Hematologist | @Sunnybrook | Associate Professor | @uoftmedicine | #lymphoma/Value/Health Outcomes | @ICESOntario | heme calc - qxmd.com

Joined May 2017
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Where are we after 20 years of R-CHOP in DLBCL? Update from #ASH21 with the POLARIX trial demonstrating a PFS benefit with pola-R-CHP vs R-CHOP (HR 0.73; p<0.02) but no difference in OS. #lymsm
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Matthew Cheung retweeted
17 Apr 2023
Congrats @CPSkorupski ⭐️ on this excellent 5 things to about about Preop anemia in @CMAJ! Such a great team to work with @MattCheungMD! 🙌 @LMP_UofT @UofT_DoM @Sunnybrook cmaj.ca/content/195/15/E551
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Matthew Cheung retweeted
Congratulations team on this important contribution to our understanding of COVID in pts with cancer. Led by rising star @igong26 . Bottom line: COVID outcomes worse in hem cancer and any on chemo. Booster shots help. @MattCheungMD @abivije @NicoleKuderer
29 Dec 2022
Vaccinated cancer pts had higher risk of breakthrough COVID-19 infection & poor outcomes incl. hospitalization & death, compared to controls without cancer, especially for those w/hematologic cancer or on active chemo. Third vaccine dose reduced this risk. ja.ma/3GqObhN
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Matthew Cheung retweeted
29 Dec 2022
Vaccinated cancer pts had higher risk of breakthrough COVID-19 infection & poor outcomes incl. hospitalization & death, compared to controls without cancer, especially for those w/hematologic cancer or on active chemo. Third vaccine dose reduced this risk. ja.ma/3GqObhN

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Matthew Cheung retweeted
17 Oct 2022
Carence en vitamine B12 : Les patients peuvent parfois présenter des symptômes neuropsychiatriques; examiner l’alimentation et la médication est important — cmaj.ca/lookup/doi/10.1503/c… @WKSilverstein @dryulialin @MattCheungMD

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Replying to @SinaiHealth
@SinaiHealth/@UHN Geriatrician, Dr. Shabbir Alibhai as well as @abivije @ancaprica @mattcheungmd et al. released a new study which explores #frailty in patients with newly diagnosed Diffuse Large B-Cell #Lymphoma receiving curative-intent therapy. To read: bit.ly/3NtG9Fh
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Matthew Cheung retweeted
22 Jun 2022
Vitamin B12 is necessary for normal bone marrow and central nervous system function. B12 deficiency can cause fatigue and pallor. Here are 5 things to know: cmaj.ca/lookup/doi/10.1503/c… @WKSilverstein @dryulialin @MattCheungMD
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Matthew Cheung retweeted
Vitamin B12 deficiency is common and presents diversely. This article in @CMAJ describes diagnostic criteria for vitamin B12 deficiency, common etiologies of vitamin B12 deficiency, and evidence-based strategies to treat vitamin B12 deficiency. cmaj.ca/content/194/24/E843
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Matthew Cheung retweeted
𝐉𝐮𝐬𝐭 𝐏𝐮𝐛𝐥𝐢𝐬𝐡𝐞𝐝: #Frailty in Patients With Newly Diagnosed Diffuse Large B-Cell #Lymphoma Receiving Curative-Intent Therapy: A Population-Based Study: buff.ly/39z7Z4Y @abivije @ancaprica @mattcheungmd @pmcancercentre #DLBCL #lymsm
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As we’re about to get access to Paxlovid….remember it’s co-administered with ritonavir for PI-boosting. With heme malignancy drugs, be aware of its CYP3A4 inhibition and use cautiously with venetoclax, ibrutinib, TKIs, anticoagulants, etc. #lymsm
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Matthew Cheung retweeted
News today of shortages of life-saving Covid drugs & HC approval of paxlovid (which will initially be in v short supply too). As a methodologist & a clinician, I wonder… how do you follow evidence-based guidance on drugs when you don’t have any drugs? 🧵 thestar.com/news/gta/2022/01…
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Matthew Cheung retweeted
As of today, It is illegal to intimidate doctors It is illegal to intimidate nurses It is illegal to intimidate patients, It is illegal to obstruct them from providing care or receiving it. This law was passed unanimously in the House of Commons, and it comes into force today.
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Always learn so much from Alison Moskowitz - editorial on precision approach to T cell lymphomas ascopubs.org/doi/full/10.120… #lymsm
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Congrats to @igong26 @abivije @LisaHicksMD for this extensive summary of COVID vaccine seroresponses and relative benefit (compared to control) in persons with heme malignancies. #lymsm onlinelibrary.wiley.com/doi/…
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Matthew Cheung retweeted
Really important data suggesting we should be COVID vaccinating patient prior to anti-CD20 based therapies.
13 Jan 2022
CD20-Targeted Therapy Ablates De Novo Antibody Response to Vaccination but Spares Pre-Established Immunity bloodcancerdiscov.aacrjourna…
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Matthew Cheung retweeted
10 Jan 2022
Happy to share our study aggregating COVID19 vaccine response in heme cancer. Thank you @abivije @MattCheungMD @LisaHicksMD and Stephen Betschel! Bottom line: lymphoid cancers, esp recent anti-CD20 Tx dramatically lower response onlinelibrary.wiley.com/doi/…

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CAR-T in 2L DLBCL - differences in study designs/populations likely explain different outcomes. Thanks to @mana1981 for help with the slide #lymsm #ASH21
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Matthew Cheung retweeted
24 Dec 2021
Thank you to all the health care workers — who won’t have much of a Christmas this year. Bless you all. 🎄
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