Prof Michael Gantier's lab @Hudson_Research studies the immunology of nucleic acids (such as mRNA therapeutics)
Joined May 2021
- Tweets 89
- Following 131
- Followers 131
- Likes 314
1 Photos and videos
May 3
Ever wondered what happens to oligonucleotide therapeutics once they start to break down? In our new bioRxiv preprint, we provide a molecular dissection of how chemically modified 3‑base oligonucleotide fragments engage TLR7 and TLR8. Check it out! doi.org/10.64898/2026.04.29.…
28
Gantier Lab retweeted
Feb 27
Researchers led by Drs. Michael Gantier (@GantierLab), Toshiyuki Shimizu, and Ben Corry (@CorryLab) show that modified #RNA from our own cells naturally blocks TLR7 and TLR8, preventing harmful immune activation.
📖: go.nature.com/4azVWjp
🔊: bit.ly/40muGA2
1
5
219
Gantier Lab retweeted
Recognition of RNA fragments by TLR7 and TLR8 helps to initiate the innate immune response.
This work redefines TLR7 and TLR8 sensing by introducing 2′-OMe guanosine as a natural immune checkpoint for their activation. @NatImmunol
🔗 go.nature.com/4azVWjp
1
3
300
How does your immune system tell pathogenic RNA from your own, even though they’re made of the same stuff? Our latest paper with
@GantierLab
shows some self RNA act as an off switch preventing autoimmunity in the absence of pathogens. 🧬🔬⭐ nature.com/articles/s41590-0…
2
7
248
Feb 10
I am delighted to share our characterisation of natural antagonism of TLR7/8 in Nature Immunology. We propose a model where 2’O-Methyl RNA fragments keep TLR7/8 in check, preventing autoimmunity. > nature.com/articles/s41590-0…
1
12
28
2,073
Gantier Lab retweeted
IsomiR stoichiometry changes as disease biomarkers. dlvr.it/TLDYyK #MTNA
1
2
288
10 Jun 2025
Excited to share our latest work on how microRNA length variants can be leveraged as disease biomarkers. Congratulations to Alex McAllan for all her work on this!
cell.com/molecular-therapy-f…
2
2
178
15 Feb 2025
For all RNA scientists in the Melbourne area: Join us at the next RNA Victoria Minisymposium on 27th of March at the Hudson Institute of Medical Research - details about the speakers and free registration at rnavic.com/
1
1
246
27 Jun 2024
Please mark your calendars for the next RNAVIc symposium. It will be July 22nd at WEHI Davis Auditorium starting at 2pm. rnavic.com/
4
7
1,028
Gantier Lab retweeted
We are thrilled to announce the official launch of the #RNAte Platform at @Hudson_Research, delivering huge advances in the development of #mRNA-based therapies. 🥳💪🏽
Read more about this revolutionary platform: bit.ly/3SEEl23
@VicGovAu @VicGov_DJSIR
6
26
3,053
Gantier Lab retweeted
We recently welcomed Deputy Premier & Minister for Medical Research, The Hon @BenCarrollMP to Hudson Institute! 🙌
Minister Carroll went behind the scenes with some of our researchers, including our CEO & Director Prof Elizabeth Hartland, to learn more about our research.🔬
ALT Deputy Premier & Minister for Medical Research, The Hon Ben Carroll and Hudson Institute CEO & Director Professor Elizabeth Hartland
ALT Deputy Premier & Minister for Medical Research, The Hon Ben Carroll speaks with researchers at Hudson Institute
1
17
846
Gantier Lab retweeted
14 Dec 2023
Thrilled to be joining longtime friends and colleagues @CiiiD_Hudson including those I could find on twitter @ProfHartland @FerreroMicro @Tate_Lab @GantierLab @pjhpauljh @Forster_Lab @PhilBardin
5
1
40
1,819
Gantier Lab retweeted
22 Nov 2023
Exciting data to build our research program on thromboinflammation! So proud of this first research paper! Thanks to the many students and collaborators who contribute to this story! life-science-alliance.org/co…
1
4
10
578
Gantier Lab retweeted
27 Oct 2023
Our latest work, out today in @PLOSBiology suggests that not only do mammalian cells absorb bacteriophages, but they appear to use them as a resource to enhance growth!
journals.plos.org/plosbiolog…
This work was led by @marion_bichet and out on World Phage Week! #WorldPhageWeek
7
79
278
29,359
Gantier Lab retweeted
24 Oct 2023
(2/2) Talks from: @ShaliniChelliah (@elaine_sanij lab, @SVIResearch), @QiZhang85 (@MonashBDI), @eric_kusnadi (@PeterMacCC), Steve Rockman (@CSL) and Cameron Stuart (@CSIRO).
@traude_beilharz
@GantierLab
@ClarksysCorner
@nadia_davidson
@jacki_hf
@EMBLAustralia
7
10
841
Gantier Lab retweeted
24 Oct 2023
RNA Victoria meeting: Dec 5, 2023, at @MonashUni.
Program & FREE registration: rnavic.com
🙏RT! #RNAvic
1
17
11
2,775
Gantier Lab retweeted
23 Oct 2023
Noxopharm’s Dr Olivier Laczka and Associate Professor Michael Gantier from @Hudson_Research are currently showcasing the team’s latest breakthroughs at the Oligonucleotide Therapeutics Society Annual Meeting in Barcelona.
#biotech #Innovation #mRNA
2
10
311
22 Oct 2023
Great talk from Arwaf Alharbi about her PhD studies on how gapmer ASOs modulate TLR7/8 sensing at the OTS 2023 meeting!
8
545