The lab combines basic biology of stem cells and macrophages with translational approaches of cell therapy to develop novel forms of treatments

Joined March 2020
12 Photos and videos
Great work @BeziatV and colleagues
Out in @CellCellPress today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. cell.com/cell/fulltext/S0092…
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Thankful @ERC_Research to receive funding in the #ERCPoC funding scheme and my third ERC grant to further advance our #iPSC #macrophage pipeline to deliver macrophages directly into #lungs of #patients who suffer from bacterial airway infections. mhh.de/presse-news/neue-wege…
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Locked #Macrophages to enhance anti-tumor activity. #CARs can do so much and much more. Check our latest NN @NatImmunol. #cancer #immunity #cells #immunotherapy nature.com/articles/s41590-0…

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Fabulous study and sooo important. Thanks to the entire #family. We feel honored to have contributed to this outstanding work on #monocytes #macrophages, laying the foundation for new #treatments. congrats @BustamanteJaci1 @ALNeehus @casanova_lab and Bruce Trapnell from CCHMC.
1/ We are excited to report the discovery and mechanistic exploration of human AR complete CCR2 deficiency in @CellCellPress. Surprisingly, CCR2 deficiency underlies two narrow phenotypes: progressive polycystic lung disease and mycobacterial disease (sciencedirect.com/science/ar…).
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Training next gen #scientists in #stemcells science is of utmost importance. Thanks @killian_hurley @cost #training #ipsc #student
So good when you see a former graduate of @CReM_Boston spreading the Open Source gospel! Way to go @killian_hurley Lab @RCSI_Irl ! Keep sharing! #opensourcerules! #itsthecells! #helpisontheway! stemcellres.biomedcentral.co…
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#macrophages from human iPSC equipped with CARs, entering next generation #immunotherapies. New therapies for anti-#cancer and beyond. See paper below @jitcancer @ShifaaAbdin
New #JITC article: Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia bit.ly/479s0XI @LachmannLab @ShifaaAbdin
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#iPSC derived #macrophages and #science will be also #sexy in #2024. Nothing to add more. Thanks to the #team for the nice #gift 😂😇
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Thanks to the #team and #2024 we are ready for our #ChristmasDinner . Thanks also to all #supporters . #macrophage and #stemcells science rock. See u all and thaaaaank you so much
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#macrophages and #immune cells shape modern #therapies. We are part @ESGCT in Brussels introducing our latest work in several sessions. Come and join our team 👇
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Targeting alveolar #macrophages for future #Immunotherapy. Diseases of the #lung #infection #inflammation , the role of macrophages and new therapeutic concepts 👉 read more @jclinicalinvest and thanks @HeroldLab 👏 link here 👉jci.org/articles/view/170498…
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A „must have“ for all people which are dedicated to #macrophages. Thanks @lab_mass that we contribute to this nice work. Check out the original article below 👇
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This is for #macrophage lovers & those who just start to work on these fascinating cells! Thanks to all participating labs! @LabSchlitzer @FGinhoux @KC_DC_01 @GentekRebecca @DagmarWachten @SierraLabAch @KierdorfLab @ValerieWittamer @FNimmerjahn @BajenoffL link.springer.com/book/10.10…
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#research never sleeps. Thanks to the team, we are pampering our cells 24/7 as our #macrophages to not care for holidays and weekends. Dedicated to #patients and breakthrough research. Thanks to all supporters and families
Research never sleeps! But what happens during the summer vacations? Dr. Daniela Paasch @LachmannLab @MHH_life and Hannes Neubauer @mgalactus @TWINCOREtweets show us how it works. resist-cluster.de/en/researc…
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Gene and cell therapies using #macrophages to combat rare and common diseases. next generation #Immunotherapy that’s our mission. Congrats Liart and well deserved. @MHH_life @RESIST_cluster @ERC_Research
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🤔 that’s interesting. Restriction of HLA-DR expression on primitive #macrophages. A must read for all #ipsc lovers, as they know what I am talking about ;).
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The marathon team „MHHacrophages“ is ready for tomorrow having fun @Marathon_HAJ. Don’t miss the #macrophages on the track. Thanks @MHH_life see you all tomorrow @LachmannLab
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So excited to host #unistem23 event @MHH_life. We welcome 30 high school students to learn more about #stemcells and the beneficial use in future therapies. Stay tuned and join the UniStemDay around the #world #science #therapy
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Lachmann_Lab retweeted
Mitochondrial function in macrophages controls cardiac repair after myocardial infarction: buff.ly/3ka2YVH David Weissman & @ChristophMaack highlight the metabolic mechanism by which macrophages regulate cardiac repair following myocardial infarction; #Commentary
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