@EnginLaboratory profile picture
Feyza Engin @EnginLaboratory
Joined December 2017
  • Tweets 680
  • Following 182
  • Followers 1,802
38 Photos and videos
Feyza Engin retweeted
TV100
@tv100
May 28
🐬İstanbul'un turkuaza bürünen sularında dolaşan yunus balıkları görüldü.
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The turquoise waters of Istanbul 😍
Hava Forum
@HavaForum
May 28
İstanbul'da turkuaz denizde yunuslar "günaydın" şovu yaptı.
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Feyza Engin retweeted
Hotamışlıgil Lab@gshlab
Apr 28
We are extremely proud and thrilled to announce our very own Dr. Hotamışlıgil @ghotamis has been elected to the National Academy of Sciences!! Congratulations on this outstanding achievement and recognition 👏👏👏😊nasonline.org/news/2026-nas-…

National Academy of Sciences Elects Members and International Members - NAS

WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 25 international members in recognition of their distinguished and continuing achievements in original...

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I am so proud of my mentor Gokhan Hotamisligil for his election to the National Academy of Sciences! Such a well deserved recognition! 🧿 @ghotamis
National Academy of Sciences@theNASciences
Apr 28
We are thrilled to announce the election of 120 members and 25 international members to the National Academy of Sciences in recognition of their distinguished and continued achievements in original research. Congratulations to our new #NASmembers and welcome to the Academy! 🎊
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Here is the eprint of our recent review science.org/eprint/ZVKVHQ58B….

Beyond bystanders: How β cell stress shapes the autoimmune response in T1D

β cell stress not only drives loss of functional β cell mass but also may fuel autoimmunity in type 1 diabetes.

science.org
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Feyza Engin retweeted
Waggoner Lab@LabWaggoner
Mar 26
Review @ScienceTM @EnginLaboratory β cell stress not only drives loss of functional β cell mass but also may fuel autoimmunity in type 1 diabetes science.org/doi/10.1126/scit…
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I’m excited to share that our review article, co-authored with my colleague Dr. Decio Eizirik, is out today in Science Translational Medicine. science.org/doi/10.1126/scit…

Beyond bystanders: How β cell stress shapes the autoimmune response in T1D

β cell stress not only drives loss of functional β cell mass but also may fuel autoimmunity in type 1 diabetes.

science.org
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Feyza Engin retweeted
EuroFoot
@eurofootcom
5 Dec 2025
🇳🇬💥 Victor Osimhen (26) with a FANTASTIC winning goal for Galatasaray. It was in the 92nd minute too! 🔴🟡

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Our new paper is out now in Nature Communications! We uncovered the function of XBP1 in beta cells of a preclinical model of T1D and identified unique and shared gene regulatory networks driven by IRE1 and XBP1. nature.com/articles/s41467-0…

Defining the role of β-cell IRE1α/XBP1 pathway and its gene regulatory network components in...

Nature Communications - Modulating the unfolded protein response (UPR) can induce protective dedifferentiation of β-cells in non-obese diabetic mice. Here, the authors show that β-cell...

nature.com
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We extend our sincere gratitude to our outstanding collaborator, Sushmita Roy, her team, the reviewers, and the editor. Congratulations to all authors!
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Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy | Nature nature.com/articles/s41586-0…

Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy

Nature - Acetyl-coenzyme A functions as a non-canonical signal to trigger mitophagy, and the acetyl-coenzyme A–NLRX1 axis underlies the KRAS-inhibitor-induced mitophagy response and promotes...

nature.com
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Feyza Engin retweeted
UEFA Champions League
@ChampionsLeague
5 Nov 2025
Hat-trick ⚽️⚽️ ⚽️ Three POTM awards in a row 🏆🏆🏆 Victor Osimhen 👏👏👏 #UCL
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Feyza Engin retweeted
UEFA Champions League
@ChampionsLeague
30 Sep 2025
Galatasaray beat the English champions. #UCL
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Feyza Engin retweeted
Guy Rutter1@guy_rutter
30 Aug 2025
Our new report with #YaChiHuang ⁦#MarjanRupnik using high-speed imaging in pancreatic slices. Pancreatic α-cells are functionally heterogeneous and sex-dependently regulated by neighboring endocrine cells | bioRxiv biorxiv.org/content/10.1101/…

Pancreatic α-cells are functionally heterogeneous and sex-dependently regulated by neighboring...

Glucose and paracrine regulation on α-cells, particularly with respect to sex differences, remains unclear. Hence, we imaged islets of GluCre:GCaMP6ffl/fl mice in pancreatic slices, additionally...

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We are hiring! I am recruiting a postdoctoral fellow to join us studying cell stress responses and organelle communication in pancreatic beta cells. Cell and molecular biology background is highly desired. Interested? please contact me at fengin@wisc.edu. hr.wisc.edu/postdoc-and-rese…

Postdoc, Postgrad, and Research Intern Vacancies

Browse Postoc and Research Intern vacancies at UW–Madison.

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Mitochondrial origins of the pressure to sleep | Nature nature.com/articles/s41586-0…

Mitochondrial origins of the pressure to sleep

Nature - Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.

nature.com
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Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication: Cell Metabolism cell.com/cell-metabolism/ful…

Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication

Tong et al. utilize advanced imaging approaches to reveal that beta cells located next to alpha cells are specially adapted as glucagon sensors by virtue of their high expression levels of GLP1R....

cell.com
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ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox | Science science.org/doi/10.1126/scie…

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox

Maintenance of mitochondrial redox homeostasis is of fundamental importance to cellular health. Mitochondria harbor a host of intrinsic antioxidant defenses, but the contribution of extrinsic,...

science.org
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Feyza Engin retweeted
Vamsi Mootha@VamsiMootha
10 Jul 2025
Wow, fatty acid oxidation in neurons! Time to update the textbooks?!
Nature Portfolio
@NaturePortfolio
10 Jul 2025
A study in @NatMetabolism shows that under glucose-depleted conditions, neurons can use fatty acids as an alternative source of energy to support synaptic function. go.nature.com/46ArR2G
This is figure 1, which shows DDHD2 lipase localizes to synaptic terminals in the hippocampus.

ALT This is figure 1, which shows DDHD2 lipase localizes to synaptic terminals in the hippocampus.

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If this is strictly true then it will devastate discovery science in fields like endocrinology and metabolism where there are no meaningful substitutes for physiological studies in whole mammals that can genetically modified in a tissue specific and temporally controlled manner
Marcus Goncalves
@MarcusDGon
8 Jul 2025
NIH no longer award funding to new grant proposals solely relying on animal testing. drugdiscoverytrends.com/nih-…
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