Pre-seed VC. Investing with conviction in visionary, technical founders inventing the future. #ML #AI #Climate #techbio @DrewVolpe @MITMillieLiu @teddypowday

Joined September 2016
53 Photos and videos
First Star Ventures retweeted
Nicholas Arcolano, head of research at Jellyfish, told TechCrunch via email that expenditure on AI is exploding in large part due to agentic features, with per-developer consumption rising about 18.6x in nine months. All in all, these stats make the productivity case murkier than the spending suggests. “Whether extreme spend pays off comes down to the ultimate business value of shipped code (e.g. revenue), which most companies still can’t measure,” Arcolano said. According to Arcolano, the smart move is broad, moderate adoption. “The best ROI comes from moving the broad middle from low to moderate usage, not pushing heavy users higher,” he said. Learn more: techcrunch.com/2026/06/05/th…
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First Star Ventures retweeted
📈 Token consumption is on the rise...to no one's surprise. Jellyfish research recently published an AI Engineering Trends report showing just how drastic the jump has been year to date. In May, P90 is at 173M weekly tokens/user. How does your R&D org stack up? Dive into the data here: jellyfish.co/ai-engineering-… #AIEngineeringTrends
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First Star Ventures retweeted
🦓 Progress in the rare disease space is accelerating like never before! Catch the @iOrganBio team next week in Boston at the 2026 World Orphan Drug Congress as we connect with other innovators who are tackling some of the biggest challenges in medicine. COO @karol_jarzabek and BD Lead Lucas Abbott will be in Boston to share how iOB’s CellDiscovery™ Platform is enabling generation of personalized drug discovery models and powering n-of-one clinical trials for rare diseases, and the CellForge™ Platform is enabling scale-out and scale-up of precision cell manufacturing. Together with our partners, we’re helping to transform the approach to rare diseases, unlocking new approaches to personalized therapy development and bringing hope to patients and their loved ones with The Right Cells, Consistently, At Scale. 📝 Register for WODC 2026 at terrapinn.com/conference/wor… 🌐 Learn more about iOB’s technology at iorgan.bio/ ✉️ Explore partnering opportunities by emailing partnering@iorgan.bio #RareDisease #OrphanDrugs #WODC #PersonalizedMedicine #Nof1 @orphan_drugs @OrphanConf
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First Star Ventures retweeted
The idea of scaling autonomy is simple on paper: build more trucks to haul more freight. But the reality is being strategic about what an autonomous network looks like, and understanding that autonomy removes one of the biggest questions in network design: does the labor exist to make a location in my network make sense? That's what Brett Suma is here to answer. freightwaves.com/news/bot-au…
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First Star Ventures retweeted
It's finally here! ✨ The GLOW 2026 video series features Leading Voices at the Intersection of AI and Engineering from @LoadsmartUS, @Q2_Software, @incident_io, @googlecloud, @awscloud, @Avaya, @blitzyai, @OpenHandsDev, and more...and these under-20-minute episodes are now available for you to watch anytime, anywhere. Software was eating the world. Now AI is eating software. But you're not alone. Watch the first 4 episodes and learn how AI is changing how teams build, measure and deliver impact in modern engineering organizations: jellyfish.co/glow #GLOW26 #AIFirst #AIIsEatingSoftware
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Welcome Dr Pang!
iOrganBio is excited to share the addition of Zhiping Pang to our Scientific Advisory Board. As one of the world’s foremost experts in human neuron biology, synaptic function, and the molecular mechanisms underlying neuropsychiatric and metabolic disorders, Dr. Pang has co-authored over 140 publications in top journals. As @iOrganBio continues to build our technology platform, we’re grateful to have expertise and guidance from the world’s foremost scientists, engineers, and industry leaders. Together, we’re proud to be re-shaping how cell-based research and therapies are developed, expanding access to life changing therapeutics. 🚀 Welcome aboard Zhiping! 📰 Read the full press release at iorganbio.reportablenews.com… 🌐 Learn more about iOB’s technology at iorgan.bio #Neuroscience #Organoids #NAMs #DrugDiscovery #DrugDevelopment
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First Star Ventures retweeted
Excited to rep Boston and be one of the funds participating.
the team built a way for founders and investors to get intro'd at Tech Week! Use it May 26 (today) to Jun 7 to meet connect try it here: intro.tech-week.com how it works: - Founders sign up and say what they're building - VCs hit the same link for investor access, then browse and reach out directly why? tens of thousands of people come to Tech Week every year to build, launch, hire, etc. ~30% of Tech Week attendees are founders. Many are building the next big thing. But since Tech Week is decentralized, there's been no central place for founders and VCs to find each other. So we build this tool, which is only available for two weeks only during Boston NY Tech Week (from May 26-June 7) enjoy!
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First Star Ventures retweeted
Jellyfish SVP of Engineering Adam Ferrari reflects on findings from the 2026 State of Engineering Management report. In this short, he shares his reactions to AI costs and tool proliferation challenges. Watch the full video here: jellyfish.co/events-and-webi… And explore the report here: jellyfish.co/2026-state-of-e… #SEMR26 #StateOfEngineeringManagementReport #AICosts
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First Star Ventures retweeted
Long before modern medicine, people were deeply curious about what their body released. Western medicine made that taboo. That curiosity is worth reclaiming.
