Nuclear Receptors signaling group led by Mercedes Ricote at @CNB_CSIC. Transcriptional and epigenetic regulation of immune and cardiovascular systems!

Joined October 2020
5 Photos and videos
MRicoteLab retweeted
The pro-inflammatory role of microglia is considered a key driver of Alzheimer's disease. Today @NeuroCellPress discovery of an epigenetic regulator of microglial mitochondria in the experimental model that may be amenable as a target for therapy or prevention cell.com/neuron/fulltext/S08…
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MRicoteLab retweeted
Do not miss this video by Laura Casablanca @CNB_CSIC, in which she explains the latest findings from our article published in @JExpMed. We have identified the transcrptional network that enables a #macrophage to acquire its #macrophage identity.
📽️ See a short video summary of the study by Laura Casablanca: youtu.be/X-vHMKEXR9g
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MRicoteLab retweeted
Oxytocin signaling in adipocytes is required for normal milk fat production dlvr.it/TStvc8
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MRicoteLab retweeted
Hepatocyte Circadian Clocks Control Cholesterol #Metabolism and Protect From #MASH @AGA_CMGH cmghjournal.org/article/S235…
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MRicoteLab retweeted
"Murió de tristeza más de un año después del deceso de Mattias Ripa, su marido y el amor de su vida" Vuela a su encuentro Marjane 😢
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🤔Are you an international researcher looking for opportunities at CNB-CSIC? 📢Introducing CNB Attract 🙌Follow our new LinkedIn page, CNB Attract, and stay connected! ℹ️🔗f.mtr.cool/fsbqkzfdfh
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MRicoteLab retweeted
📰 A new study led by researchers from the Spanish National Research Council (CSIC) at the National Centre for Biotechnology (CNB-CSIC) @CNB_CSIC reveals how alveolar #macrophages acquire their identity and specific functions within the lung. 👉 hubs.la/Q04k7pKS0
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MRicoteLab retweeted
Regulatory T cells sabotage anti-tumor γδ T cells by creating IL-2–deficient environments. From @RafaelBlancoDom, @BSilva_Santos, Sofia Mensurado and colleagues: hubs.la/Q04jLFgF0   📘 Part of JEM #Cancer Collection: hubs.la/Q04jLP2J0 #EACR2026
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Congratulations! Must read if you are a #macrophage fan! 🎉🎉🎉
Our paper is out in @JExpMed ! How does a #macrophage become an alveolar macrophage? Many thanks to collaborators @CNB_CSIC @CNIC_CARDIO @karolinskainst . Read more: rupress.org/jem/article/223/…
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MRicoteLab retweeted
cell.com/issue/S0896-6273(25… On the cover: In this issue of Neuron, Du et al. @DuSiling show that repeated microglial depletion enables peripheral monocytes from both the blood and skull bone marrow to infiltrate the brain and engraft as monocyte-derived macrophages with distinct identities. Inspired by a passage from the Zuo Zhuan (“The first beat of the drum rouses the soldiers’ spirits; the second weakens their resolve; by the third, they are exhausted”), the artwork depicts three rounds of microglial depletion gradually exhausting the endogenous microglial niche. The two advancing armies represent distinct peripheral sources of invading cells: one arriving from the blood, illustrated by the army bearing the red flag, and the other emerging from the skull bone marrow, portrayed as descending from the mountains. Artist credit: Ying Xu.
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MRicoteLab retweeted
Exercise benefits may begin before conception. In mice, parental physical activity before mating shaped offspring body composition, hypothalamic gene expression, and early-life metabolic programming—with effects influenced by parental age and potentially mediated through changes in breastmilk composition. #ExerciseScience #Epigenetics #MetabolicHealth @WuTsaiAlliance pmc.ncbi.nlm.nih.gov/article…
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MRicoteLab retweeted
The many pathways driving liver inflammation in MASH dlvr.it/TSs7nN
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MRicoteLab retweeted
Our paper is out in @JExpMed ! How does a #macrophage become an alveolar macrophage? Many thanks to collaborators @CNB_CSIC @CNIC_CARDIO @karolinskainst . Read more: rupress.org/jem/article/223/…
Un equipo liderado por @MRicoteLab identifica las señales que promueven la especialización de macrófagos pulmonares Sin ellas, los macrófagos no completan su maduración y se compromete la salud pulmonar Más: f.mtr.cool/neofvhybvj  @JExpMed: f.mtr.cool/bespmvjyxl @nurcamein
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Un equipo liderado por @MRicoteLab identifica las señales que promueven la especialización de macrófagos pulmonares Sin ellas, los macrófagos no completan su maduración y se compromete la salud pulmonar Más: f.mtr.cool/neofvhybvj  @JExpMed: f.mtr.cool/bespmvjyxl @nurcamein
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