Thrilled to start 1/2026 as Chief of CV Medicine and Co-Director of the CV Institute @IUMedSchool / @IU_Health! Grateful for lifelong friends, colleagues, trainees @ NUFSM & continuing collabs. Excited for what's to come at IUSM/IUH! @IUSMDeptMed @saraj_pereira @IUCVInstitute

In UKB and MESA, IL-6 showed a stronger association with ASCVD than LDL-C, Lp(a), or hsCRP after mutual adjustment. This does not diminish the causality of LDL and Lp(a) but reinforces inflammation biology as a major driver of ASCVD risk. @ASPCardio @nationallipid @society_eas

Published today, the first-ever clinical practice guideline on cardiovascular-kidney-metabolic (CKM) syndrome from the American Heart Association and @ACCinTouch. The focus of this clinical practice guideline is to create a living, working document that provides current knowledge in the field of CKM syndrome aimed at all practicing cardiologists, endocrinologists, nephrologists, and primary care and specialty clinicians who manage these patients. ✍🏼 @ChiadiNdumele @HeartDocSadiya @kardiologykazi @noshreza @virani_md @biykemb @NutritionHF @mandeepbajaj65 @KatherineTuttl8 @RangaswJ @lisaVWMD @KBreathettMD @EmoryFamMed @ShoaClarke @mad_sters @jmortonmd @sripalbangalore @AnumSaeedMD

The Prognostic Value of Serum Interleukin-6 Concentrations for 9 Cardiovascular and Mortality Outcomes: The Cross Cohort Collaboration (CCC) | JACC jacc.org/doi/10.1016/j.jacc.… Very interesting analysis - two observations appear critical to me: 1) the CKD status matters - IL-6 more predictive in CKD (panel A); 2) if the IL-6 levels are high, the CRP levels don't seem to matter much (panel C).

Congratulations to Dr. Sam Weinberg on being named a Hartwell Foundation Investigator! His research on mitochondrial dysfunction and immune disease has the potential to advance treatments for children. We're proud to celebrate this recognition! thehartwellfoundation.com/20…

Lifestyle intervention-induced visceral adipose tissue (VAT) loss may persist despite weight regain and confer lasting cardiometabolic benefits: VAT loss, not weight loss, may be the key target for durable cardiometabolic health. ahajrnls.org/4vOOTwn

Our international group is absolutely ecstatic and SO grateful to receive this award from @FondationLeducq Stay tuned for some amazing science @ChiaraGiannare1 @ryden_mikael @edwardfisher20 fondationleducq.org/network/…

Review @SciImmunology The transcriptional and epigenetic regulation of macrophage differentiation, specialization, and activation in health and disease science.org/doi/10.1126/scii…

👏🏼 kudos to recently minted MDs @NagasakaReina @HAvgousti for leading this pilot effort borne out of a simple clinical question - how might PCI be affecting acute neutrophil responses. Great multidisciplinary collaboration! @SumaginLab @thorplab @jessquagginsmi1 @SchimmelHeart

✨ Thrilled to share our new publication in Nature. We define an “inflammatory memory” HSC state (HSC‑iM), linking lifelong inflammatory exposure to aging and disease. 📄 Article: nature.com/articles/s41586-0… Grateful to an incredible team and global collaborators 💚💙

Great to have you @shivkumarmd - enjoyed the conversations on past, present, and future!

Special day here at @IUCVInstitute @IUMedSchool @IUIntMed ! ✅Grateful to host the inspiring @shivkumarmd as Zipes visiting professor ✅Honoring John Miller and Anjan Sinha as the inaugural Zipes and Feigenbaum Distinguished Physician-Educators, with namesakes in attendance!

Congratulations to Andrew Gonzalez, MD, JD, MPH, FACS, on receiving national recognition for his National Institutes of Health-funded research focused on developing an intelligent clinical decision support system for peripheral arterial disease. His proposal was recognized as an outstanding submission and will support continued research and innovation in vascular care. 🔬🩺 Image description: graphic congratulating Andrew Gonzalez, MD, JD, MPH, FACS, on receiving the 2026 SVS Foundation/American College of Surgeons Mentored Patient-Oriented Research Career Development Award, featuring his headshot and IU School of Medicine Department of Surgery branding. IU Surgery | IU Surgery Research | IU Vascular Surgery |

#JustPublished: Lp(a), Evolocumab & First Major Coronary Event ahajrnls.org/4uqrRve

🚨What if we could reliably program macrophage polarization state?🚨 biorxiv.org/content/10.64898… Macrophages are highly plastic immune cells that perform critical functions by polarizing into distinct cellular states. The polarization state of macrophages can substantially influences the progression of cancers, infections, and autoimmunity. (1/11)

Great time in Ann Arbor for the our @AHAScience @AHAMeetings Inflammation SFRN! Outstanding engagement from all Centers - NU/IU/CSU, Pitt/PAMU, and UM/MGH/Oakland. Thanks @rosenzweig_a for hosting! @JSawallaGusehMD @chansteve73 @thorplab @IUCVInstitute @ParthaDuttaLab more

Happy to share our latest publication nature.com/articles/s41467-0… Led by outstanding @HereYuan @JingwenYang_, and wonderful collaboration with @CardioOncology Douglas Johnson, @DrYanyanLou! @IUIndianapolis @IUCancerCenter @HealthIusm60944

Great to have @chansteve73 @PittVMI in Indy! Fun catching up and talking all things inflammation as we work on @AHAScience SFRN collaborations and beyond. @IUCVInstitute @IUMedSchool @IUIntMed

Anti-inflammatory therapy targeting interleukin 6 receptor attenuate platelet activation in patients with myocardial infarction @KasparBroch @TuvaBDahl @BenteHalvo84025 @Halvorsen Lab_RIIM ahajrnls.org/4d4Lba9

Welcome to IU Surgery, Marc Gerdisch, MD, FACS, FACC, FHRS. 👏 Gerdisch joined our Division of Cardiothoracic Surgery on April 1, bringing nearly 30 years of experience and a global reputation in complex cardiac care. We’re excited to welcome his leadership and expertise in research, surgical training and quality care.  #IUCardiothoracicSurgery #IUSurgeryFaculty #IUSchoolofMedicine