Very happy to share that the Holly Lab will be opening at the Center for Molecular and Behavioral Neuroscience @Rutgers_Newark in Jan 2023! We’ll study the neural circuits driving decision making, and how these circuits and behaviors are changed by stress. Recruiting @ all levels
Attention neuro PhD-seekers: Many schools aren't recruiting, but our doors are still open. Our PhD program offers world-class labs and 5 years of guaranteed funding for *all* students. Meet our faculty and apply at cmbn.rutgers.edu. Apps due Dec 15. Also . . .
The Behavioral and Systems Neuroscience Area in Rutgers Psychology is now hiring a tenure track assistant professor. Rutgers has a great Neuroscience community and is a fantastic place to work!
Please share!
jobs.rutgers.edu/postings/23…
Are @SfNJournals JNeurosci Journal Club articles still a thing? My graduate student has sent multiple emails trying to reserve an article and no one has responded.
Be cautious when interpreting the results from reinforcer devaluation procedures
Insensitivity to reinforcer devaluation can arise even using only model-based planning and does not require or imply any habitual, model-free component
sciencedirect.com/science/ar…
Folks- I have a preprint update on our #dopamine quest:
"Cholinergic Interneurons Drive Motivation by Promoting Dopamine Release in the Nucleus Accumbens". I will try to summarize it here:
biorxiv.org/content/10.1101/… 1/9
Meet Dr. Angélica Torres-Berrìo @angelica_atb is a postdoctoral fellow at Mt. Sinai in @EricJNestler lab. Her work focuses on understanding how early life stress leads to enduring epigenetic changes in the brain’s reward system.
I don't tweet much (or ever), but this is really important to me! senior postdocs, Please apply to be a P-SPINE fellow (spinephilly.org) and come hang out with the Philadelphia neuroscience community in October. will be worth it!
It's that time! Time to announce the 2nd Philadelphia Symposium for Postdoctoral Initiatives in Neuroscience Excellence (SPINE)! This year, SPINE will take place IN PERSON at Penn on Friday, October 7th, 2022. Visit the website (spinephilly.org) for more info!
How regionally distinct are striatal dopamine signals? What type of events shape them? We just published a study in which we quantified dopamine release in response to appetitive and aversive stimuli in six principal striatal regions (1/5): pnas.org/doi/full/10.1073/pn…#Dopamine2022
I'm very excited to share this preprint by @neuronair: we show that hypothalamic neurons form an approximate line attractor whose ramping activity correlates with escalation of aggressive behavior in mice. 1/7
biorxiv.org/content/10.1101/…
Please RT: We are hiring! Seeking a postdoc. research scientist, or advanced technician for an externally funded project on multi-focal neural ⚡️stimulation ⚡️ and value-based decisions in nonhuman primates. Requirements: Must love the 🍾🍿🍾 of in-vivo neural activity...
Happy to see this paper out today. A great collaboration with colleagues in the UK. Cells that make dopamine and cells that make acetylcholine work together in a precise timing arrangement to identify the exact brain circuits to reinforce during learning.
nature.com/articles/s41467-0…
Sharing our last study from my postdoctoral work in PR (2016-18)! This also represents the last paper from #QuirkLab on the Island. Thx! Seguimos!
biologicalpsychiatryjournal.…
They’re also critically involved in learning, and locally gate striatal dopamine. Quite possibly the most interesting neurons in my extremely biased opinion.
An LTS neuron in the striatum. They’re NOS and SST , will express from the CaMKII promoter, and like to hug the edges of striosomes. There’s much more to say about these often neglected neurons but I will keep between myself and Cajal.
So excited to share our new paper on insula! We found a pathway from the anterior insular cortex to brainstem nucleus tractus solitarii that controls motivational vigor and dopamine release in a learning- and need-dependent manner. Please check it out:
authors.elsevier.com/a/1eDNs…
Excited for my first in person #ACNP2021 - I’m a senior postdoc studying how corticostriatal circuits drive decision making, and how these circuits and behaviors are changed by stress history. I’m also on the job market!
ACNP/NPP gift card giveaway swag will be back this year! If you're an early career investigator attending #ACNP2021 - QT to introduce yourself and your research, tag in @npp_journal and @ACNPorg and we'll include you in a drawing for a gift card on Sunday evening.
food and social rewards are just as interesting as drug rewards. 😊🍭
let’s talk reward, NAc, and sex differences! come chat w/me Tuesday 5:30-7:30, poster no. T108 !
Here's a new dopamine idea we have been cooking for a while now. I think it's palatable now: Striatal dopamine pulses follow a temporal discounting spectrum. I will try to explain a few chirps, but to get the full story read our preprint. 1/n
biorxiv.org/content/10.1101/…
Delighted to share that my most important PD paper was published in @npp_journal ! 🎉✨
If you only read only one of my papers, please make it this one! Limited bedding compromises VTA DA function in mom (short-term) AND adult female offspring (long-term)
nature.com/articles/s41386-0…