Haematologist & Postdoc @TheDawsonLab @PeterMacCC // Immunotherapy resistance in acute leukaemia and lymphoma
Joined August 2011
- Tweets 131
- Following 821
- Followers 214
- Likes 1,488
6 Photos and videos
Jamie Kuzich retweeted
Apr 15
How does a cell learn? In our new perspective in @Nature we propose a model where the properties of the AP-1 family of transcription factors – stress-induced feedback, regulatory combinatorics & cellular memory – encode a mechanism for cellular learning. nature.com/articles/s41586-0…
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Jamie Kuzich retweeted
28 Nov 2024
CART could have it ALL.
Obe-cel results @NEJM:
👉127 pts
👉complete remission 55%
👉median event-free survival 12 months
👉1-year survival 65%
👉severe CRS/ICANS in 2% and 7%
👉survival curve plateau but limited follow-up
👉high tumor burden still a challenge
Congrats @drclaireroddie @hemedoc and colleagues!
nejm.org/doi/full/10.1056/NE…
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Jamie Kuzich retweeted
26 Nov 2024
Bridging RT v systemic tx retrospective before axi-cel #ASH24:
- 98 pts, 35 RT bridging alone
- CR 85% RT, 71% chemo (not significant)
- 1-yr PFS 75% RT, 49% chemo (significant)
- MV model PFS: improved PFS (HR 0.41) with RT alone
Time for a randomized trial. #lymsm
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Jamie Kuzich retweeted
30 Oct 2024
7:30: Declare big day of writing
8:00-17:00: Fail to write
17:30: Declare big day of writing tomorrow
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Jamie Kuzich retweeted
21 Oct 2024
Gonna get a tattoo on my chest that reads "just because a result is statistically significant does not mean it is biologically significant" & a matching tattoo on my back that reads "just because a result is biologically significant does not mean it is statistically significant"
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Jamie Kuzich retweeted
26 Sep 2024
Focal deletions of noncoding regions in cancer genomes can have unexpected consequences. Out now in @BloodJournal, we’ve discovered an intriguing mechanism of oncogene activation whereby focal deletion of a ‘promoter tether’ leads to aberrant expression of IRX3 in T-ALL. Thread👇
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Jamie Kuzich retweeted
2 Sep 2024
Dr Jamie Kuzich (@JantonKay) from @TheDawsonLab has received the @ASH_hematology 2024 Global #Research Award - one of just of 11 awarded to early career investigators from around the globe.
Watch 👇Read more: petermac.org/about-us/news-a…
#bloodcancer #hematology #haematology
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Jamie Kuzich retweeted
7 Aug 2024
Last month, the Dawson Lab celebrated our 10th year in action! 🎉
It was a wonderful day of laughs, catching up, and reflecting on just how far we’ve come over the last decade.
What a great looking group!
See ya in 5 years! 🥂
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21 May 2024
So good to finally see this out in all its glory. I remember @charles_bell92 first telling me about this system on the drive down to lab retreat in my first few weeks in the lab, and it was beautiful to see the story develop. Bravo, Charlie!
20 May 2024
Cofactors are a crucial part of the gene activation process. Yet, we still don't have a comprehensive understanding of how and why they are used by different genes. Proud to present our attempt to address this key question, now published
nature.com/articles/s41588-0…
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Jamie Kuzich retweeted
26 Apr 2024
Proud to see our paper describing BARtab and bartools, two integrated software tools for the analysis of synthetic cellular barcodes is now published @CellRepMethods! We hope the community finds this work useful.
cell.com/cell-reports-method…
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Jamie Kuzich retweeted
25 Apr 2024
Our latest paper from @TheDawsonLab - huge congratulations to @HenriettaHolze & @DaneVass who led this work - hope the lineage tracing / barcoding community find this helpful cell.com/cell-reports-method…
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Jamie Kuzich retweeted
11 Apr 2024
How to pick a problem. Today in @CellCellPress. 1/53
cell.com/cell/fulltext/S0092…
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Jamie Kuzich retweeted
29 Mar 2024
When the results you've been excited about for 2 years turn out to be an artifact
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Jamie Kuzich retweeted
29 Mar 2024
Stellar 2024 Lab retreat with the best people! Ready for the year ahead! ⭐️ #DawsonOpen🎾
#unitedinnovation #boundlessdiscovery
#bigimpact
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Jamie Kuzich retweeted
28 Mar 2024
What a PERFFect day to share our new preprint!
With @tsion_abay #BobStickels @MerilTakizawa @ChaligneRonan and @Satpathology, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. biorxiv.org/content/10.1101/… 1/n
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Jamie Kuzich retweeted
25 Mar 2024
me on my way to annoy my lab mates instead of writing this abstract
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Jamie Kuzich retweeted
11 Mar 2024
Reminds me of what Brenner said about differentiation in Loose Ends (@CurrentBiology).
cell.com/current-biology/pdf…
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Jamie Kuzich retweeted
3 Mar 2024
We’re hiring 2x bioinformatics/computational biology RA’s in @MAF_Dawson’s lab in Melbourne!
You’ll be working on all things single-cell and harnessing the power of our SPLINTR lineage tracing tool!
careers.petermac.org/job/MEL…
Please share with your network☺️
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