A take on the current state of biased signaling in psychedelic action and psychedelic drug discovery by John McCorvy and I: Biased Signaling in Psychedelic Action | Annual Reviews - go.shr.lc/4lx1pLf

Our latest work: As it turns out different positive allosteric modulators bind to different sites at the mu opioid receptor. Find out more in our @biorxivpreprint. biorxiv.org/content/10.1101/…

There are 4 narratives about Harris' defeat we keep being told: - The US became more conservative - Harris was too far left/woke - It happened despite Biden doing what the Left wanted - It was all racism/sexism Why they're all wrong, in detail: jacobin.com/2024/11/harris-e…

Via our parent company @GlobTetrahedron CEO @BryceTetraeder: theonion.com/heres-why-i-dec…

If you pick any technology or product that these people rely on or consume regularly, somewhere in that thing’s origin or production process will involve some research that got federal money that can be narrated out of shape like this.

Look at my labor party dawg we’re never getting healthcare

Thankfully it failed to pass. Here's a list of MAGA fascist Democrats: x.com/JordanUhl/status/18564…

Earlier this year I wrote about Germany's disturbing relationship with Jews for @thebafflermag. In light of the "Antisemitismus Resolution" passed last week, it seems I can now be labeled an antisemite by the country that murdered most of my family. thebaffler.com/latest/how-ge…

Stefanik proudly promoted the antisemitic “Great Replacement” conspiracy theory that has motivated mass murders. Yet the head of ADL is eager to embrace and legitimize her and other Trump lackeys, prioritizing the shielding of Israel from criticism over American Jewish safety.

The problem with liberalism is that it rests on a fundamental contradiction that cannot be resolved. It will always fail, it will always collapse, and this explains everything about our current moment. Liberals try to hold two commitments at once: on the one hand, they are firmly committed to capitalism; on the other, they express support for principles like human rights, democracy, equality, freedom of speech, environment and the rule of law.  This duality is the core of liberalism. But there's a problem. Capital accumulation requires cheapening labour and nature. This eventually comes into direct conflict with principles like rights and equality. And whenever this conflict appears, the liberal ruling class sides with capital, abandons their lofty principles, and throws workers and nature under the bus.  Every. Single. Time. This results in flagrant displays of hypocrisy. They run on nice-sounding platforms but end up either betraying their promises or actively working against their stated values. They'll slash public services, bail out banks, imprison journalists, beat up students, expand fracking, coup democratically elected leaders in the global South, bomb liberation movements, fund a genocide - they'll even trash international law itself - anything that's needed to maintain the conditions for capital accumulation. At most, they may try to negotiate mediocre compromises, a few social policies here and there - some abortion rights, a tiny increase in the minimum wage - but nothing that might pose any serious threat to capital accumulation. Thus the soul-crushing slowness of liberal incrementalism.  Ultimately they are unwilling to take any of the obvious steps that would actually resolve our urgent social and ecological crises. This is why nobody trusts liberal politicians.  This is why they come across as so fantastically insincere, and even sneering.  This is why they feel so spineless and *empty*. The center cannot hold.  Liberalism will always collapse, inevitably handing power to fascists, and this is not acceptable.  There is only one way to overcome this deadly impasse, and that is to mobilize a socialist alternative. A political movement that can unite the working-classes, overcome capitalism, deliver real economic democracy, and enable us to achieve rapid progress toward social and ecological goals.

I don’t want to hear from anyone who hasn’t made a grocery budget in the last decade, because if you are calling what Biden did “economic populism” the likelihood you haven’t ever spoken to a poor person that wasn’t delivering your chipotle is too high to take you seriously.

Biden and Harris ran for president as candidates of the system, right down to campaigning with Dick Cheney’s daughter, Liz. As Democrats reckon with the future of their party, foreign policy must be part of the reckoning. My thoughts in @guardian: theguardian.com/commentisfre…

Yeah man, we should torpedo what little trust there is left in science as an institution by rejecting the Belmont Report

The lie is still up at NYT, with a vague video caption overpowered by the headline: nytimes.com/2024/11/08/world…

Wait I was told democrats went hard right on the border because organic voter demands in the lead up the election meant They Had No Choice and were just Calling Trump’s Bluff

This is getting beyond ridiculous

by the way, the obvious trick here is they measured a whole bunch of individual issues then only and specifically when asking about trans people did they position us against "helping the middle class." literally the only question juiced with that push polling technique.