The Lab of Daniel S. McGehee in the department of anesthesia and critical care at the University of Chicago. We study nicotine addiction, pain and parkinson's.

Joined September 2023
Photos and videos
The McGehee Lab retweeted
E163: How do octopuses coordinate their arms? [SJK Audio Edition] youtu.be/TaEPrsglDko?si=Ct7D… via @YouTube Check out the audio version of our newest article and learn how octopus arms have segmented neurons that allow them to make big and tiny movements at the same time!
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The McGehee Lab retweeted
Next week (Thursday, January 16th), we welcome Dr. Julia Cox, from Northwestern University, for the Department of Neurobiology Faculty Candidate Seminar. Join us! 📍KCBD 1103 at 10:00 am "Neural circuit mechanisms of value-based decision making"
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The McGehee Lab retweeted
Next week our Neuroscience Seminar Series features Dr. Karunesh Ganguly, MD PhD from the University of California San Francisco. Join us! 🗓️Tuesday, January 21st, 11:00 am | KCBD 1103 “Ensemble reactivations drive fast sequence learning”
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The McGehee Lab retweeted
Professors Christopher M. Gomez, MD, Richard Kraig, MD, PhD, James A. Mastrianni, MD, PhD, and Anthony T. Reder, MD, from the Department of Neurology, are on the list. Congratulations! 👏 uchicagomedicine.org/Forefro…
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The McGehee Lab retweeted
We will host our monthly Postdoctoral Research Series next week! Please join us to learn more about the work of Ting-Feng Lin, PhD from the Hansel Lab! 🗓️Wednesday, January 22nd, 12:00 pm 📍SBRI J461
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Congratulations @RagsdaleLab on an incredible finding and beautiful paper! rdcu.be/d6Ep0

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The McGehee Lab retweeted
one ion channel subunit, many faces. our preprint shows that multiple K conductances in 🐭vestibular hair cells require Kv1.8/Kcna10 --> Kv1.8-null hair cells generate larger and slower voltage⚡️ responses, which may impair fast detection of head motions biorxiv.org/content/10.1101/…
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The McGehee Lab retweeted
during this project, I loved getting to know "gK,L" --> gK,L is the low-voltage-activated K conductance that passes heaps of K from type I hair cells into the calyx cleft --> read more about non-quantal transmission here: doi.org/10.1073/pnas.2207466…
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The McGehee Lab retweeted
How does the octopus nervous system control its 8 wiggly uber-flexible arms and integrate information from all those suckers? Possibly, by modularity, suckerotopy, and cooperation between segments of the axial nerve cord ⬇️ nature.com/articles/s41467-0…
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The McGehee Lab retweeted
Thrilled to begin my tenure as @SSIBsociety President. Congrats to @Kanoski_Lab on his incredible stewardship of this amazing society. DM or email to learn more about the society and #SSIB2025 and hope to see you in Oxford, UK
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The McGehee Lab retweeted
I also want to encourage academia-bound underrepresented neuroscientists in their PhD stage to apply for this awesome opportunity! I have earned 2 years of funding for the rest of my PhD up to 4 years of funding for my Postdoc! Happy to help any applicants seeking advice :)
Honored to finally announce the best news I’ve gotten in my PhD so far- I have been awarded the NINDS F99/K00 D-SPAN!!!! My first fellowship(!) & first grant of many as I work towards starting my own lab investigating neural mechanisms of visceral pain. (Thread!!)
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The McGehee Lab retweeted
Nice write-ups about @TruongLy18's new paper, with comments from Nick Betley, Haijiang Cai, @LuckmanLab, @LoraHeisler, and @_Chen_Ran_. Science: shorturl.at/oNX08 Nature: shorturl.at/beszR UCSF: shorturl.at/pqMPW @UCSF @HHMINEWS

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The McGehee Lab retweeted
Our napping, memory, and Down syndrome paper was just published in PNAS. Napping REM does not support memory consolidation in Down syndrome children. Great work Spanò, Edgin and Company. This is also my first human study! There is life beyond the rodent. pnas.org/content/early/2018/…
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The McGehee Lab retweeted
Check out this beautiful video from one of our #OpenScope projects! All panels were recorded simultaneously. The top plane are dendrites in the brain's top layer. The bottom row shows activity in a deeper layer of the brain – layer 5. More on OpenScope: alleninstitute.org/division/…
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The McGehee Lab retweeted
New print Myelination out today and available via link below. This pretty pretty process of glia wrapping their membranes around axons not only makes our brains faster and more efficient. gregadunn.com/product/myelin… #myelin #glia #neuron #neuroscience #brain
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The McGehee Lab retweeted
After five years of hard work, I'm SO excited to share my first-ever first-author paper in the @Sheffield_Lab! We went into this project with a simple question: how do we regulate contextual fear memories? 1/17
Direct Thalamic Inputs to Hippocampal CA1 Transmit a Signal That Suppresses Ongoing Contextual Fear Memory Retrieval biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Study by Shivang Sullere, PhD, a previous CON graduate student in the @McGeheeLab, is the topic of this week's NIH Director's blog! Check it out: directorsblog.nih.gov/2023/1…

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The McGehee Lab retweeted
"Alternative pain control circuits in the brain produce relief similar to opioids without the downsides" Study by Shivang Sullere, PhD, a previous graduate student in the @McGeheeLab, suggests a promising path to developing non-opioid painkillers! neuroscience.uchicago.edu/al…
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The McGehee Lab retweeted
“A cholinergic circuit that relieves pain despite opioid tolerance” by Daniel McGehee et al. Neuron doi.org/10.1016/j.neuron.202… 2/2

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The McGehee Lab retweeted
A new study reveals a non-opioid pain relief pathway using acetylcholine! Targeting the ⍺7 receptor offers analgesic effects comparable to opioids, minus the addiction risks. A game-changer in pain management. neurosciencenews.com/acetylc… #neuroscience 1/2
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