Joined June 2019
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46 Photos and videos
14 Jun 2023
Hey so this is pretty cool. Check out our lab's paper about Magnify, now on the cover of @NatureBiotech!
We also have a website, magnify.mcs.cmu.edu, where we have up to date protocols, FAQ, and contact info, where we've received lots of great feedback already!
14 Jun 2023
The June issue is live nature.com/nbt/volumes/41/is…
Our cover features an expansion microscopy technique developed by Klimas et al. that retains nucleic acids, proteins and lipids without the need for a separate anchoring step go.nature.com/3Iesy5L
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Brendan Gallagher retweeted
6 Jun 2023
Thrilled to celebrate the first PhD from our lab! His hard work, perseverance, and innovative research have set a high bar for future scholars. A journey of discovery begins with a single step, and his has taken a giant leap. Congrats, Dr. Gallagher @GallagherCMU ! 🎓🔬
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10 Apr 2023
📰 We wrote a News & Views article @NatureNano to discuss how researchers have combined Expansion Pathology & super-resolution radial fluctuations to achieve nanoscale resolution in pathology specimens using low-cost LED-based widefield microscopy. nature.com/articles/s41565-0…
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Brendan Gallagher retweeted
6 Apr 2023
Happy Graduate and Professional Student Appreciation Week! We appreciate all you do. MCS celebrated graduate students — including Berry Research Award winner Xuecong Fu and Young Teaching Award Samson Leung — with a luau-themed social.
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Brendan Gallagher retweeted
20 Mar 2023
Expanding Horizons – Expansion #microscopy strategy called #Magnify reveals nanoscopic subcellular structures. Video & research by Aleksandra Klimas & @GallagherCMU et al @huailang lab @CarnegieMellon in @NatureBiotech. More on bpod.mrc.ac.uk/archive/2023/… with @MRC_LMS & @esbriolat
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Brendan Gallagher retweeted
16 Mar 2023
A @SciReports paper presents a device called glowscope that can convert a smartphone or tablet into a fluorescence microscope for less than US $50. go.nature.com/3l35BJH
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Brendan Gallagher retweeted
14 Mar 2023
“Everything Everywhere All at Once.” More at 11.
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21 Feb 2023
Research Highlight by @rita_strack - A new twist on expansion microscopy called Magnify uses a mechanically sturdy gel to simultaneously anchor and expand diverse biological samples for super-resolution imaging.
nature.com/articles/s41592-0…
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Brendan Gallagher retweeted
26 Feb 2023
We are thrilled to share that our Magnify paper @NatureBiotech got a spotlight in @naturemethods, beautifully written by @rita_strack! This is a great honor and recognition of our work. We are grateful for her insights and support!
21 Feb 2023
Research Highlight by @rita_strack - A new twist on expansion microscopy called Magnify uses a mechanically sturdy gel to simultaneously anchor and expand diverse biological samples for super-resolution imaging.
nature.com/articles/s41592-0…
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Brendan Gallagher retweeted
23 Jan 2023
New Research Highlight! Yongxin Zhao et al developed an expansion microscopy technique that does not require a separate anchoring step, achieving a resolution comparable to super-resolution imaging techniques @huailang @CarnegieMellon @NatureBiotech
go.nature.com/3ZWahk8
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Brendan Gallagher retweeted
11 Jan 2023
Unprecedented views of the interior of cells and nanoscale structures are now possible thanks to innovations in expansion microscopy by @CmuScience's Yongxin (Leon) Zhao. The novel "Magnify" protocol uses a new hydrogel formula invented by Zhao's team. cmu.is/zhao-magnify
ALT Magnified cells.
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Brendan Gallagher retweeted
4 Jan 2023
New Nature paper provides evidence that science has become less innovative since the 1950s. The authors suggest reversing the trend by:
1. reading widely,
2. focusing less on quantity of papers, & more on research quality,
3. taking year-long sabbaticals.
nature.com/articles/s41586-0…
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Brendan Gallagher retweeted
3 Jan 2023
In general, we try to see more detail in biological samples by building better microscopes and playing with the physics of light.
Expansion microscopy comes at the problem from the other end by actually making the sample larger! New & improved approach published yesterday!
2 Jan 2023
Magnify is a universal molecular anchoring strategy for expansion microscopy go.nature.com/3Iesy5L
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Brendan Gallagher retweeted
2 Jan 2023
Our goal is to make Magnify as accessible as possible.
The paper is available to anyone. And we set up a website with protocols magnify.mcs.cmu.edu/
Also, plz contact my team for any technical questions or potential collaboration.
2 Jan 2023
Magnify is a universal molecular anchoring strategy for expansion microscopy go.nature.com/3Iesy5L
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2 Jan 2023
Magnify is a universal molecular anchoring strategy for expansion microscopy go.nature.com/3Iesy5L
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2 Jan 2023
A quick thread on what you (yes, you!) can accomplish with Magnify, our new ExM method out today in @NatureBiotech !
nature.com/articles/s41587-0…
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2 Jan 2023
Finally, when combined with SOFI, Magnify is able to achieve resolutions down to 15 nm, allowing us to see fine ultrastructure in human lung organoid cilia
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2 Jan 2023
Thank you again to all involved whose efforts made Magnify possible! On to the next 🙌
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Brendan Gallagher retweeted
2 Jan 2023
The press release: eurekalert.org/news-releases…
And our Magnify website is up! magnify.mcs.cmu.edu/news/
This is impossible without the heroic efforts of @OpticalComplex @GallagherCMU, the whole team and supports @CmuScience @CMU_Bio @NIH_CommonFund 🙏
2 Jan 2023
We kick start 2023 with Magnify @NatureBiotech, a facile Expansion Microscopy method that retains nucleic acids, proteins, and lipids! See nanoscopic details of cells and tissues with up to 15 nm resolution, even in clinical tissues and human organoids!🔬nature.com/articles/s41587-0…
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2 Jan 2023
Thank you again to all who made this paper possible! For any questions about the protocol or a good way to contact us, please visit the all new Magnify website!!
magnify.mcs.cmu.edu
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2 Jan 2023
We will be continuously updating this with new protocols, images, and publications, so be on the lookout for more exciting work to come!
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