Joined July 2017
18 Photos and videos
Pinned Tweet
18 Jul 2022
Two years ago, we reported for the first time on #cardioids. Now, our team, led by two fantastic Ph.D. students, Alison and Clara, developed multi-chamber cardioids representing all the major regions of the human embryonic heart (atria, LV, RV, OFT, AVC) biorxiv.org/content/10.1101/…
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Force regulation of myogenesis by Tono, a BTB-Zn finger transcriptional regulator, which forms droplets after acute high pressure application. It responds in 1 minute :) - in yellow in the nuclei sciencedirect.com/science/ar… Congrats to Xu Zhang and @JrmAvellaneda #Drosophila #muscle
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Beyond thrilled to present our first (!) work @TheCrick! A tour de force by @tobyandrews et al combining imaging, solid morphometrics, theory, perturbations to show how a developing heart grows and scales up its morphological complexity to keep beating... biorxiv.org/content/10.1101/…
Pumped to share our latest and first (!) work from @_Priya_R lab @TheCrick! Using the powers of #zebrafish, we uncover how multiscale mechanochemical coupling drives morphological and functional maturation of the developing heart 🫀 Stay tuned for the🧵 biorxiv.org/content/10.1101/…
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Very excited to see our new paper online @Nature, where @justuskleifeld @Patricia_Rothe_ and myself decipher the molecular choreography for how disassembly of the spliceosome begins. This was a great collaboration between the @plaschka_lab and @LCochella lab @IMPvienna.
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'The Mechanics of building functional organs - our take on this fundamental problem. We discuss general design rules building complex 3D geometries, advocate for a holistic understanding of morphogenesis by embracing the complexity of embryonic development.cshperspectives.cshlp.org/co…

How do embryos build organs with the right shape, size and function to keep our bodies ticking?🫀🫁👀 @_Priya_R and I give our take here, in a rollercoaster ride from local cell behaviors to organ-scale physiology and back cshperspectives.cshlp.org/co…
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Congratulations to Clara Schmidt, @MendjanLab, who successfully defended her PhD thesis titled “Multi-Chamber Cardioids Unravel Human Heart Development and Cardiac Defects!”
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Meet EcoBot the professional weeder. The Machine Learning, Solar powered apparatus that can run for the entire day pulling weeds. Replaces expensive in every possible way, herbicides.
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Elly Tanaka will be IMBA’s new Scientific Director, heading the institute from April 2024 onwards. Elly Tanaka is a renowned researcher, who studies the regeneration of complex body parts. Welcome, Elly!
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New manuscript alert! Writing in @Nature, the Burga Lab (@arburga) describe a genomic silencing mechanism which represses a selfish genetic element in the eggs of the nematode C.tropicalis only when it is paternally inherited. Their findings reveal the potential evolutionary origin of genomic imprinting. oeaw.ac.at/imba/research-hig…
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What a beautiful sight - children with Microscopes, curiosity in their eyes learning the wonders of Developmental Biology! Terrific outreach event organised by @InSDB_79 and fantastic students at @NCBS_Bangalore. Great start to InSDB 2024!
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Our new data-driven mathematical model of sarcomere assembly is now out. All the math was done by our fantastic collaborators in Dresden @friedrich_group @PoLDresden @IBDMmarseille @ClaraMSidor @BDehapiot journals.aps.org/prxlife/pdf…
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5 Jan 2024
What graduate degree should you go for? The MBA, the MD, the JD, or the PhD? The PhD is unique - it has to be said - for teaching both critical reasoning and the creative process of discovery; skills that prepare you for anything you’d then want to do.
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One decade after starting this journey, our collaborative paper with @Gibson_lab is finally out: rdcu.be/dtupS. It reports chromosome assemblies of the related sea anemones @Nematostella and Scolanthus callimorphus. Will be an important resource for the community.
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Is there a better way to make PGCs in culture than with disorganised EBs and signalling cocktails? In our latest pub @Dev_journal we show that mouse 'gastruloids' make beautiful PGCs... 😍 [as also seen by others] (1/6) doi.org/10.1242/dev.201790
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Why do we get certain diseases whereas others do not exist? This new book builds a foundation for systems medicine. Starting from basic laws, it derives why hormone, immune and aging circuits are built the way the are, culminating in a periodic table of diseases.
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Cannot recommend this enough!
Our laboratory for blastoid development and implantation is seeking a postdoctoral fellow to work with us on human embryogenesis. Our core-funded laboratory is located at the IMBA Institute of the Austrian Academy of Sciences in amazing Vienna. Please reTweet and get in touch!
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An interactive resource of molecular signalling in the developing human haematopoietic stem cell niche Read this Human Development Article by Edie Crosse @edie_crosse, Alexander Medvinsky @EdinUni_CRM and colleagues: journals.biologists.com/dev/…
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