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First Star Ventures retweeted
Reminder, we're doing a fireside chat next week (Thu 5/28) in Cambridge with some awesome founders who are: - making human cells and tissue - monitoring gut health with smart toilet cameras - revolutionizing liquid biopsy Come hang out! (registration link next tweet)
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First Star Ventures retweeted
Today is World IBD Day, and my co-founder @JohnCapodilupo wrote something I hope you will read. There are two things you need to know about John: 1/ Before joining @ThroneScience , John was co-founder and CTO of @WHOOP , where he pioneered wearables and popularized metrics now used by millions, like HRV and sleep scores. 2/ Ten years ago, he was diagnosed with pancolitis, the most severe form of ulcerative colitis. I've said it a thousand times, and I'll say it a thousand times more: there is no one who more perfectly understands the value and importance of what we are building than John Capodilupo. Throne sits at the exact intersection of his personal and professional life. As you read John's blog, you will find he is a gifted and empathetic writer. He brings that same empathy to every decision he makes that shapes Throne. Throne is not a medical device and it's not a substitute for traditional care. But for the millions of people living with IBD, and the many more who simply want to understand their gut, we believe the toilet is the most underutilized data surface in the home. It's the adventure of a lifetime to build Throne with John. Read his piece here, and if you can, support the @CrohnsColitisFn today. thronescience.com/blog/world…
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Join us next Thursday, May 28th Heeding Nature's Call: Reading the Body with AI 👇
✍️ Design 🏗️ Build 💥 Test 💡 Learn These are the core engineering principles that guide the iterative design of everything spanning ballpoint pens to fighter jets. And now we can do the same for cells—completely automated—made possible by advanced robotics and AI. As part of Boston Tech Week, @iOrganBio Founder and CEO @DanielDelubac will be contributing to a panel discussing the intersection of deep tech and biomedical progress. Joining him for the Heeding Nature's Call: Reading the Body with AI are: @JohnCapodilupo of @ThroneScience and @WHOOP @LoyConor of @romixbio Moderated by @drewvolpe of @FirstStarVC, this fireside chat promises to be an engaging update on how deep tech is combining with biotechnology to transform human health. If you’re in Boston for @Techweek_ , you won’t want to miss it! 📝 Register for the event at partiful.com/e/MyfKGX0Dl8BiN… 🤖 Check out the full Boston Tech Week lineup at tech-week.com/ 🌐 Learn more about iOB at iorgan.bio/ #BOSTechWeek #AI #Biotech #Organoids #NAMs
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First Star Ventures retweeted
🌊 The next wave of AI transformation is here. Yet, most organizations still struggle to measure impact and prove ROI. Join Blitzy's CTO Sid Pardeshi and Jellyfish SVP of Engineering Adam Ferrari tomorrow as they break down what separates high-performing teams from the rest...and how your organization can learn from and apply those insights: jellyfish.co/events-and-webi…
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First Star Ventures retweeted
The AI-first era is here. Are you ready? Leading voices at the the intersection of AI and engineering featuring @Google Cloud DORA's Nathen Harvey, @blitzyai Nick DiFiore, @Avaya's Ruby Agarwal, @awscloud's Joe Cudby, @incident_io's Chris Evans, @OpenHandsDev's Robert Brennan, @LoadsmartUS Ron Ben Yosef, @Q2_Software's Jan Acosta, Jellyfish's @amlau, @augmentcode's Vinay Perneti, @flotracker's Vladislav Nedosekin, and many more are here to help. Start watching GLOW on June 2, 2026. #GLOW26 #AIEngineering
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First Star Ventures retweeted
as a peer to fervo, today feels like a good day to give them their flowers for their opening act. they started when nobody cared about geothermal or baseload power startups, trying to commercialize EGS; a technology with a 40 year graveyard of failures. anyone who does this for a living knows how brutal that path was. they had to survive so many firsts and so much painful company building. now for the second act: they're sitting on 2B in cash now. and unlike fusion or fission, that capital is going to turn into real MWh on the grid. no celebrating technical milestones that nobody understands, no "power is just a few years away" promises. no, those billions will generate new power. because at the end of the day, geothermal is just drilling, hot rocks, and thermal power plants. we know how to drill. we're getting better at finding the hot rocks. and we damn sure know how to build and operate the plants. it's a pretty cool moment. the future is bright.
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First Star Ventures retweeted
The 2026 State of Engineering Management Report finds that only 10% of teams report strong enablement and high adoption (of AI tools) across their organization. Head of AI & Research Nicholas Arcolano, PhD, and Engineering Manager Marilyn Cole react to this finding in this video. Explore the report for more insights here: jellyfish.co/2026-state-of-e… #SEMR26 #AICoding #AITransformation #StateOfEngineeringManagement
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First Star Ventures retweeted
Here's a look at the highlights from our humanless run from Houston to Dallas!
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First Star Ventures retweeted
HUGE thank you to Kurt Knutsson and Fox News for doing a deeper dig on our humanless run from Houston to Dallas. Kurt said it best in his article: next steps are repeatability and scale, and we are ready to tackle those head on! Read the full interview with Kurt and Bot Auto's CEO Xiaodi Hou here. foxnews.com/tech/humanless-b…
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