Aging is arguably the root cause of most major diseases (loss of function in our cells). Four years ago, we made a bet that aging was treatable, and NewLimit was born. NewLimit now has a prototype drug that reverses the age of some human cells (restores function they had when they were younger), and a clinical trial scheduled for next year (with more drug candidates in the pipeline). Grateful to Founders Fund, Thrive, Greenoaks, and the rest of the investors for this latest round. @jacobkimmel and the team are just getting started.

Introducing model routing to Factory. Factory Router picks the right model for every task, automatically. Maintain frontier performance while cutting costs by 25%.

Claude Code creator: "Now I don’t prompt Claude anymore - I have loops that are running. My job is to write loops." In this 30-min speech, Boris revealed his actual Claude setup for daily coding. Claude Code loops dynamic workflow Worth more than a $500 vibe-coding course

BREAKING: President Trump orders ALL Federal agencies in the US Government to immediately stop using Anthropic's technology.

Figma CEO Dylan Field just identified the only competitive advantage that AI cannot commoditize. It isn’t your technical skill. It isn’t your speed. It isn’t your tools. Field: “If an agent can do it for you, an agent can do it for someone else.” That’s the fatal flaw in the entire AI productivity argument nobody wants to say out loud. When execution becomes free, execution becomes worthless. The moment anyone can build anything by typing a prompt, the output stops being the differentiator. What remains is taste. The one thing the agent cannot generate for you. Field: “What is different about your setup than others?” If you are typing generic prompts and accepting the first output the agent hands you, you aren’t building a product. You are retrieving a commodity. The same commodity available to every competitor on earth. Field: “You at least have to have something different there in order to not think that you’re just gonna get the same out.” But taste alone isn’t enough. The other half is exploration. Field: “The more you can sample the possibility space, it gives you something to react to.” The blank page is gone. The new constraint isn’t creation. It’s selection. The agent generates hundreds of possibilities in seconds. Your job is to go wide enough to find the best one hiding inside all of them. And then be honest enough with yourself to know when none of them are good enough. Field: “If you find areas where you’re going, ‘Hey, I don’t feel like I am liking this enough,’ then you got to keep pushing.” The creators who win this era won’t be the fastest builders. They’ll be the harshest critics. The ones who can generate the widest possibility space and identify the single best solution inside it. The ones whose taste is specific enough, developed enough, and honest enough to reject everything the agent produces until it produces something worth keeping. The AI can build anything you can describe. It cannot want anything. It cannot feel when something is wrong. It cannot tell the difference between good and extraordinary. That gap is the only moat left.

🚨Chinese AI labs just dropped 3 frontier open-source models ~3-20x cheaper than the US in the last week I made this benchmark price cheatsheet with everything you need to know. Minimax M2.5: Ultracheap, great for coding Kimi K2.5: all-rounder, best for OpenClaw Zhipu GLM-5: Premium all-rounder