Cell biologist working in Copenhagen. Opinions are my own
Joined September 2017
- Tweets 1,399
- Following 236
- Followers 1,056
- Likes 2,210
107 Photos and videos
Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. nature.com/articles/s41594-0…
1
8
27
1,474
Feb 20
Looking forward to a great line up of speakers at #CRISPRMED26 in Copenhagen: linkedin.com/pulse/crisprmed…
Come join us for some excellent science in the heart of Copenhagen - still places available
2
106
Jakob Nilsson retweeted
7 Nov 2024
We are very excited to open the registration for the upcoming @EMBOevents on Chromosome Segregation and Aneuploidy in beautiful Stresa!!! You can find all the relevant info at meetings.embo.org/event/25-a…
Hope to see many of you in a few months!! 🧬🔬😍
#ChromoPloidy25
2
24
95
8,838
Jakob Nilsson retweeted
24 Oct 2024
The deadline for applications is approaching!!!
2 Oct 2024
Dear colleagues, we have a postdoctoral opening financed by the ERC_AdG project INTETOOLS @ERC_Research. Retweets much appreciated !!!
see the link below for details 👇
candidate.hr-manager.net/App…
Deadline for applications 6-11-24
6
8
2,896
Jakob Nilsson retweeted
23 Oct 2024
Our latest work from lab member jimmy Ly! This fundamentally changed the way we see mitosis. Massive rewiring of translational control. There is something for everyone and an amazing mechanism. Check it out.
23 Oct 2024
Cells make variants of thousands of proteins. These variants are not produced indiscriminately, but rather through precise regulatory mechanisms that can meet rapidly changing needs of the cell. New work from @iaincheeseman's lab in @Nature: wi.mit.edu/news/elegant-swit… @MITBiology
8
36
147
21,663
Jakob Nilsson retweeted
21 Oct 2024
We (@alexholehouse and @ProteinMagnus) started IDPSeminars in May 2020. It has been a wonderful platform to host an incredible array of international science. What began as a pandemic alternative to conferences has blossomed into a consistent and supportive community.
2
6
28
9,737
Jakob Nilsson retweeted
2 Oct 2024
Just a few hours into the new year, and the first paper of the year involving our lab has been published🥳
Read about the substrate specificity of the B55 subunit of PP2A and its inhibitor we designed.
Great collaboration with @NilssonLabCph, @KettenbachLab and @torbenheick labs!
2
2
7
755
Jakob Nilsson retweeted
Happy to have been a part of this collaboration with @NilssonLabCph @OraFurman @KettenbachLab @jp_arulanandam. Nice to see it finally out!
Substrate recognition principles for the PP2A-B55 protein phosphatase | Science Advances science.org/doi/10.1126/scia…
1
2
7
767
3 Oct 2024
Our paper on PP2A-B55 substrate recognition out now. Great collaboration with @FurmanLab @torbenheick @KettenbachLab @jp_arulanandam. We integrate AlphaFold modelling and protein design with biochemical and cell based assays
science.org/doi/10.1126/scia…
2
10
39
2,617
3 Oct 2024
Using this inhibitor we find that it blocks the function of the NEXT complex, a complex involved in nuclear RNA quality control. Consistent with this we find that PP2A-B55 directly binds the RBM7 component of the complex.
1
1
241
3 Oct 2024
An interesting observation for those interested in PP2A-B55 biology is that PME1, the enzyme that removes the C-terminal methyl group on the catalytic subunit causing inactivation of PP2A-B55, contains an N-terminal helix binding directly to B55.
1
213
23 Sep 2024
Base editing screen targeting all feasible S/T/Y residues (close to 600.000) to investigate phospho-dependent signaling.
biorxiv.org/content/10.1101/…
3
23
1,874
The @duxin_lab , with @NilssonLabCph, uncover #PolK's dual roles in #DNAdamage bypass. Using #CRISPR & #Xenopuseggextracts, they show PolK’s catalytic & non-catalytic functions -repairing minor groove lesions and aiding Polζ in overcoming #chemotherapeutic-induced DNA lesions!⬇️
1
5
24
2,138
19 Sep 2024
Goodbye Seefeld. Great meeting on protein networks and signalling. Good to catch up with many great scientists and meet new.
5
374
19 Sep 2024
Great work from the @duxin_lab - happy that we could make a contribution with base editing screen and some none froggy experiments:-)
nature.com/articles/s41594-0…
1
11
458
Jakob Nilsson retweeted
14 Sep 2024
Remember to submit your abstracts before Oct 1st for our conference on biomolecular condensates May, 2025
events.au.dk/biomolecular-co…
13 Aug 2024
Would you see your name in this list of illustrious speakers?
Then we need your abstract before October 1st! We will close the abstract submission and select attendees for our wonderful meeting on biomolecular condensates on this date.
events.au.dk/biomolecular-co…
9
33
4,987
Jakob Nilsson retweeted
12 Sep 2024
Have you ever wondered how many of the human SLiMs are required for cell viability? We mutated them all to find out in another extremely fun collaboration with the @NilssonLabCph group. The results are now on bioRxiv biorxiv.org/content/10.1101/…. Check it out!
11
25
2,945