Respirologist @UHN | Asthma, Airways diseases & Smoking | Global Health, Data Science, Advocacy & Policy | Son-Husband-Father | .ca .pk | Views my own

Joined December 2014
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Replying to @respandsleepjc
@respandsleepjc A number of explanations for them not meeting primary outcome of SGRQ change which is a pretty "low bar", but best for symptoms: weaker dose (even if BID) than what is available in Canada, >1/3 of those randomized excluded from analysis for notable reasons- #rsjc
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10% withdrawal rate, and issues that highlight study validity issues - ineligible after randomization?? wrong kits?? adherence issues - fine, an issue in many inhaler Rx trials but can be mitigated/tracked
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Unpopular opinion but I'll say it again. If we're advocating for the fire to be doused in hotspots across #Peel and #Toronto, then we should be screaming at the top of our lungs to help #Indians and all hotspot countries however we can with their pandemic responses as well.
💯 Overcoming this and future pandemics in an increasingly globalized world requires a desire & will to equitably distribute all effective measures – testing kits, PPE, treatments or vaccines – not just to those disproportionately affected within our borders, but beyond as well.
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That is, if we are honest about valuing all lives as equal to our own. We are the Rosedale of the world and the longer this pandemic goes on, the more variants we'll have to contend with. Politics and greed have gotten us nowhere. Humanity is sacred and history will judge us.
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M. Hashim Khan retweeted
#RamadanMubarak everyone! Check out this 🧵 on how we can all observe a blessed and #SafeRamadan this year! To see our Ramadan 2021 guidelines, town hall, posters and infographics, please visit cmcovidtf.com #Ramadan2021 #Ramadan2021 [1/14]
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M. Hashim Khan retweeted
#Ramadan2021 is around the corner! So we've prepared a series of guidelines on how to observe this Ramadan season safely! Follow this thread 🧵:
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M. Hashim Khan retweeted
Task forces like ours have been working at the grassroots for months now to address vaccine hesitancy, myths, concerns and questions that are on the minds of these high risk community members. Mosques and Muslim HCWs are ready to deliver culturally competent care if given a shot.
Canada🇨🇦 should use places of worship as #COVID19 #vaccination sites to build trust and get vaccines to those have suffered the most, by @ananya_tb thestar.com/opinion/contribu… via @torontostar #cdnhealth #onpoli
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💯 Overcoming this and future pandemics in an increasingly globalized world requires a desire & will to equitably distribute all effective measures – testing kits, PPE, treatments or vaccines – not just to those disproportionately affected within our borders, but beyond as well.
We are on the brink of a catastrophic moral failure. As @WHO stated, distributing COVID-19 vaccines equitably is vital to end this pandemic. None of us will be safe until we are all safe. #VaccinEquity @DrTedros @DrSamira_Asma @PeterASinger @mvankerkhove @GHS @gavi @equitylist
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Just telling people to get the #COVID19 #vaccine once it's their turn will not work given high hesitancy. We are actively engaging with communities to openly discuss concerns, answer q's and clarify misconceptions with a diverse set of expert perspectives and relatable voices.
The Canadian Muslim COVID-19 Task Force would like to invite you to a virtual town hall entitled "Health and Hope on the Horizon: Understanding the COVID-19 Vaccines" on Sunday January 3, 2021 from 7:00pm - 8:30p.m. (Eastern Standard Time). #vaccinetownhall
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Add to list of secondary causes of hypertension: policies and decisions that will inevitably result in more COVID-19 cases, more hospitalizations, increased health system strain, more burnout and mental health issues and most importantly, more lives lost. #lockdownontario
There is no livelihood if there is no life. An ounce of prevention is worth a pound of cure. Short-term pain for long-term gain. Take your pick - the message is the same. We should aspire and dare to believe in a bold #COVIDzero strategy, since hedging clearly hasn't @fordnation
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Stating the obvious here but apparently it needs to be said: You cannot reduce community transmission without having community engagement or representation. This is public health promotion 101.
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All those interviews, charts, tweets, infographics, editorials and briefings over the summer, warning us of second waves in pandemics (historically and in other countries w/ #COVID19 that reopened before us)... and yet here we are. Let's hope it's a small one. #COVID19ON 1/3
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@fordnation and @PublicHealthON need to work together in reevaluating priorities & examining what's driving this wave to take decisive action NOW (and not just hit 'pause'). This is the result of actions 2-4 wks ago and we should act based on predictions for 4 wks from now. 2/3
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Not to mention that we've yet to fully open schools or the US border and #FluSeason is around the corner. Tick tock. Yes this is all driven by human behaviour, but was likely fueled by lack of shared decision-making and a failure of risk communication, community edu & prep. 3/3
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That's now at least 4 Thursdays in a row, where the line outside the @UHN #COVID19 assessment centre winds around the front of the hospital, noticeably longer than other days. Are people getting tested so they can make decisions re socializing "safely" on the w/e @SharkawyMD?
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Re: baseline demographics, TB and HIV made the list despite such low numbers but missing key confounder data for BMI, which hopefully should be available from hospital records. #rsjc
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We obviously don't know optimal dex dose (and what factors to adjust based on), but 6mg dex daily for 7 days is a reasonable start based on this. More safety data would have been nice but short course should be ok. #rsjc
Re the 8% cross-over of pts in usual care who ended up getting dex eventually, if anything it would have biased results towards null effect (and true effect likely greater) in their ITT analysis - right @drstanbrook? #rsjc
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Also, re: comorbidities and risk of #COVID19, adjusting for them may have been interesting. Groups appear balanced btw dex vs. usual care, and when see breakdown by resp support (Nil vs O2 vs MV), see balance somewhat maintained. ?equal access to Rx despite comorbidities? #rsjc
Sex-differences catch my attention in Table 1: more balanced in pts w/o O2 (58% M vs. 42% F), but then see more imbalance in O2 (63% M vs 37% F) and invasive MV (73% M vs 27% F) groups - is this due to recruitment? confirmation of higher risk in M, or differential Rx? #rsjc
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