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Metaboholics Lab @MetaboholicsLab

Official @almut_schulze Lab @DKFZ Heidelberg

Joined April 2021
  • Tweets 14
  • Following 53
  • Followers 143
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Spatial stable isotope tracing into fatty acids now in Nature metabolism. The result of a fantastic collaboration with @thalexandrov @space___out Mans Ekelof @Michi_MSH @gjpattij
Nature Metabolism
@NatMetabolism
9 Sep 2024
Online now! Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer dlvr.it/TD1T1N
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We are pleased to have contributed to this excellent series on #cancer #metabolism: Historical Landmarks, New Concepts, and Opportunities @CSHLPress @_alinamw Kamal Al-Shami @adrianobcfilho @FelixCEV @almut_schulze perspectivesinmedicine.cshlp…

Felix C. E. Vogel@FelixCEV
16 Jul 2024
🚨New Book Chapter in @CSHLPress 🚨 perspectivesinmedicine.cshlp… We reviewed how oncogenic signaling regulates fatty acid, lipid, and cholesterol #Metabolism to drive #Cancer growth, stress response, metabolic plasticity and #ferroptosis @MetaboholicsLab @DKFZ @Ferroptosis2306
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Featuring insights from the top researchers in the field, this is a must-read for anyone interested in #Ferroptosis in Health and Disease. Special thanks to Carsten Berndt and @Conrad_Lab for putting together this special issue. #lipidmetabolism #cancermetabolism @DKFZ
Felix C. E. Vogel@FelixCEV
3 Jun 2024
🚨New Review Alert🚨 Dive into our comprehensive state-of-the-art review on #Ferroptosis in Health and Disease. Discover the mechanisms, methodologies, and therapeutic potentials from top experts in the field. Many thanks to Carsten Berndt & @Conrad_Lab sciencedirect.com/science/ar…
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Big congrats to Kamal 🥳 Well deserved! #AACR @DKFZ
Almut Schulze 🧬🔬@almut_schulze
7 Apr 2024
Congratulations to our PhD student Kamal Al-Shami for winning the AACR-Ludwig Institute for Cancer Research Scholar-in-Training Award at the #AACR Annual Meeting for his work on defining oncogene-specific vulnerabilities in liver cancer. Well done Kamal!
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Our latest review paper on metastasis formation in solid tumors: Changes in lipid metabolism play a crucial role in the pro-metastatic phenotype of solid tumors. @DKFZ #CancerResearch #cancermetabolism
Felix C. E. Vogel@FelixCEV
25 Jan 2024
I am excited to share our @NatureCancer review on the role of #lipid and #fattyacid #metabolism in #cancer progression and #metastasis! @MetaboholicsLab @adrianobcfilho @almut_schulze @DKFZ 🥳nature.com/articles/s43018-0…
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Felix C. E. Vogel@FelixCEV
4 Jan 2024
Very happy to share: Our collaborative study together with the Moshe Oren Lab @WeizmannScience reveals that loss of TP53 in breast cancer cells orchestrates a profound and tumor promoting reprogramming of adjacent adipose cells. @MetaboholicsLab @DKFZ pnas.org/doi/10.1073/pnas.23… 1/4

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Almut Schulze 🧬🔬@almut_schulze
23 Dec 2023
Extremely thrilled to announce the publication of our joint paper with Moshe Oren and his group @WeizmannScience on the role of p53 in immuno-metabolic cross talk between breast cancer cells and adipocytes. @MetaboholicsLab @DKFZ Online now at PNAS. pnas.org/doi/10.1073/pnas.23…

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José Pedro Friedmann Angeli@AngeliFriedmann
12 Jul 2023
Now online in @EmboMolMed, a joint effort between our group and @hi_stem_lab. Work spearheaded @HamedAlborzy #zhiyichen and #umutydiz Only possible due to the great support offered by @Ferroptosis2306 embopress.org/doi/full/10.15… Congrats to al co-aurhors!!!

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

EMBO Molecular Medicine - Ferroptosis has emerged as an attractive strategy in cancer therapy. Understanding the operational networks regulating ferroptosis may unravel vulnerabilities that could...

link.springer.com
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🚨We celebrate our latest paper from Carina Maier @DKFZ in close collaboration with Oliver Hartmann @DiefenbacherL @Uni_WUE published @cddpress 🥳Thanks to all the collaborators @MYCGyvers @MuenchLab @Marco_A_Calzado @MSNZ_wuerzburg @goetheuni @IMIBIC nature.com/articles/s41418-0…

USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer

Cell Death & Differentiation - USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer

nature.com
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We are delighted to announce our #Spotlight @trendscancer by @_alinamw, highlighting the groundbreaking research by @alteam_patricia @FendtLab on the crucial role of palmitate in the formation of the pre-metastatic niche in the lung @NatureCancer. cell.com/trends/cancer/fullt…

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HI-STEM - Cancer and Stem Cells in Heidelberg@hi_stem_lab
19 Oct 2022
Congratulations Hamed @HamedAlborzy🥳! Great that you had an exciting an successful time at the #CSHAsia meeting!
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Congratulations @FelixCEV for being awarded one of the four poster awards at the @CSHANews meeting on #Iron, #ROS & #Ferroptosis in Life, Death & Disease at #Awaji Japan 🥳 @Ferroptosis2306 @DKFZ #cancer #metastasis
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