Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research.
Joined November 2011
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Our JUNE issue is now live!โ๏ธ๐
It features #REVIEWs on:
- Balancing type I interferon signalling
- Interplay between steatotic liver disease and liver cancer
- KMT2C/KMT2D-COMPASS complex loss in cancer
- #ExpertRecommendation on ovarian cancer
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NEW content online! AACR 2026 dlvr.it/TT0r41
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Rare cancers remain underserved by precision oncology. In this #Comment, Gujral et al. propose that systematic, variant-level pharmacological mapping of approved kinase inhibitors can transform this gap.
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In this #ToolsoftheTrade article, Guangqing Lu describes the development and use of cytokine cellular locating platforms (CyCLoPs), a technology that enables visualization and tracking of cytokine signalling in vivo.
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NEW content online! PRISM enables accurate microbial discovery in cancer genomics dlvr.it/TSxYls
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#ResearchHIghlight ๐จ
Hu et al. show extracellular vesicles (#EVs) from activated T cells enhance antigen presentation in tumour cells and dendritic cells, promoting immune-mediated tumour clearance
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Nature Reviews Cancer retweeted
๐จHot off the press ๐Published a day after @ASCO #ASCO26 ๐Pleased to share our comment in @NatureRevCancer @NaturePortfolio
๐"Mutation-centric kinase drug repurposing for rare cancers"
๐Rare cancers remain underserved by precision oncology.
๐We propose that systematic, variant-level pharmacological mapping of approved kinase inhibitors can transform this gap into an opportunity for scalable drug repurposing
๐Pleasure to collaborate with Dr. T. Gujral et al at
@fredhutch @OncoAlert @PGrivasMDPhD @targetcancer @oncodaily @OpenMedicineHQ
nature.com/articles/s41568-0โฆ
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#JournalClub๐จ
Stephenson-Gussinye & Furlan-Magaril explore how 3D genome reorganization explains why only some variants drive gene expression changes in cancer
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In case you missed this #JournalClub๐จ
Terrazas&Peรณn discuss a recurrent CTNNB1 mutation generating public #neoantigens recognized by engineered #TCRTcells, enabling potent antitumour responses across models
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NEW content online! Detection of cytokine-responsive cells using CyCLoPs dlvr.it/TSq5WC
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NEW content online! Mutation-centric kinase drug repurposing for rare cancers dlvr.it/TSq5JJ
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#FreeAccess ๐จ
If you want to know more about #OvarianCancer, check out our #ExpertRecommendation on the progress in research and treatment of high-grade serous ovarian cancer. Completely free to access for 1 month from today!
@IUCancerCenter
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#JournalClub ๐จ
Dรญaz-Muรฑoz discusses how IFC-305 restores mitochondrial structure and bioenergetics while reducing tumour burden in a rat model
@UNAM_MX
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Nature Reviews Cancer retweeted
Dr. Lan Coffman and co-authors summarize the roles of #MSCs in promoting or inhibiting carcinogenesis.
They highlight emerging concepts including epigenetic reprogramming of MSCs to switch from a tumor suppressive to tumor-supportive phenotype.
๐ก go.nature.com/49opdO9
๐: @NatureRevCancer
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NEW content online! An adenosine derivative for the treatment of hepatocellular carcinoma dlvr.it/TSn746
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#Review ๐จ
Emerging evidence links loss of the Y chromosome to cancer risk, progression and outcomes, highlighting its potential as a biomarker for prognosis and precision therapy.
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NEW content online! Message in a vesicle: T cells boost tumour immunity dlvr.it/TSmRxQ
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NEW content online! Structural variants disrupt chromatin architecture dlvr.it/TSm92t
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Lan Coffman&Co discuss the context-dependent role of mesenchymal stromal/stem cells (#MSCs) in supporting and restraining cancer growth and highlight how MSC biology can be exploited for cancer treatment.
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