𝐉𝐮𝐬𝐭 𝐨𝐮𝐭: 𝐀 𝐧𝐞𝐰 𝐚𝐩𝐩𝐫𝐨𝐚𝐜𝐡 𝐭𝐨 𝐢𝐝𝐞𝐧𝐭𝐢𝐟𝐲𝐢𝐧𝐠 𝐞𝐚𝐫𝐥𝐲 𝐟𝐢𝐛𝐫𝐨𝐭𝐢𝐜 𝐥𝐮𝐧𝐠 𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐢𝐧 𝐥𝐮𝐧𝐠 𝐜𝐚𝐧𝐜𝐞𝐫 𝐬𝐜𝐫𝐞𝐞𝐧𝐢𝐧𝐠. Expanded detection of early fibrotic phenotypes using lobar traction bronchiolectasis in lung cancer screening 𝘈𝘳𝘦 𝘤𝘶𝘳𝘳𝘦𝘯𝘵 𝘤𝘭𝘢𝘴𝘴𝘪𝘧𝘪𝘤𝘢𝘵𝘪𝘰𝘯 𝘴𝘺𝘴𝘵𝘦𝘮𝘴 𝘶𝘯𝘥𝘦𝘳𝘦𝘴𝘵𝘪𝘮𝘢𝘵𝘪𝘯𝘨 𝘤𝘭𝘪𝘯𝘪𝘤𝘢𝘭𝘭𝘺 𝘮𝘦𝘢𝘯𝘪𝘯𝘨𝘧𝘶𝘭 𝘥𝘪𝘴𝘦𝘢𝘴𝘦—𝘢𝘯𝘥 𝘮𝘪𝘴𝘴𝘪𝘯𝘨 𝘵𝘩𝘦 𝘸𝘪𝘯𝘥𝘰𝘸 𝘧𝘰𝘳 𝘦𝘢𝘳𝘭𝘺 𝘥𝘦𝘵𝘦𝘤𝘵𝘪𝘰𝘯 𝘰𝘧 𝘢𝘯 𝘐𝘓𝘈? 𝙏𝙝𝙞𝙨 𝙨𝙩𝙪𝙙𝙮 𝙨𝙪𝙜𝙜𝙚𝙨𝙩𝙨 𝙩𝙝𝙚 𝙖𝙣𝙨𝙬𝙚𝙧 𝙢𝙖𝙮 𝙗𝙚 𝙮𝙚𝙨. By focusing on traction bronchiolectasis as an early imaging marker of fibrosis, the proposed approach identifies substantially more patients with undiagnosed fibrotic ILD. As lung cancer screening continues to scale, incidental interstitial findings will only become more common. The field will need imaging frameworks that are not only sensitive, but also reproducible and clinically meaningful. Congratulations to all of the authors on this important contribution, including OSIC’s UK-based radiology lead, Prof. Joseph Jacob, @UCL Centrefor Medical Image Computing (CMIC)! academic.oup.com/ajrccm/adva… #ILD #PulmonaryFibrosis #LungCancerScreening #ThoracicImaging #Radiology #Pulmonology #ClinicalResearch #EarlyDetection #Pharma #MedTech #OSICILD

𝐓𝐡𝐞 𝐋𝐮𝐧𝐠 𝐋𝐚𝐛 𝐏𝐨𝐝𝐜𝐚𝐬𝐭 25 𝑌𝑒𝑎𝑟𝑠 𝑖𝑛 𝑃𝑢𝑙𝑚𝑜𝑛𝑜𝑙𝑜𝑔𝑦: 𝐷𝑟. 𝐿𝑖𝑠𝑎 𝐿𝑎𝑛𝑐𝑎𝑠𝑡𝑒𝑟 𝑜𝑛 𝑇ℎ𝑒 𝐿𝑜𝑛𝑔 𝑅𝑜𝑎𝑑 𝑡𝑜 𝐷𝑖𝑎𝑔𝑛𝑜𝑠𝑖𝑠 In this insightful episode, Dr. Lisa Lancaster—Chief Medical Officer at @EndeavorBioMed and Interstitial Lung Disease Program Director at @VUMCDiscoveries —joins Elizabeth Estes to reflect on 25 years in pulmonology and the challenges patients face on the path to diagnosis. From missed signs to delayed answers, they explore what’s changing—and what still needs to improve. This conversation offers perspective, progress, and hope for a future where pulmonary fibrosis is caught earlier and treated more effectively. #PulmonaryFibrosis #Pulmonology #LungHealth #RareDisease #HealthcareInnovation #PrecisionMedicine #OSICILD

