Cell biologist, geneticist and fascinated by all things science 🦠 šŸ”¬ . @CZIScience program officer leading single cell tech & supporting @humancellatlas

Joined July 2017
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Jonah Cool retweeted
AI has transformed how we design therapeutics. But targeted delivery is still an expensive guessing game. Today @BobbyHollings and I are launching @deliverome with @beckypferdehirt and @radialscience at @AsteraInstitute, to fix that. 🧵
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Jonah Cool retweeted
8 Nov 2025
Train and submit your model predictions for the OpenADMET Expansion challenge!! Lots of submissions already rolling in. Check out the webinar from @wpwalters, @barrybunin @huggingface et al for more info youtube.com/watch?v=9v0Ej_FL…
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Jonah Cool retweeted
Today @AnthropicAI released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been a game changer—like having a supercharged research assistant. Here are 6 prompts that will transform how you search the literature. A 🧵
20 Oct 2025
We’re building tools to support research in the life sciences, from early discovery through to commercialization. With Claude for Life Sciences, we’ve added connectors to scientific tools, Skills, and new partnerships to make Claude more useful for scientific work.
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Jonah Cool retweeted
A scientist's guide to AI agents — how could they help your research? @Nature šŸ‘‰ nature.com/articles/d41586-0… Enjoyed discussing this with @LizzieGibney. Great to see @ScientistTools featured, along with several ongoing projects in our group. AI agents can accelerate discovery, but their true scientific value depends on how we evaluate and test them, an open challenge for the field
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Jonah Cool retweeted
Deadline extended to May 25! ā³Consider submitting your recent work to the Generative AI and Biology workshop at @icmlconf
ā° Deadline extended to May 25th for GenAI and Biology workshop, considering multiple requests & NeurIPS deadline! šŸš€Recent submissions to NeurIPS & other conferences/journals are welcome! 🧬For amazing speakers and more details: genbio-workshop.github.io/20…
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Jonah Cool retweeted
It’s time again for Cell Biology at Scale (CB@S), an annual gathering for researchers from diverse disciplines to share ideas on how new technologies can transform #cellbiology! Co-hosted by #CZBiohubNY & @ChanZuckerberg. Learn more and register: czbiohub.org/events/cell-bio…
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Jonah Cool retweeted
16 Apr 2025
1/ The Chan Zuckerberg Initiative @cziscience is now hosting our AIDO.Cell-100M in its virtual cells platform. 🧬🦠
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Jonah Cool retweeted
Big Network news! #CZBiohubSF #CZImagingInstitute will join forces to form a new Biohub aimed at developing groundbreaking imaging technologies to observe, measure, and understand biology like never before. Learn more: czi.co/43W0LBO
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Jonah Cool retweeted
8 Feb 2025
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases. I'm trying to understand non-surgical chemo and targeted therapy options, new pathology markers to better diagnose subtypes/treatments, and any data on progression in pediatric patients. Please feel free to share – I’m trying to cast a wide net due to the rarity of this condition and how little is known. People can contact me directly at my first name (as written in my profile) at octant.bio.
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Very excited about this project as a model for partnership, opportunity to open up new fields of biology, and the provide critical data that advance models toward fundamental questions in cell biology. Stay tuned for progress!!!
6 Feb 2025
ā€œThe Billion Cells Project will help clarify our understanding of the fundamental biology underpinning human health disease while supercharging efforts at the intersection of AI & biology.ā€ - @JCoolScience Learn more about the project czi.co/4hBZ5kM
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CZI recently announced an innovative new opportunity for GPU access. It's an exciting approach specifically aimed at supporting bold and ambitious problems that are bottlenecked on compute. Have a look and please apply or encourage others to do so! chanzuckerberg.com/rfa/ai-co…
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The @humancellatlas package in @Nature is a bright spot for me as we move toward the end of the year. I'm late to the party and really enjoyed watching all the buzz last weekšŸŽ†! Congrats to all involvedšŸ‘ The weekend allowed reflection on a few personal areas of excitement 🧵1/6
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5/6 the papers in the package on ethics and equity shared a lot of work and thinking on best practices that can be generalized. More focus on engagement and inclusion are necessary for robust science and paving the way for future collaboration models.
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6/6 the future is šŸ˜Ž. Like great science efforts, the questions and technology opportunities outpace the immediate learnings. Looking across our grantee communities and internal roadmaps has me filled with excitement. Can't wait for the next waves of data, tech & models.
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Jonah Cool retweeted
Pleased to share that our #earlyAIR cross-tissue, age-specific, #flowcytometry reference of immune cells from five tissues of the pediatric #airway is now published in @jacionline. jacionline.org/article/S0091… @cziscience @MCRI_for_kids @UniMelbMDHS @RCHMelbourne
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Incredibly exciting and important work. Studies like this are pushing the limits of functional screen and absolutely represent a beacon for work in the years to come. Can't wait! Also, the liver is amazing:)
In collaboration with Reuben Saunders, @JswLab, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue. Check it out! biorxiv.org/content/10.1101/…
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Jonah Cool retweeted
In collaboration with Reuben Saunders, @JswLab, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue. Check it out! biorxiv.org/content/10.1101/…
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