Joined November 2018
- Tweets 56
- Following 295
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6 Photos and videos
Chao Li Lab retweeted
Jun 4
Final version of this work has appeared today in @ScienceMagazine : science.org/doi/epdf/10.1126…
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May 18
Our latest work shows how modern total synthesis can enable therapeutically meaningful discovery, uncovering selective anti-C. difficile activity and toxin-protective effects of structurally complex polyether ionophores. Now available on ChemRxiv: chemrxiv.org/doi/full/10.264…
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May 1
One step. Two C–C bonds. Three natural product syntheses. Our auto-tandem catalytic cascade for natural product synthesis is out today in JACS!pubs.acs.org/doi/10.1021/jac…
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Chao Li Lab retweeted
14 Oct 2025
Ambiphilic cross-coupling.
chemrxiv.org/engage/chemrxiv…
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Feb 28
First total synthesis of paulomycin A — now in JACS. Rare sugar. Real synthetic challenge. Now accessible.pubs.acs.org/doi/10.1021/jac…
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Chao Li Lab retweeted
23 Nov 2025
Cobalt-Catalyzed Photoelectrochemical Dehydration of Primary Alcohols | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…
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Chao Li Lab retweeted
20 Nov 2025
Radical Retrosynthesis of Natural Products Enabled by Iron-based Reductive Olefin Coupling. Published today in @ChemRxiv : chemrxiv.org/engage/chemrxiv…
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7 Oct 2025
Our Chem. Soc. Rev. Article!
Radical Retrosynthesis: A Powerful Strategy for Modern Assembly of Terpenoid Natural Products.
Modern radical chemistry—MHAT, RAE, XEC, photoredox, HAT—reshapes retrosynthetic logic for complex terpenoids.
pubs.rsc.org/en/content/arti…
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5 Feb 2025
Thrilled to share our progress on the synthesis of highly oxidized DMOA-derived meroterpenoids—now out in JACS:pubs.acs.org/doi/10.1021/jac…! The unexpected reaction we stumbled upon in the final step turned out to be especially fascinating.
4 Feb 2025
#TotalSynthesis of DMOA-Derived Meroterpenoids: Achieving Selectivity in the Synthesis of ( )-Berkeleyacetal D and ( )-Peniciacetal I by Jianpeng Zhang, Xiaotong Luo, Jingfu Zhang, and Chao Li @LabChao in @J_A_C_S pubs.acs.org/doi/10.1021/jac…
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Chao Li Lab retweeted
7 Nov 2024
Establishing the Comprehensive Structure-Activity Relationship of the Natural Antibiotic Kibdelomycin/Amycolamicin (Chao Li and co-workers) @LabChao onlinelibrary.wiley.com/doi/…
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2 Oct 2024
We're excited to have achieved a structure-activity relationship analysis of the complex natural antibiotics Kibdelomycin/Amycolamicin through total synthesis. We hope this work will contribute to the development of new antibiotic therapies. onlinelibrary.wiley.com/doi/…
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Chao Li Lab retweeted
20 Sep 2023
The final version of this study was published today in @Nature : nature.com/articles/s41586-0…
19 Jan 2023
Today we report in @ChemRxiv a scalable solution to the total synthesis (and structural reassignment) of the Portimines (bit.ly/3iJ61DT). In collaboration with @_chrisgparker_ and Luke Lairson the remarkable biological activity of this natural product family was revealed
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Chao Li Lab retweeted
11 Aug 2023
Excited to share our latest paper on the total synthesis of Illicium sesquiterpenes. Not only access more targets but synthetically connect distinct molecular architectures of different subfamilies through late-stage skeletal reorganization triggered by Lewis acids or oxidants.
11 Aug 2023
Divergent Total Syntheses of Illicium Sesquiterpenes through Late-Stage Skeletal Reorganization | Journal of the American Chemical Society @CHNSci @TotalSynthesis @TotalSyntheses #Divergent #TotalSynthesis #sesquiterpenes #Rearrangement #LateStage pubs.acs.org/doi/10.1021/jac…
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Chao Li Lab retweeted
18 May 2023
Nickel-Catalyzed C-I-Selective C(sp2)-C(sp3) Cross-Electrophile Coupling of Bromo(iodo)arenes with Alkyl Bromides (Chao Li and co-workers) @LabChao onlinelibrary.wiley.com/doi/…
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8 May 2023
Hopefully, this recent work from our group will help some medicinal chemists. A general C(sp2)–I selective C(sp2)–C(sp3) cross-electrophile coupling.
onlinelibrary.wiley.com/doi/…
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Chao Li Lab retweeted
6 Apr 2023
Modern alchemy appearing today in @ScienceMagazine : science.org/doi/10.1126/scie…
Commentary (thank you Prof. Ye!): science.org/doi/10.1126/scie…
27 Oct 2022
Modern Alchemy with rAP. Appearing today in @ChemRxiv is a solution to the longstanding (>100 year) challenge of extending the scope of the original Kolbe reaction beyond simple hydrocarbons bearing no functional groups: bit.ly/3sBQ5Ve
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Chao Li Lab retweeted
19 Jan 2023
Today we report in @ChemRxiv a scalable solution to the total synthesis (and structural reassignment) of the Portimines (bit.ly/3iJ61DT). In collaboration with @_chrisgparker_ and Luke Lairson the remarkable biological activity of this natural product family was revealed
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Chao Li Lab retweeted
24 Oct 2022
Please check out our total synthesis of (−)-Peyssonnoside A @J_A_C_S. Big congratulations to Bo @BoXu44807071 and Chang!
Catalysis-Enabled 13-Step Total Synthesis of (−)-Peyssonnoside A pubs.acs.org/doi/10.1021/jac…
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Chao Li Lab retweeted
21 Sep 2022
Congratulations to chemist Prof. Phil Baran, who has been awarded the 2022 Danisco Foundation Science Excellence Award from @IFF. Baran is recognized for advancing science and technology relevant to the future of food, nutrition, and health magazine.scripps.edu/awards-… @BaranLabReads
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Chao Li Lab retweeted
15 Sep 2022
Final version of this study was published today in @J_A_C_S : bit.ly/3QGPDhP
27 May 2022
Simple, practical, and broadly applicable. Next generation decarboxylative arylation, appearing today in @ChemRxiv : bit.ly/3z6Ko5Y
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