Studying genetic, environmental, and host factors in tumor progression of #PancreaticCancer and #LungCancer @YaleGenetics @YaleCancer @CancerYale @YaleMed
Joined February 2018
- Tweets 562
- Following 417
- Followers 1,337
- Likes 3,168
103 Photos and videos
Muzumdar Lab retweeted
Join us for TOMORROW for “From mouse to man: Genetically engineered mouse models reveal conserved mechanisms of metastasis in human cancer” with Cory Abate-Shen, Columbia University, Friday June 5 @ 9:00AM, at the Yale Cancer Biology Institute
@YaleCancer @YaleMed @YaleWestCampus
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Muzumdar Lab retweeted
Congratulations to @Nelson_LaMarche, assistant professor @yalepathology @CancerYale, who has received a Breaking Barriers in Cancer Research award from the V Foundation bit.ly/4uRUpya @TheVFoundation
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Muzumdar Lab retweeted
Thank you, Yale Medicine Magazine, for highlighting my lab and my amazing colleagues Professors Etienne Caron, Liza Konnikova, Smita Krishnaswamy, and Sai Zhang in this nice article introducing the diverse and fundamental biomedical research at @YaleMed.
m.yale.edu/djjk
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May 30
Congrats to MD/PhD student Dan McQuaid on defending his thesis! His work established islet CCK as a bona fide driver of #obesity-driven #PancreaticCancer, positioning it as a potential risk biomarker and prevention target. @YaleMDPhD @YaleCancer @CancerYale @YaleGenetics
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Muzumdar Lab retweeted
May 27
Dr. Luisa Escobar-Hoyos @Escobar_Lab explains the challenges within #pancreaticcancer treatment, how patient outcomes can be improved, new drugs offering hope for patients, and more in this Q&A.
news.yale.edu/2026/05/22/why…
@SmilowCancer @YaleRadOnc
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Muzumdar Lab retweeted
May 26
Pancreatic #cancer is among the deadliest cancers, with a five-year #survival rate of just 13%. In a @Yale Q&A, YSM's Luisa Escobar-Hoyos, PhD, explains what makes this "silent disease" so hard to detect – and so challenging to treat after #diagnosis: bit.ly/4nN3ZPT
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Muzumdar Lab retweeted
It's not how much fat you eat, it's what kind 🥑
@YaleMed Prof. Mandar Muzumdar @MuzumdarLab shows how monounsaturated fats protect pancreatic cancer cells from ferroptosis, while polyunsaturated fats increase their vulnerability.
See more here👇medicine.yale.edu/news-artic…
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Muzumdar Lab retweeted
May 15
Research from @Escobar_Lab team identified a metabolic vulnerability in an aggressive subtype of #pancreaticcancer. Targeting the #K17-driven pathway improved chemotherapy response and doubled survival in preclinical models.
aacrjournals.org/cancerres/a…
@SmilowCancer @CR_AACR
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Muzumdar Lab retweeted
Great job Gigi and all at the Muzumdar and Liu Labs! We love to see these collaborative papers among our amazing labs at #YCBI @Yanshen73854711 @MuzumdarLab @YaleWestCampus @YaleCancer @YaleMed
May 7
🎉 Excited to share our new paper led by @Xiangyu_GigiG in @CR_AACR! 🧬 We flip the script on the RAS/PI3K relationship: PI3K is more than a RAS effector, it is also its regulator! @YaleCancer @CancerYale @YaleMedicine @YaleGenetics @yalepathology
aacrjournals.org/cancerres/a…
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Muzumdar Lab retweeted
Join us for a MORNING seminar: “From mouse to man: Genetically engineered mouse models reveal conserved mechanisms of metastasis in human cancer” with Cory Abate-Shen, Columbia University, Friday June 5 @ 9:00AM, at YCBI #YCBI
@YaleCancer @YaleMed @YaleWestCampus
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Muzumdar Lab retweeted
New research from @MuzumdarLab identifies PI3K-driven wild-type RAS activation as a key mechanism of resistance to KRAS inhibition in #pancreaticcancer. Combining PI3K and KRAS inhibition may help enhance therapeutic response in PDAC.
aacrjournals.org/cancerres/a…
@SmilowCancer @CR_AACR
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May 7
🎉 Excited to share our new paper led by @Xiangyu_GigiG in @CR_AACR! 🧬 We flip the script on the RAS/PI3K relationship: PI3K is more than a RAS effector, it is also its regulator! @YaleCancer @CancerYale @YaleMedicine @YaleGenetics @yalepathology
aacrjournals.org/cancerres/a…
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May 7
🧩Mechanistically, PI3K activity promotes PIP3-dependent membrane recruitment of GAB1 to form an EGFR/SHP2/SOS1 signalosome, enabling wild-type RAS/MAPK signaling. What’s more? This leads to resistance to KRAS inhibition, providing a rationale for co-targeting PI3KI and KRAS. 🎯
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May 7
💡 This redefines the classic KRAS→PI3K hierarchy and reveals a bypass route that supports resistance to mutant KRAS–specific inhibitors. Special thanks to collaborators (@Yanshen73854711 @moitrayee_lab) and funders (@NIH @NSF @lustgartenfdn @AmericanCancer)!
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Muzumdar Lab retweeted
.@YaleCancer #GrandRounds, Dr. Prasanna Ananth asks, “What defines high-quality end-of-life care for children with #cancer?” and provides insight into both what and how we measure what is most important to families with children facing #advancedcancer. #childhoodcancer. Watch her full talk youtube.com/watch?v=4zPhlgKF…
@SmilowCancer @YalePediatrics
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Muzumdar Lab retweeted
In a new study, @YaleGenetics researchers report that when it comes to your risk of pancreatic #cancer, the types of #fat in your #diet matter more than the amount of fat consumed: medicine.yale.edu/news-artic…
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Muzumdar Lab retweeted
New findings from @MuzumdarLab @CancerYale suggest that, for pancreatic cancer, the type of fat you consume matters more than the amount. bit.ly/islessmore @CD_AACR
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Muzumdar Lab retweeted
Now online in @CD_AACR: Diet-induced Phospholipid Remodeling Dictates Ferroptosis Sensitivity and Tumorigenesis in the Pancreas - by @ChristianFRuiz @MuzumdarLab and colleagues @YaleGenetics @YaleCancer @CancerYale @YaleMed
Apr 30
Now online: Diet-induced phospholipid remodeling dictates ferroptosis sensitivity and tumorigenesis in the pancreas doi.org/10.1158/2159-8290.CD…
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Muzumdar Lab retweeted
Apr 29
New research from @MuzumdarLab shows it’s not how much fat you eat, but the type that may drive risk of #pancreaticcancer. Some fats were found to even suppress tumors.
medicine.yale.edu/news-artic…
@SmilowCancer @YaleGenetics @CD_AACR
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