All about enveloped #viruses and other #ExtracellularVesicles as well as extracellular RNA #exRNA

Joined March 2020
41 Photos and videos
LabWitwer retweeted
Grant terminations have grabbed the headlines and have seen legal action, but even more damaging to the US research enterprise has been the massive decrease in research grants issued by federal agencies NIH: -57% in the number of awards and -63% in value compared to FY24
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LabWitwer retweeted
At the next #EVClub with #EViNS, Hermine Counil presents "Brain penetration of peripheral #ExtracellularVesicles from #Alzheimer's patients and induction of #microglia activation" Wed July 16, 12 noon EDT/18.00 CEST/midnight Beijing Need the login? surveymonkey.com/r/EVClubISE… isevjournals.onlinelibrary.w… Can't join the call? Recording available ASAP on the ISEV YouTube channel: youtube.com/c/ExtracellularV… @ISEV_Journals @LabWitwer
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LabWitwer retweeted
18 Jun 2025
Excited to try out our new Ascent automated SEC instrument from @everestbiolabs here in the @LabWitwer @KennethWWitwer #ExtracellularVesicles
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LabWitwer retweeted
Although #ExtracellularVesicles have strong promise in #LiquidBiopsy, EVs from specific sources can be difficult to find, like a needle in a haystack. In this #EVClub, Agustin Enciso-Martinez et al present a solution they have found and validated in pancreatic adenocarcinoma. When? Wed July 2, 12 noon EDT/18.00 CEST Need the login? surveymonkey.com/r/EVClubISE… See: isevjournals.onlinelibrary.w… Can't join the call? The recording will available ASAP on the ISEV YouTube channel: youtube.com/c/ExtracellularV…
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LabWitwer retweeted
Engineering #ExtracellularVesicles for Efficient Delivery of Therapeutics and Genome Editors At the next #EVClub, Xiuming Liang presents recent J Controlled Release and Nature Communications papers from the @SamirAndaloussi group Wed June 4, 12 noon EDT/18.00 CEST Need the login? surveymonkey.com/r/EVClubISE… Archive available ASAP on the ISEV YouTube channel: youtube.com/c/ExtracellularV… @IsevOrg @LabWitwer @NatureComms #ISEV
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LabWitwer retweeted
At the next #EVClub, Silvia Cappello addresses molecular cues trafficked by #ExtracellularVesicles during human brain development pubmed.ncbi.nlm.nih.gov/3930… Wed March 19 12 noon EST/17.00 CET Need the login? surveymonkey.com/r/EVClubISE… Moderated by Tsuneya Ikezu and #EViNS, the Extracellular Vesicles in Nervous Systems Special Interest Group of #ISEV Can't join the call? The recording will available ASAP on the ISEV YouTube channel: youtube.com/c/ExtracellularV… @IsevOrg @LabWitwer
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LabWitwer retweeted
At the next #EVClub, Joseph Brealey shines "a light on fluorescent EV dyes: Evaluating efficacy, specificity and suitability by nano-flow cytometry" isevjournals.onlinelibrary.w… Wednesday, Feb 26, 12 noon EST/18.00 CET Need the login? surveymonkey.com/r/EVClubISE… Can't join the call? The recording will available ASAP on the ISEV YouTube channel: youtube.com/c/ExtracellularV… @IsevOrg #ISEV #NFCM @LabWitwer @ISEV_JExBio @ISEV_Journals
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LabWitwer retweeted
This week's #EVClub is all about how #ExtracellularVesicles factor into #coagulation. We review "A century of evidence for highly coagulant tissue factor/activated factor VII complex-exposing EVs in body fluids" with Johannes Thaler, Carla Tripisciano, and Rienk Nieuwland. See also: doi.org/10.1182/blood.202402… and ashpublications.org/blood/ar… Wed 12 noon EST/18.00 CET Need the login? Sign up: surveymonkey.com/r/EVClubISE… @IsevOrg @LabWitwer
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LabWitwer retweeted
Great turnout for the January #EViNS #EVClub. Carla Lopes presenting her work on #iPSC-derived neuronal models of Huntington's disease and treatment with #ExtracellularVesicles thno.org/v13p3707.htm This will be archived at: youtube.com/c/ExtracellularV… To sign up for EVClub: surveymonkey.com/r/EVClubISE… #ISEV @IsevOrg @TsuneyaIkezu Christian Neri @LabWitwer
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LabWitwer retweeted
This week's #EVClub features an intriguing preprint on "Direct intercellular vesicle exchange between adjacent cells" biorxiv.org/content/10.1101/… With Jun Yamashita, Tomohiro Minakawa, and Mima Shikanai Wednesday Feb 19, 11 AM Japan, 10 AM Beijing, 1 PM Melbourne and Tuesday Feb 18, 9 PM EST Need the login? surveymonkey.com/r/EVClubISE… Archive available ASAP on the ISEV YouTube channel: youtube.com/c/ExtracellularV… @IsevOrg @LabWitwer and thanks to @Pluchinolab
