A popular FDA-approved drug to treat hypertension, hydralazine works, at least in part, by modulating RGS proteins! Honored to be a part of a collaborative team led by @MegaMatthewsLab!
biorxiv.org/content/10.1101/…
1/14 Our latest study just out on BioRxiv [biorxiv.org/content/10.1101/…] has unusual personal significance for me. It connects two apparently unrelated diseases – (pre)eclampsia and glioblastoma – that have both impacted my family.
14/14 We are extremely excited to leverage these new findings for (pre)eclampsia and glioblastoma drug development, and we are actively seeking investors and partners for our company, Zenagem, LLC, to move forward.
I’m speaking at ‘Emergence of irreversible modulation in drug discovery’ on 16-17 October 2024! Join us in Cambridge where we will bring together established leaders and emerging investigators exploring irreversible covalent modulators. Register now: ow.ly/iVIl50QwiKs”
Calling people "toxic" is rarely helpful. It focuses on their impact instead of their actions.
Toxicity comes in 5 flavors: disrespectful, dishonest, cutthroat, exclusionary, and abusive.
A good warning pinpoints patterns of behavior that are problematic and persistent.
sloanreview.mit.edu/article/…wsj.com/health/wellness/toxi…