Happy Transposon Day 2022! Today is the 120th birthday of Barbara McClintock, founder of the #transposon field and Nobel laureate. Please celebrate with us by using the hashtag #TransposonDay2022. How has Barbara McClintock or her work influenced you? mobilednajournal.biomedcentr…
Congrats to @kellogg_liz and co for the first lab pre-print and very happy to be on board! More Tn7-like transposon structure and mechanism to see, this time of the #CRISPR-Cas wielding RNA-guided variety.
The @kellogg_liz lab has posted its first pre-print! Here we continue our mechanistic studies of 'jumping genes' or transposases, in close collaboration with @JoePetersLab on CRISPR-associated transposases ( Type V-K CAST elements).
biorxiv.org/content/10.1101/…
Expanding our understanding of dual-pathway transposition (1 - plasmids; 2 - chromosomal attachment sites) with Tn7-like elements one family at a time. New preprint from bioinformatics wizard @PopoMicro on Tn7-CRISPR-Cas12k
Tn7-CRISPR-Cas12K transposons categorize guide RNAs for different types of integration targets. Previously shown for type I-F3 systems. Grad student @PopoMicro shows an analogous process evolved with Cas12K systems. 1/6 biorxiv.org/content/10.1101/…