Interesting groundbreaking stuff showing how cells adapt to stressful conditions. They deprioritize their professional roles and invest on survival. I wonder how this extends to human societies when people are stressed..
Under stress, hepatocytes increase genes that promote survival (e.g., anti-apoptosis, WNT), but decrease genes related to professional roles (e.g., metabolic enzymes, secreted proteins, lineage-determining transcription factors; see text for drug targets like FXR and THRB!) (4/n)