Professor of Medicine-UCSD-Molecular cardiologist-Entrepreneur- Uncovering new therapeutic targets for genetic based cardiac diseases #ARVC Tweets are my own.
📣🎉 Exciting news! Our lab’s new paper in #CirculationHeartFailure reports a gene therapy for arrhythmogenic cardiomyopathy. Restoring connexin-43 improves electrical & mechanical coupling, rescues disease & extends survival across severe ACM genotypes.
ahajournals.org/doi/10.1161/…
I’m honored to keynote @UOHIResearch Research Day and share our bench-to-bedside work toward therapies for arrhythmogenic cardiomyopathy. #ARVC#HeartResearch 🧬🫀
Research Day is only a few days away!
We’re thrilled to welcome our keynote, Dr. Farah Sheikh, as she takes us from bench to bedside in developing therapies for genetic heart disease. 🥼🔬
Don’t miss it- you can watch online or in-person!
Register here:bit.ly/42MpJBJ
📢 New publication on AAVrh10-based plakophilin-2 gene therapy, showcasing exciting preclinical data supporting the recent encouraging LX2020 Phase 1/2 trial results in ARVC patients. Thanks to Sheikh lab team & LEXEO Therapeutics! #ARVC#GeneTherapy#PKP2nature.com/articles/s41536-0…
🤯 Unbelievable to see the exciting progress made in advancing therapies in genetic medicine for patients, including for patients with ARVC! Grateful to LEXEO and ARVC patients that have made this possible. #ARVC#PKP2
APS members: Voting on the proposed bylaws changes (governance modernization initiative) is now open: ow.ly/UQay50RIVHo. APS login required, deadline is 6/6.
Remembering the #BCVS23 Lunch with Legends, where early career scientists got to chat with impressive mentors, including AHA president @Joseph_C_Wu.
Join us in Chicago for #BCVS24 July 22-25 and make connections that could change the course of your career. @BCVSearlyCareer
Grateful for the spotlight, shedding light on my journey! It’s been a humbling experience, from research to real-world impact. Heartfelt thanks to mentors, partners & all past & present Sheikh team for their dedication to make a meaningful difference in the fight against #ARVC.
Don't forget, March 13th is the deadline for abstracts and award applications for #BCVS24, to be held in Chicago 22-25 July! This includes nominations for the BCVS Early Career Investigator Award. @ECI_ISHR@aha
🔬 Experiments detailed in this study by the @FarahSheikhLab suggest that AAV-PKP2 gene therapy holds promise for circumventing ARVC associated with PKP2 mutations, including splice site 📍 mutations.
@NatureComms | go.nature.com/41bmJgK
So 👇 happened in Times Square yesterday!! Moving from bench to bedside to Wallstreet 🤯! Grateful to LEXEO in moving cardiac (ARVC) ❤️ precision based gene therapies forward!! 💪🗽#ARVC#NASDAQ
Exciting times ahead for gene therapy programs, including ARVC, as LEXEO becomes one of the small number of companies that goes public!! #genetherapy#ARVC#NASDAQ 💪🎉🚀
@ajpheartcirc@APSCVSection We are soliciting nominations for the Fellow of the APS-CV section. Please send the nomination to the Chair of the CV section Fellowship Committee (lyin@neomed.edu) by February 15, 2024. The website link is (physiology.org/community/aps…).