Type IV Pilus | Aspiring e- cryo-microscopist | PhD Candidate | UofToronto | P. Lynne Howell lab 🇨🇦🔬🦠
Joined March 2022
- Tweets 236
- Following 211
- Followers 90
- Likes 156
17 Photos and videos
Ian Yen retweeted
18 Nov 2024
Excited to share our new book chapter! We summarize recent advances in the structures and mechanisms of non-fimbrial adhesins in biofilm formation, with perspectives on upcoming discoveries in this field. #BiofilmResearch #Adhesins
link.springer.com/chapter/10…
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Ian Yen retweeted
18 Nov 2024
Just in time for #WAAW, collab with the Strynadka lab @UBC - Cryo-EM characterization of the anydromuropeptide permease AmpG central to bacterial fitness and β-lactam antibiotic resistance. @McMasterIIDR @BBS_McMasterU #AMR nature.com/articles/s41467-0…
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Ian Yen retweeted
7 Nov 2024
Our new review on regulation of #T4P type IV pilus assembly #buildingpermits, by PhD candidate Nathan Roberge, is now available for you to enjoy with your morning coffee! 😀 @McMasterIIDR @BBS_McMasterU @MacGlobalNexus @machealthsci
journals.asm.org/doi/epub/10…
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Ian Yen retweeted
30 Oct 2024
Happy and proud to see this paper online! We resolved the in-situ architecture of the P. aeruginosa Type IV pilus machine and discovered the localisation and role of PilY1. Great collaboration with @JunLiuLab @Dr_Lori_Burrows @BrunLabCaulo @PLynneHowell . nature.com/articles/s41467-0…
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Happy to share my first PhD paper from @PLynneHowell lab with my fantastic post-doc mentor @gregbwhitfield from @BrunLabCaulo as well as @Dr_Lori_Burrows and @RubinsteinJohn with #cryoem support where we propose how the bifunctional Tad pilus motor works🧵 biorxiv.org/content/10.1101/…
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14/ I would also like to acknowledge a complementary study from Harry Low's lab, where they propose a different CpaF catalytic mechanism.
nature.com/articles/s41467-0…
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15/ Many thanks to members of my lab for their tremendous support and to @RubinsteinJohn lab members (@think_zesty, @CourbonGautier, @hanlinw222, Hui Guo, @JustinDiTrani, @SBenlekbir, Zhijie Li) for teaching me #cryoem from scratch.
Happy reading!
biorxiv.org/content/10.1101/…
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Ian Yen retweeted
10 Sep 2024
1/ #CryoSPARC v4.6 is out! 🚀Up to 2.1x faster refinements and classification, a new job tree view that is scalable and performant on large #cryoEM projects, job groups, new cards and table view, automatic inspect picks, and more!
cryosparc.com/updates
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