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LabWitwer retweeted
ICYMI: #EVClub of #ISEV and #EViNS. Carla Lopes presents “#ExtracellularVesicles improve GABAergic transmission in Huntington's disease iPSC-derived neurons” (Theranostics, 2023) @IsevOrg youtu.be/c9oFoLy3xdU
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LabWitwer retweeted
An exciting next #EVClub with #GUSEV: identifying cell sources of #ExtracellularVesicles by transcriptome deconvolution @ISEV_Journals Per Svenningsen, Jannik Hjortshøj Larsen, Iben Skov Jensen Wednesday, December 18, 12 noon EST/1800 CET Need the login? surveymonkey.com/r/EVClubISE… moderation by @DSchnekenB @flscientist @CristinaGrange Can't join the call? The recording will available ASAP on the ISEV YouTube channel: youtube.com/c/ExtracellularV… doi.org/10.1002/jev2.12511 @IsevOrg @LabWitwer
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LabWitwer retweeted
At the next #EVClub, we learn from Carla Lopes about #ExtracellularVesicles and Huntington's disease #iPSC neurons thno.org/v13p3707.htm Wednesday, January 15, 12 noon EST/18.00 CET Need the login? surveymonkey.com/r/EVClubISE… A collaboration with #EVINS, the @IsevOrg special interest group on #EVs in Nervous Systems. Intro/moderation by @TsuneyaIkezu @Neri_lab thanks to @Pluchinolab for organizing Can't join the call? The recording will available ASAP on the ISEV YouTube channel youtube.com/c/ExtracellularV… #ISEV #HuntingtonsDisease @LabWitwer
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LabWitwer retweeted
10 Jan 2025
🖋️ Sharpen your pens! ✅ Submit your Late Breaking Abstract for #ISEV2025 between 13 January - 2 February! 🐤 ..and don't forget to register, Early Bird fees last until 3rd of March buff.ly/4cYmiKW @albers_eva @AnHendrix2 @editbuzas @LLanguino @LeeRetinaLab
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Announcing many Exciting Awards for Young Researchers at EVOLVE 2025!🏅🏅🏅 Do Register and Submit your Abstracts ASAP to be the winners! Indian Society for Extracellular Vesicles (InSEV) evolve2025.in
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LabWitwer retweeted
Excellent comment about core facilities. They add dimensions to research programs. You can train with world leaders in specific techniques or entirely hand over specific experiments, measurements, and analysis. The value added is not easily reduced to money, either.
Core facilities are truly one of the most undervalued assets in an academic institution. They are often treated as also rans, staffed by non tenured faculty with little leeway, and given an exceedingly short runway to become profitable. In an age of shrinking lab sizes and astronomical maintenance contracts, cores will increasingly become the engines that fuel research. Institutions have to invest in core facilities in order to spur innovation and efficiency, and expect some will be a “loss leader” on revenues, with intangible returns on research productivity. For those on the job market, getting to know the institutional core facilities and directors should be an indispensable part of the recruitment process. Talk one to one with some of the core directors. How institutions approach core facilities is a huge “tell” on institutional research ethos.
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LabWitwer retweeted
This #EVClub was with @ColinHisey, who presents: “Light-induced Extracellular Vesicle and Particle Adsorption (LEVA) Enables Tunable Micropatterning of EVs for Biomedical Applications” #ExtracellularVesicles @IsevOrg @Troymen11 @LabWitwer youtube.com/watch?v=Y_Mi2rPV…
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LabWitwer retweeted
20 Nov 2024
Replying to @EditBuzas
@EditBuzas gives a fascinating talk about a new ectosomal biogenesis pathway of small EVs/exosomes - linked to the autophagosome system! @LabWitwer EXCEL #EVCore education day
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LabWitwer retweeted
Aiden Jurcenko presents his MSE project on high-resolution characterization of #HIV virions and host #ExtracellularVesicles through “STORM-FISHing”. He’s presenting as part of our EVCore facility open house and education day. Really great work, Aiden! @LabWitwer
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This recent #EVClub was a double-header on new technologies for single-particle and single-molecule detection. 1. @ReateguiLab & Kim Truc Nguyen on "Integrated Antigenic and Nucleic Acid Detection in Single Virions and #ExtracellularVesicles with Viral Content" (onlinelibrary.wiley.com/doi/…) 2. Alexander Johnson-Buck & the @NilsWalterLab on novel single-molecule detection technologies. Would you like to join the EVClub mailing list? Sign up here: surveymonkey.com/r/EVClubISE… @IsevOrg @LabWitwer youtube.com/watch?v=LNCHeTiv…
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