Joined January 2014
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- Followers 1,293
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29 Photos and videos
Todd L. Lowary retweeted
🔬Publication - by Dr. Chun-Hung Lin @RoySocChem
This study presents a method to synthesize #tetrahydroquinoline #glycosides using exo-glycals and #arylamines. This method can also be applied to other molecules such as #anilines and glycosides. doi.org/10.1039/d6ob00392c
#biochem
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Todd L. Lowary retweeted
🔬Publication - by Dr. Hsiao-Ching Lin and Kai-Fa Huang @ACSPublications
The researchers found that #fungal #enzyme #AacA is a bifunctional albicanoyl monophosphate #synthase that catalyzes class II cyclization of farnesyl #pyrophosphate. doi.org/10.1021/jacs.6c04151
#biochemistry
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Todd L. Lowary retweeted
🔬Publication - by Dr. Peter Chi
This study shows that #DNA #helicase #HELQ works with BCDX2 to promote #replication fork reversal. doi.org/10.1093/nar/gkag332
#biochemistry #biochem #BRCA2 #FANCD2
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Todd L. Lowary retweeted
Publication - by Dr. Peter Chi and Hsin-Yung Yen @ACSPublications
#Helicase-like #transcription factor (HLTF) involves in #DNA replication fork reversal. This study reveals the ATP-induced dimerization of HLTF and its role in DNA unwinding activity. doi.org/10.1021/jacs.5c22675
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Todd L. Lowary retweeted
🔬Publication - by Dr. Chiaolong Hsiao @SciReports
A conserved radial distribution of #RNA A-#helices that characterizes the spatial structure of large #ribosomal subunits, providing a general ribosomal structure across evolutionary diversity. doi.org/10.1038/s41598-026-5…
#ribosome
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Todd L. Lowary retweeted
🔬Publication - by @khooAS @ElsevierConnect
#ST3GAL3 knockout significantly reduced #viral association, uptake, and transduction of #VSV, suggesting ST3GAL3-dependent #sialylation of LDLR N-#glycans is required for efficient viral entry. doi.org/10.1016/j.bbagen.202…
#glycosylation
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Todd L. Lowary retweeted
🔬Publication - by Dr. Hsiao-Ching Lin
Selective #serotonin reuptake inhibitors may induce #MDR in gut #microbiota and #antidepressant #tachyphylaxis, offering new insights for novel central nervous system-targeted #therapies. doi.org/10.1016/j.dmd.2026.1…
#biochemistry #biochem
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Todd L. Lowary retweeted
🔬Publication - by @asibc512 @ACSPublications
The mass photometry data demonstrated the diverse binding #stoichiometry across #SARSCoV2 #Omicron #subvariants, indicating that #S_protein mutations modulate #ACE2 engagement beyond mere affinity. doi.org/10.1021/acs.jpcb.6c0…
#biochem
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Todd L. Lowary retweeted
🔬Publication - by Dr. Yuan-Chih Chang @npjAMR
Cationic #peptide TP2-5, a ow-dose #antibiotic #adjuvant, showed envelope perturbation characterized by inner-membrane hyperpolarization, thereby enhancing antibiotic susceptibility of MDR E. coli. doi.org/10.1038/s44259-026-0…
#biochem
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Todd L. Lowary retweeted
🔬Publication - by Dr. Steven Lin @NatureComms
The newly established #genome-wide #CRISPR screening platform identified key regulators of #NK #cell functions, suggesting potential engineering targets for more potent NK #cancer #immunotherapy. doi.org/10.1038/s41467-026-7…
#biochem
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Todd L. Lowary retweeted
🔬Publication - by Dr. Wei Yuan Yang and Guang-Chao Chen @CellPressNews
This study suggests that #lysosomes can sense the magnitude of #autophagy loads and quantitatively translate this signal into TFEB activation. doi.org/10.1016/j.celrep.202…
#biochemistry #biochem
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Todd L. Lowary retweeted
Apr 18
Graded activation of the CLEAR network through mTORC1 suppression on c... sciencedirect.com/science/ar…
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Todd L. Lowary retweeted
🔬Publication - by Dr. Meng-Ru Ho
By using #chimeric #Fab fragment cZ22-Fab, this study demonstrated the mechanism of #antibody-mediated Z-#DNA formation and stabilization, highlighting its potential for #autoimmune #disease treatment. doi.org/10.1093/nar/gkag160
#biochemistry
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Todd L. Lowary retweeted
2026 IBC summer #intern program applications are now open!
👉Application deadline: 2026/4/30
For more information, please visit: w3.ibc.sinica.edu.tw/SummerI…
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Todd L. Lowary retweeted
🔬Publication - by @Lowarylab @jbiolchem
#Kdo #transferase #KrkA from #Ecoli synthesizes K13 #capsule, and study of E. coli isolates suggests #polyphyletic origins for this capsular #serotype. doi.org/10.1016/j.jbc.2026.1…
#biochemistry #lipopolysaccharide
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Todd L. Lowary retweeted
🔬Publication - by Dr. MENG-CHIAO HO @ScienceMagazine
#Vaccinia #virus uses a multicomponent entry #fusion complex. Researchers found that A16, one component of the fusion core may regulate #lipid engagement, and F9 reinforces the prefusion architecture. doi.org/10.1126/sciadv.aec02…
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pubs.acs.org/doi/10.1021/jac…
We are happy to share our work published in JACS that we found ProteinMPNN-designed protein (ubiquitin-fold proteins in this study) tends to recruit more water to for a persistent mesostructured hydration shell with enhanced stability. @IBCSinica @acsJACS
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Todd L. Lowary retweeted
🔬Publication - by Dr. Shih-Hsiung Wu @Sciencedirect
This study demonstrates that O-acetyl group on TSP-digested #exopolysaccharide from #Acinetobacter ##baumannii interacts with Toll-like receptor 4 macrophage and activates #immune response. doi.org/10.1016/j.carbpol.20…
#phage
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Todd L. Lowary retweeted
🔬Publication - by Dr. Yusuke Nasu @RoySocChem
This newly developed #GINKO2-a #nanofibres enabled reversible #potassium detection in chemically stimulated #mammalian cells. doi.org/10.1039/d5cc05871f
#biochemistry #biochem #protease #protein
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Todd L. Lowary retweeted
🔬Publication - by Dr. Ching-Ching Yu @WileyGlobal
TERS platform resolves subtle structural differences in glycosidic linkages, allows semi-quantitative estimation of chain length, and tracks enzymatic #glycosylation reactions in real time. doi.org/10.1002/anie.2025200…
#biochemistry
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