoped if it had, we would have noticed and acted on it properly much sooner. As I followed the case via the media, I became increasingly confused by the medical evidence being presented. At first, I assumed the journalists simply didn’t understand the expert testimony and were not reporting correctly - surely no one could genuinely believe claims as medically absurd as babies being murdered by injecting air into a nasogastric (NG) tube? I had this conversation with many colleagues - Neonatal consultants, doctors in training and neonatal nurses. We were all really shocked by what was being reported. But I decided to wait until after the trial concluded before forming any real opinion as it was only then that enough information would become available that would make it clear as to what was actually said. After the convictions, like many of my colleagues, I sat down to watch the interview with aspiring TV star doctor Ravi Jayaram. My jaw dropped as I heard his appallingly misleading statements about extubation made on national television. I have still kept the messages I exchanged with Neonatal colleagues that evening. All of us who watched were saying - surely he didn't just say that the only possibility for a 25 weeker to have extubated was for it to have been done deliberately? I cannot even begin to explain how absolutely ridiculous that statement is. The sensational manner in which it was also delivered immediately made me ask myself - did I make a cognitive error in assuming no actual real doctors could have said the medical nonsense reported by the journalists? Is it possible that the experts and medical witness doctors involved really have said things that were so ridiculous in court and got the judge and jury to believe this nonsense? I then started looking through the information publicly available post-trial and I discovered that yes, this kind of flawed medical reasoning had indeed been accepted as fact. I was really shocked and decided to speak up, which I did as soon as the media gag was lifted. Thank you to Felicity Lawrence @guardiannews for making me feel safe to speak up. At the stage when I first spoke up, I still didn’t know whether Lucy Letby was innocent. What I did know, however, was that the medical basis of her conviction was deeply flawed. I also knew - but this is due to my law degree rather than me being a Neonatologist - that there were multiple legal reasons for why this conviction was unsafe as well. However, I wasn't as interested in this as I wouldn't want for someone's sentence to be quashed on legal grounds if they were genuinely guilty. It remained possible, as far as I could see, that Letby had harmed the babies. What was certain, however, was that if she did, she certainly didn't do it in the way that was claimed. However, it stands to reason that a serial killer could more easily operate in a unit where substandard care was the norm - when overall competence is low, people are far less likely to recognise when something is seriously wrong - something I know very well from personal experience of being a clinician dealing with risk, and having worked for the CQC and the Ockenden inquiry. After some time, I was instructed as an expert in the case. I took some annual leave and temporarily left the Ockenden review so I could give myself some time to properly look through everything. I then discovered many incidents of significantly substandard care with subsequent lack of insight by the clinicians involved and an almost complete absence of meaningful learning from mistakes. Unfortunately - neither of these are uncommon events in maternity and neonatal care these days. And neither is scapegoating someone. However - what was truly stunning in this case, and was definitely new to me at that point in time, was scapegoating via the criminally convicted serial killer route (usually people are just bullied out via employment tribunals, GMC/NMC and occasionally via the criminal courts for Gross Negligence Manslaughter route). For one year now, I have lived with the knowledge that a committed hard working competent nurse is in prison for crimes that never happened, whilst the doctors responsible for very poor care remain celebrated as “heroes” and continue practising without consequences. And the medical experts also continue to practise with no consequences. Putting this out here for the record. Not much else I can do. Thank you so much to @drphilhammond for continuing to expose this disgraceful MoJ. @drphilhammond @legalmarkmc @DavidDavisMP @DavidRoseUK @PeterElston1 @Michelehal7344 @reasonoverfear @DOckendenLtd @wesstreeting @PrivateEyeNews @Jeremy_Hunt @MartynPitman @Voice4theDead
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Dian Donnai retweeted
Let's get this post past the 100K mark.
Let this sink in…
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24 Aug 2025
Parsonage Gardens in Didsbury never disappoints @Parsonagetrust
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