@KlippLindingLab profile picture
Klipp-Linding Laboratory @KlippLindingLab

Researching Biological Systems in Time, Space and Disease. klipp-linding.science

Joined April 2018
  • Tweets 73
  • Following 73
  • Followers 91
12 Photos and videos
Klipp-Linding Laboratory retweeted
nature
@Nature
Mar 10
For the first time, researchers have simulated nearly every chemical reaction in a living bacterial cell go.nature.com/46UnkYp

‘Virtual cell’ captures the most-basic process of life: bacterial division

Nature - Researchers simulated nearly every molecule in a bacterial cell —and then watched it grow and reproduce.

nature.com
19
227
993
76,300
Klipp-Linding Laboratory retweeted
Nature Biotechnology
@NatureBiotech
25 Nov 2025
Biomacromolecules are delivered across the blood–brain barrier when administered systemically go.nature.com/412exBi rdcu.be/eRyTm

1
29
97
11,570
Klipp-Linding Laboratory retweeted
Prof(ret.) Dr Rune Linding @RuneLinding
8 Dec 2024
Universal differential equations for systems biology: Current state and open problems biorxiv.org/content/10.1101/…

Universal differential equations for systems biology: Current state and open problems

Universal Differential Equations (UDEs) combine mechanistic differential equations with data-driven artificial neural networks, forming a flexible framework for modelling complex biological systems....

biorxiv.org
1
2
97
Klipp-Linding Laboratory retweeted
ECCB2026 Geneva, Switzerland@ECCBinfo
14 Oct 2024
🔍 How can #bioinformatics enhance #AI in #lifesciences? Prof. Peer Bork, Director of @EMBLHeidelberg, shares his insights, and discusses the need for data infrastructure collaboration to drive innovation. 🎥 Watch the video, recorded at #ECCB2024 👇 @BorkLab
2:20
7
19
1,646
Klipp-Linding Laboratory retweeted
Carlos García@carlosg91018370
12 Jun 2023
🎉Exciting news! The @Icy_BioImaging team, along with @deepImageJ, is thrilled to announce the release of the 𝗝𝗮𝘃𝗮 𝗗𝗲𝗲𝗽 𝗟𝗲𝗮𝗿𝗻𝗶𝗻𝗴 𝗟𝗶𝗯𝗿𝗮𝗿𝘆 (𝗝𝗗𝗟𝗟), the new open source core library for #DeepLearning model inference in imaging! 🤖
2
37
108
41,063
Klipp-Linding Laboratory retweeted
Turk Lab@benturklab
8 May 2023
Early registration deadline is Wednesday! Please join us for this exciting conference! asbmb.org/meetings-events/mo…

Motifs, modules, networks: Assembly and organization of regulatory signaling systems

July 11–14, 2023 | Potomac, Md.

asbmb.org
6
9
3,225
Klipp-Linding Laboratory retweeted
Turk Lab@benturklab
12 Jan 2023
Truly excited that our collaboration with @CantleyLab and @LabYaffe, led by the mighty Jared Johnson and the unstoppable @Tomer_M_Yaron, to map substrate motifs for the Ser/Thr kinome is now out! Literally a project that spanned decades. nature.com/articles/s41586-0…

3
21
87
7,771
Klipp-Linding Laboratory retweeted
nature
@Nature
12 Jan 2023
Nature research paper: An atlas of substrate specificities for the human serine/threonine kinome go.nature.com/3GC1734

An atlas of substrate specificities for the human serine/threonine kinome

Nature - Analysis of the kinase activity of 300 protein Ser/Thr kinases reveals that the substrate specificity of the kinome is substantially more diverse than expected and is driven extensively by...

nature.com
8
36
21,008
Klipp-Linding Laboratory retweeted
Prof(ret.) Dr Rune Linding @RuneLinding
8 Jun 2022
Please RT/share
1
7
6
Klipp-Linding Laboratory retweeted
Prof(ret.) Dr Rune Linding @RuneLinding
8 Jun 2022
Conference Website icsb2022.berlin Abstract Submission Now Open - easychair.org/conferences/?c…
2
2
Klipp-Linding Laboratory retweeted
COMBINE@combine_coord
28 May 2022
Join us October 6-8, 2022 for #COMBINE2022! Co-located with #ICSB2022. In Berlin (Germany). COMBINE Community meet-up Oct 6-7, 9a.m.-6p.m ** COMBINE Forum Oct 8, 8a.m.-1:30p.m. Details and Call for papers to come. Be on the look out!
8
13
A global atlas of substrate specificities for the human serine/threonine kinome biorxiv.org/content/10.1101/…
1
2
Deep Hidden Physics Modeling of Cell Signaling Networks - Rune Linding youtu.be/DxYfnHbtr9s
1
2
Shapes of Cell Signaling sciencedirect.com/science/ar…
1
2
NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in pluripotent stem cells | Disease Models & Mechanisms | The Company of Biologists journals.biologists.com/dmm/…

NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CAH1047R homozygosity in...

Summary: Transcriptomic and proteomic analyses of iPSCs with allele-dose dependent expression of the PIK3CAH1047R oncogene confirm network rewiring in homozygous mutants, with self-sustained stemness...

journals.biologists.com
1
Klipp-Linding Laboratory retweeted
Rewire Therapeutics|Tx@Rewire_Tx
15 Jun 2021
Deep Hidden Physics Modeling of Cell Signaling Networks eurekaselect.com/194063/arti…
2
3
Klipp-Linding Laboratory retweeted
Kresten Lindorff-Larsen@LindorffLarsen
11 May 2021
Simone performed as series of independent simulations from different parts of the landscape to characterise the binding mechanism and minima. We isolate a transition state btw intermediate and bound state, but suggest that binding overall is limited by an entropic barrier. 3/4
1
2
6
Klipp-Linding Laboratory retweeted
Kresten Lindorff-Larsen@LindorffLarsen
11 May 2021
Happy to share a new preprint by @simo_bolognini on the transient exposure of a buried phosphorylation site in an autoinhibited protein. He used metadynamics and unbiased MD to examine how the inhibitory module folds upon binding to the Vav1 DH domain. 1/4 biorxiv.org/content/10.1101/…
2
8
65
Klipp-Linding Laboratory retweeted
Edda Klipp@EddaKlipp
6 Feb 2021
Open schools! Given current vaccination strategies (yellow) and low vacc levels, closed schools (gray) cause no significant drop of infections, no reduction in deaths or ICU demand, no prevention of next wave, our model shows. Focus on masks/distancing and fast broad vaccination!
1
3
9
Klipp-Linding Laboratory retweeted
Cell Reports@CellReports
21 Jan 2021
Deep neural networks identify signaling mechanisms of ErbB-family drug resistance from a continuous cell morphology space bit.ly/3c3lQiL

1
2
5
Load more