Respiratory 🫁 doctor. Specialist interest in asthma
Joined January 2013
- Tweets 6,566
- Following 517
- Followers 1,846
- Likes 10,032
335 Photos and videos
Pinned Tweet
26 May 2021
Tweetorial for UK docs using @CernerUK PowerChart (not sure if this format will be useful but here goes)
First a question: how would you rate yourself as a PowerChart user?
19%
Basic
40%
Average
36%
Better than average
5%
Expert
171 votes • Final results
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Hugo Farne 🫁 retweeted
This study validates a previously reported bronchial signature of bronchiectasis in nasal epithelium. Changes in gene expression and cell-type composition associated with radiological bronchiectasis are similar across both bronchial and nasal epithelia. bit.ly/4qgq7SO
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Hugo Farne 🫁 retweeted
European Respiratory Journal: TSC2 mutations are the main cause of sporadic LAM in nearly all patients bit.ly/4rZoqtJ
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Hugo Farne 🫁 retweeted
May 3
Inhaled anti-TSLP for persistent asthma -Phase 1 study
linkinghub.elsevier.com/retr…
AZD8630 well tolerated with low incidence of ADA
Suppression of FeNO indicating effects on airway epithelial cells and downstream IL13 signalling
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Hugo Farne 🫁 retweeted
Excited to share our ‘Evolutionary characterization of #LungCancer metastasis’ in #TRACERx & #PEACE, published today in @Nature: a decade spanning effort led by the Jamal-Hanjani lab, @SwantonLab, @NickyMcGranahan & @ZaccaSimo at @uclcancer & @TheCrick. Link below
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Hugo Farne 🫁 retweeted
Apr 25
A study 10 years in the making, just published in @LancetRespirMed
How do DPP1 inhibitors really work in bronchiectasis?
We show a novel mechanism for treatment efficacy, by inhibiting Azurocidin-1, a ciliotoxin, DPP1i can enhance mucociliary clearance.
thelancet.com/journals/lanre…
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Hugo Farne 🫁 retweeted
Apr 18
ECCMID 2026
No induction of resistance over 6 months with monoclonal antibody therapy against pseudomonas in bronchiectasis
Encouraging beneficial changes to the microbiome too
Encouraging early results presented by @beccahull_
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Hugo Farne 🫁 retweeted
Inhaled immunoglobulin as a novel treatment for bronchiectasis: results from a phase 1 trial
Inhaled immunoglobulin G was associated with low rates of adverse events and reduced airway bacterial burden. Encouraging results! Online now at @ATSBlueEditor
academic.oup.com/ajrccm/adva…
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Hugo Farne 🫁 retweeted
People often ask how breakthroughs occur in cancer biology-often the story is more complex - the survival plot for myeloma outcomes is extraordinary - improvements come about in incremental steps - in my lifetime treatment of Myeloma has almost transformed into a curable disease
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Hugo Farne 🫁 retweeted
Apr 4
No cigar for Rilzabrutinib (BTK inhibitor) in mod-sev asthma (Ph 2)
Futility on primary EP of loss of asthma control upon withdawal of ICS/LABA
thelancet.com/journals/lanre…
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Apr 2
It makes no sense to me to close roads and dig them up just before a 4 day bank holiday with the disruption inevitably being extended by 4 more days?
@MayorofLondon can you make it prohibitively expensive to do this?
@CadentGasLtd @UKPowerNetworks @thameswater
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Mar 31
@DHSCgovuk @wesstreeting
Resident doctor strikes have highlighted all sorts of issues.
Not least the inefficient process to sign up to the bank to locum. Why do occupational health checks have to be in person? And why can’t in person ID checks be at the nearest hospital HR?
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Mar 31
I suspect it is easier signing up for locum agencies - which are more costly for Trusts and by extension, taxpayers.
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Jan 25
This data from the charity @asthmalunguk was kindly highlighted to the public by @tobithomas_ and @guardian.
Asthma and COPD remain common and major causes of ill health and death both in the UK and globally, yet both are underfunded (especially COPD).
Jan 23
“A stark and avoidable injustice in respiratory health” ⚖️
This, in the words of @HugoResp, is the situation laid bare by a recent analysis of NHS admissions data by @asthmalunguk 🫁
Dr Farne was interviewed as part of @guardian coverage of the study: theguardian.com/society/2025…
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Hugo Farne 🫁 retweeted
Jan 23
“A stark and avoidable injustice in respiratory health” ⚖️
This, in the words of @HugoResp, is the situation laid bare by a recent analysis of NHS admissions data by @asthmalunguk 🫁
Dr Farne was interviewed as part of @guardian coverage of the study: theguardian.com/society/2025…
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Hugo Farne 🫁 retweeted
We have a one year clinical fellow post (maternity cover) available. Study looking at human viral challenge in bronchiectasis. Would suit IMT or specialist respiratory trainee. Details: imperial.ac.uk/jobs/search-j… Grateful for retweets. Please DM/email if interested.
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29 Dec 2025
@AmazonHelp @AmazonAlexa Disappointed that an Echo Show I gifted my sister for Christmas mainly for the drop in function (to use with my ageing not tech savvy parents and my young kids with no phones) does not support drop in currently. They’ve now unplugged it ☹️
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29 Dec 2025
They were sceptical about its usefulness as “it doesn’t do anything you can’t do with a phone” - but “drop in” is different.
Would appreciate an update when the software fix is ready so I can tell them to plug it back in.
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Hugo Farne 🫁 retweeted
19 Dec 2025
Restricting access to suicide methods is one of the best evidenced approaches to prevention.
Barriers on bridges, limits on paracetamol & in developing countries, a ban on pesticides.
New review by my Manchester colleagues & friends. 1st author @SarahESteeg
15 Dec 2025
📢 New Research 👇🏼
Does restricting access to lethal means prevent suicide?
An umbrella review in @BMJMentalHealth finds strong evidence for physical barriers, pesticide bans & reduced paracetamol pack sizes, though study quality varies & LMIC data are scarce.
Read more 👇🏼 mentalhealth.bmj.com/content…
#SuicidePrevention #PublicHealth #MentalHealth #MeansRestriction
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Hugo Farne 🫁 retweeted
21 Dec 2025
Really coool. And very relevant to Pulmonary Fibrosis
#ScienceMatters
#CurePF4All
science.org/doi/10.1126/scie…
H/T @HaoYin20
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6 Jul 2023
@TfL @ImperialNHS @imperialcollege @ImperialNHLI @ImperialCharity
0.6 miles / 13 min walk from the nearest Santander Cycle stop to Hammersmith / Queen Charlotte Hospital & Imperial College’s site there.
Lots of staff!
Any chance of a stop on site?
Help us exercise!
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10 Dec 2025
The nearest stop (junction of Wood Lane and Westway) has been closed for 3 weeks to re-lay paving slabs. This has added yet another 10mins to my commute! Another reason for a stop closer to the Hammersmith Hospital campus.
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5 Sep 2025
@CityWestminster @limebike @TfL
Ongoing problem with Lime bikes obstructing TfL cycle docks on South Wharf Road.
I report as often as I can and have time.
Please consider making this a “no parking” zone for Lime bikes obstructing TfL /- creating a dedicated space for them.
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11 Sep 2025
Worse today - last day of tube strikes.
I can only report 5 of these.
When will you make this a non parking zone @limebike?
When will you create an e-bike parking area @CityWestminster?
Disruptive for @ImperialNHS
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