How does the face form? Why do faces look different? We leverage the strengths of the zebrafish system to understand craniofacial development and variability.

Joined December 2016
28 Photos and videos
Nichols Lab retweeted
The sclerotome is the source of the dorsal and anal fin skeleton and its expansion is required for median fin development Read this #OpenAccess Research Article by Raisa Bailon-Zambrano, James Nichols @NicholsLab and colleagues: doi.org/10.1242/dev.203025
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This a special one for us, I found this weird mutant without a dorsal fin close to 15 years ago while a postdoc with Chuck Kimmel @uoregon Ultra talented @BailonRaisa uncovered a complete story as my first PhD student. Back burner projects can pay off. journals.biologists.com/dev/…

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Rae is so talented!
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Replying to @SocDevBio
@SocDevBio #ChooseDev Fellow Raelyn Begay presenting her poster to judge (l) and @clawedfeet (r) @SACNAS #NDISTEM2024. Rae is recipient of a SACNAS travel award to present the poster.
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Nichols Lab retweeted
its REAL im an #nsf grfp fellow!!
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Big congratulations to Grace Gustafson for earning an NSF GRFP! She’s an outstanding scientist that really deserves this award. #creative #smart 🐟🧬#nsf #grfp @molbcu
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We had a very fun lab ski day yesterday! Work hard play hard
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Join us in colorful Colorado. It’s a great place to work, and a fantastic place to live.
Attention craniofacial and oral biology researchers! We are looking to hire a new faculty member (at the rank of Assistant Professor) to join our collegial, research-intensive Department. Job posting: cu.taleo.net/careersection/2…
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Nichols Lab retweeted
Don't miss the next #SDBPostdocSeminar this Friday, May 12 at 3pm ET featuring Elisa Zhang @ElisaTZhang from @Stanford and Stanley Michi Kanai @KanaiMichi from @CUAnschutz. Register today and join us. bit.ly/3n1yrKY
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New paper from the lab. Distinct and redundant roles for zebrafish her genes during mineralization and craniofacial patterning frontiersin.org/articles/10.…

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Check out the remarkable mineralization phenotype in zebrafish her9 mutants: Osteoblasts develop at the correct time and place, but mineralization is only very weak, or not detectable. Cartilage is largely unaffected in mutants.
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Thanks to @StenzelAmanda @AbiMumme @SucharovJuliana @MorusMit @AppelLabCU for their hard work on this project. Two helpful reviewers strengthened the paper too.
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Cheers to the best colleague anyone could ever hope for!
Here are @NicholsLab and I celebrating our six year lab anniversary @CUAnschutz in the lovely new restaurant on campus! It's been a real pleasure navigating new PI life together.
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Yeah Julio! He has made some interesting discoveries already and will show his cool fish skeletons at the conference.
To start off our series, we have Julio Jaime. He is a ✨CU Denver MARC Scholar✨ and an undergraduate in the @NicholsLab. 🐟🐠🐟
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Seeking to understand craniofacial variation we found 1) standing variation in paralog expression levels. 2) paralog expression levels are heritable 3) variation in paralog expression can modify phenotypes associated with mutation of one of the paralogs.
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Special thanks to @SucharovJuliana for keeping this work going during the pandemic and to @BailonRaisa and @AbiMumme for seeing it through to the end!
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Apply for this faculty position in our terrific department! Colorado is a fantastic place to live and work. nature.com/naturecareers/job…

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Nichols Lab retweeted
Attention craniofacial and oral biology researchers! We are looking to hire 1-2 faculty (at the Assistant or Associate level) to join our collegial, research-intensive Department. Job posting: nature.com/naturecareers/job…

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Nichols Lab retweeted
🌞Today is the last chance to register for the 45th Annual SCGDB meeting in La Jolla, CA! Don't miss the exciting program including @Marcucio_Lab @lamsciworld @elizjleslie @LiciaSelleri @LindstromLab @Fantauzzo_Lab @sarah_m_knox @NicholsLab AND MORE! scgdb.org/annual-meeting
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