Doloff Lab: Immunoengineering & Regen Med @TTECJHU | Ugrad @Penn @PennBioeng | PhD @BU_Tweets | Postdoc @MIT | Assoc. Prof. @JohnsHopkins @JHUBME DEI FLI YNWA!
Joined October 2018
- Tweets 4,139
- Following 1,257
- Followers 2,141
- Likes 12,573
360 Photos and videos
Joshua C. Doloff retweeted
Jun 12
New research by #HopkinsBME engineer @JustusKebschull reveals the brain contains 28 distinct types of dopamine neurons—far more than scientists previously thought. 🧠✨
Read more 👉 bme.jhu.edu/news-events/news…
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Joshua C. Doloff retweeted
A new #review from the lab of Dr. Joshua Doloff (@DoloffLab) at @JHUBME highlights how canonically non-immune cells interact with #biomaterials to shape immune responses, and argues for their greater integration into biomaterials research.
Read the @CellBiomat review: bit.ly/3SrUIRG
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Joshua C. Doloff retweeted
I've been to 100s of scientific conferences. I've never seen a technical talk get cheers, much less a standing ovation, but this result on pancreatic cancer really deserves it
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
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May 29
New commentary Immune-competent new approach methodologies for a hybrid future (w/ animal models) just out @NatImmunol! Congrats to co-1st authors @VanceSoares & @victorquiroz68! And co-corresponding authors @MTrapecar & @deokkim1!
nature.com/articles/s41590-0…
@JHUBME @TTECJHU
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Joshua C. Doloff retweeted
May 28
12 #HopkinsBME undergrads have been selected for two of the university’s top summer research fellowships. From PURA projects on pain, imaging, & AI to BDP research in epigenetics & chromatin biology, they’ll spend the summer advancing medical innovation.
bme.jhu.edu/news-events/news…
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May 25
New OpenAccess @CellBiomat review “Immune roles of canonically non-immune cells in biomaterial response” from our teams!
sciencedirect.com/science/ar…
@JHUBME @TTECJHU @JohnsHopkins @HopkinsEngineer @HopkinsMedicine
P.S. - Hope everyone has a safe and meaningful Memorial Day.
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May 25
Evidence of these immune-related functions of canonically non-immune cells appears in the biomaterials literature, most frequently in the contexts of fibrosis, cancer, tolerance, and tissue regeneration.
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May 25
However, these findings are often treated as secondary rather than explored in depth. As a result, this emerging area represents a substantial opportunity for both mechanistic discovery and therapeutic innovation.
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Joshua C. Doloff retweeted
May 22
Celebrating the @JohnsHopkins BME PhD graduates with a few behind-the-scenes moments from the ceremony! 🎓✨ Congratulations to all of the graduates on this incredible achievement!
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May 21
Congrats to our 2nd and 3rd @DoloffLab @JHUBME PhDs Jessica Stelzel and @stuart_bauer!
Keeping the bobblehead tradition (1 for mentee & 1 for mentor) alive that my lab started for my birthday, w/later post-it-folded face mask addition during covid!
@HopkinsMedicine @TTECJHU
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Joshua C. Doloff retweeted
May 17
The heart’s constant beating may actively suppress tumor growth in cardiac tissues, a new Science study reports. This is because cellular pathways in these tissues alter gene regulation in cancer cells to keep them from proliferating.
The findings shed light on the role of mechanical forces in protecting the heart from cancer and may pave the way to new cancer therapies based on mechanical stimulation.
Learn more: scim.ag/4cWFImV
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Joshua C. Doloff retweeted
May 18
Very interesting and important work from Bahareh Ajami’s lab 🤩|| Spatial proteomic analysis in human Alzheimer’s disease brains enables identification of microenvironment-dependent microglial cell states | Nature Neuroscience nature.com/articles/s41593-0…
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Joshua C. Doloff retweeted
May 14
Aged circulating cytotoxic T cells are drivers of age-related cognitive decline. Removal of aged T cells, or their secreted factor granzyme K, rescues cognition in mice @ImmunityCP @VilledaLab @UCSF
cell.com/immunity/fulltext/S…
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Joshua C. Doloff retweeted
Our latest paper is out @ScienceTM! Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts | Science Translational Medicine science.org/doi/10.1126/scit… #Immunotherapy #Fibrosis #Aging #Senescence #NKcell
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