Joined March 2013
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Pinned Tweet
Replying to @MathiThiru95
Happy to be able to show some love to 🐟 gills, which I've really enjoyed learning about over the past two years. Excited to share the final publication soon! 🤞
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Really appreciated this opportunity from @the_Node to write about the amazing journey I got to be on for 6 years and the people I met on the way. Every day I feel fortunate to live in and work for a society that chooses to be curious. I hope it continues to do so. ✨
7 Mar 2025
Fish, Frogs, Friends, Lend me your Ears. 🐟🐸🐁🦎 Read this 'Behind the paper' story from @MathiThiru95 about her PhD work with @CrumpLab: thenode.biologists.com/fish-… #DevBio #EvoDevo
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Mathi Thiruppathy retweeted
Here is the 2025 embryo alphabet from alligator to zebrafish. Developmental biology is stunning & leads to important discoveries for human medicine. @SocDevBio @NIH @NSF
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22 Jan 2025
Nice article in Scientific American about our work on outer ear evolution and a complimentary study from the lab of Maksim Plikus on role of unique lipids in mammalian ear cartilage. @MathiThiru95 @USCStemCell @KECKSchool_USC scientificamerican.com/artic…
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Mathi Thiruppathy retweeted
Sox10 is required for systemic initiation of bone mineralization Read this Research Article by Stefani Gjorcheska, Lindsey Barske and colleagues @CincyResearch: journals.biologists.com/dev/…
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Mathi Thiruppathy retweeted
Excited to share our new publication, “Bidirectional histone monoaminylation dynamics regulate neural rhythmicity;” a massive collaboration across 5 labs (@Yael_David__ @MuirLab @SimoneSidoli and Haitao Li) See 🧵 below for the highlights nature.com/articles/s41586-0…
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10 Jan 2025
You can view the PDF of our gills to outer ears paper here: rdcu.be/d5Ml5 Also the link to the article on Nature is now working again: nature.com/articles/s41586-0…

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Mathi Thiruppathy retweeted
Welcome to embryo alphabet. Each day I will post an unannotated embryo image. Today E is for elephant. Repost tweet w/an image of a different species embryo & add a quote including name that begins with same letter of the day. @SocDevBio
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Excited to share this story from my PhD revealing the surprising legacy of our gill-bearing ancestry in the form of our cartilaginous outer ears, summarized in this series of Tweets.
9 Jan 2025
The outer ear is a mammalian innovation but where did it come from? In our study in @Nature, @MathiThiru95 and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. nature.com/articles/s41586-0… 1/n
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Thank you to all co-authors! @GillisLab @EvseenkoLab @YaWenChenMSSM @goodfrognosis and everyone not on Twitter/X. It's hard to emphasize how amazing it's been to work with people of such diverse expertise who still had an interest in various obscure aspects of this work.
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Thanks especially to @CrumpLab for providing the opportunity to do exciting, diverse experiments, as well as the necessary guidance and confidence!
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Mathi Thiruppathy retweeted
An @USCStemCell study published in @PNASnews has identified gene regulators that enable fish and lizards to naturally regenerate their hearing. The findings could guide future efforts to regenerate hearing for patients. @CrumpLab @KeckSchool_USC stemcell.keck.usc.edu/study-…
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Mathi Thiruppathy retweeted
🎉 We're excited to share our new research in @Nature! We reveal that crocodile head scales self-organize through compressive folding of the skin - a mechanical twist on their development & evolution! Please read & share 🐊🔬 @genevunige @UNIGEnews nature.com/articles/s41586-0…
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Mathi Thiruppathy retweeted
Embryology: Concepts and Techniques in Modern Developmental Biology 🧫 🧬 🔬 🦠 June 1 – July 15, 2025 Deadline: January 22, 2025 go.mbl.edu/embryology
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Mathi Thiruppathy retweeted
Do you love evo-devo and want to do a PhD on millipede trachea homology in beautiful Vancouver 🇨🇦? Come join my lab! form.jotform.com/24253453786… Please re-tweet :)
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4 Sep 2024
Our paper ‘Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis’ is now on biorxiv! We introduce weMERFISH, a platform for profiling gene expression in entire embryos at subcellular resolution. Here is🧵biorxiv.org/content/10.1101/… (1/12)
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Excited to start my postdoc in @kamberovlab at UPenn studying the development and evolution of eccrine sweat glands and human thermoregulation. Thanks to all my new lab mates for the warm welcome. 😃
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Mathi Thiruppathy retweeted
Pathway to Independence – an interview with Marcella Birtele @MarcellaBirtele, one of our PI Fellows, talks about how the research questions she hopes to address with her own lab will bridge her previous neurodegeneration and neural development studies: journals.biologists.com/dev/…
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Mathi Thiruppathy retweeted
Vasculature of adult zebrafish gills. Credit to Dr. Madina Wane. #ZebrafishZunday
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22 Aug 2024
What if you could deliver molecular tools directly into oocytes without microinjection? In our new paper, online today @Dev_journal (doi.org/10.1242/dev.202857), we introduce VitelloTag, a new cargo delivery tool to enable injection-free genome editing. 👇Read on for a short 🧵
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