All views solely of Dr. Lamming and do not necessarily reflect views of my employers, funders, or societies. Retweet≠Endorsement. @LammingLab@fediscience.org
Joined April 2015
- Tweets 4,967
- Following 2,800
- Followers 6,169
- Likes 10,813
227 Photos and videos
Jun 7
Just rotating off study section myself, and I personally don’t see any difference - factor 1 is just the “old” Significance and Innovation and 2 is just Approach with any added weaknesses from environment and investigator.
The two factors are clearer and understandable. As a result, scores are much more consistent now, than in the past. It is a rare occurrence to see spread of preliminary overall scores of 3 points or more between three reviewers (eg 2, 2, and 5). (6/10)
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Jun 7
The primary change is that you can no longer speak to the expertise and former publications of the investigator and collaborators as a strength, and can only speak to weaknesses of the investigator and team. Which is a bit depressing even if necessary for unbiased review.
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May 13
Please enjoy my new review article "Bench to bedside: is rapamycin headed for the docTOR?"
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May 13
Rapamycin is one of the most promising gerotherapeutic agents in ongoing and upcoming clinical trials, showing robust extension of lifespan in multiple pre-clinical studies. Here we review the field discuss new results and discuss the many new and upcoming clinical trials!
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May 1
Terrific Department of Medicine Research, and congratulations to @iCCup_Spec and @baileyknopf for winning poster awards and @mariahcalubag for receiving the DOM Outstanding Graduate Student Award!
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Apr 17
Three amazing award winners from the Lamming Lab at the 7th Annual Midwest Aging Consortium Meeting! Congratulations to all the winners and all participants! @iCCup_Spec @baileyknopf @amirah_nie74532
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Lamming Lab retweeted
I’m excited to share new work out of the lab at @NYULangone led by @kenjifujihara! We took a first principles approach to evaluating #ferroptosis induction for cancer therapy via targeting the SLC7A11-glutathione-GPX4 axis. biorxiv.org/content/10.64898…
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Men lose nearly a year of life to a molecule that's supposed to boost their brains.
Tyrosine, a dopamine precursor taken by millions as a cognitive supplement.
@uk_biobank Mendelian randomization (MR), n=272,475: it causally shortens male lifespan by 0.91 years (p=0.01)
No significant effect in women.
Men naturally carry higher circulating tyrosine than women. The authors suggest this single amino acid difference may partly explain the male-female lifespan gap.
Nuance: MR captures lifelong endogenous exposure, not supplement effects. But the finding held across multiple MR methods and every sensitivity test.
If you're supplementing tyrosine daily, this paper deserves your attention.
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Mar 13
Please enjoy the latest publication from our lab "Restriction of Individual Branched-Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice"
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Mar 13
This work was made possible with the support of many collaborators in and outside the lab, including @garacreen Luigi Puglielli @WiscoSurgMetab @AttieLab and @CholsoonJ!
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Mar 13
With help from @AttieLab's lab a data visualization and analysis tool - we hope to make this tool more broadly available soon: connect.doit.wisc.edu/dlammi…
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Feb 22
Glad we were able to help this podcast happen!
Great work, Dudley and crew!
In video format, Dr. Yang-Yeh's presentation: youtube.com/watch?v=iGl5mz-l…
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Jan 29
Had a fantastic metabolism and aging retreat yesterday with the @JudithSimcox and @WiscoSurgMetab labs!
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22 Dec 2025
With the end of the year upon us, it's time for the 2025 @LammingLab year in review! Some of our accomplishments and successes are described in the thread below.
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22 Dec 2025
We celebrated the graduation of two of our graduate students, Dr. Reji Babygirija and Dr. Mariah Calubag @mariahcalubag! Reji is now a postdoc with @WiscoSurgMetab while Mariah is looking for a postdoc – snap her up soon!
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22 Dec 2025
Thanks to all of the @LammingLab members past and present for another terrific year, all our collaborators and colleagues for their help and friendship, and thanks as well to everyone who has participated in great conversations online and off about healthy aging, diet and mTOR!
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