𝐖𝐞’𝐫𝐞 𝐡𝐨𝐧𝐨𝐫𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐭𝐡𝐚𝐭 𝐭𝐡𝐞 𝐎𝐩𝐞𝐧 𝐒𝐨𝐮𝐫𝐜𝐞 𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐂𝐨𝐧𝐬𝐨𝐫𝐭𝐢𝐮𝐦 (𝐎𝐒𝐈𝐂) 𝐡𝐚𝐬 𝐛𝐞𝐞𝐧 𝐧𝐚𝐦𝐞𝐝 𝐚 𝐟𝐢𝐧𝐚𝐥𝐢𝐬𝐭 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐅𝐢𝐞𝐫𝐜𝐞 𝐁𝐢𝐨𝐭𝐞𝐜𝐡 𝐎𝐮𝐭𝐬𝐭𝐚𝐧𝐝𝐢𝐧𝐠 𝐀𝐰𝐚𝐫𝐝𝐬. OSIC was built to solve a problem. In rare lung disease, data were fragmented, inconsistent, and difficult to use at scale. And although progress has been made, it feels slower than it should be. So we chose a path rooted in collaboration, shared governance, and learning openly from both successes and failures, with the belief that better infrastructure can unlock better science. What has emerged is more than a database, it’s a growing intelligence platform that helps turn imaging and clinical data into something structured, reproducible, and usable for real progress in drug development. But the reason we do this has never changed....It is for the patients, families, and caregivers who do not have time to wait for the system to catch up. We are committed to radical progress for them! We are deeply grateful to the global community of investigators, partners, and contributors who have built this with us. And we are honored to be recognized alongside others working to push what is possible in biotech. Meet the Fierce Outsourcing Awards 2026 Finalists! loom.ly/W7ymwz0 #OSICILD

𝐓𝐡𝐞 𝐋𝐮𝐧𝐠 𝐋𝐚𝐛 — 𝐚 𝐧𝐞𝐰 𝐩𝐨𝐝𝐜𝐚𝐬𝐭 𝐟𝐫𝐨𝐦 𝐎𝐒𝐈𝐂. Exploring what’s next in rare lung disease. For patients. For families. For progress. Elizabeth Estes

𝐈𝐧𝐭𝐫𝐨𝐝𝐮𝐜𝐢𝐧𝐠 𝐓𝐡𝐞 𝐋𝐮𝐧𝐠 𝐋𝐚𝐛 — 𝐚 𝐧𝐞𝐰 𝐩𝐨𝐝𝐜𝐚𝐬𝐭 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐎𝐩𝐞𝐧 𝐒𝐨𝐮𝐫𝐜𝐞 𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐂𝐨𝐧𝐬𝐨𝐫𝐭𝐢𝐮𝐦 (𝐎𝐒𝐈𝐂). Over the past several years, OSIC has worked alongside researchers, clinicians, and patients across the rare lung disease community. Along the way, we’ve seen both meaningful progress and the real challenges that still remain. 𝐓𝐡𝐞 𝐋𝐮𝐧𝐠 𝐋𝐚𝐛 is a space to explore those realities. Each episode looks at how rare and progressive lung diseases are being understood today and where things may be heading next, from earlier detection to new approaches in treatment. The goal is simple: to bring together the people and ideas shaping what comes next, and to make that conversation more accessible. This work is grounded in something bigger….the need to make real, and hopefully, radical progress on behalf of patients, caregivers, and families who are living with these diseases every day. In our first episode, OSIC’s Executive Director, Elizabeth Estes, shares 𝑾𝒉𝒂𝒕 𝑰𝒇 𝑾𝒆 𝑪𝒐𝒖𝒍𝒅?—𝒕𝒉𝒆 𝒔𝒕𝒐𝒓𝒚 𝒃𝒆𝒉𝒊𝒏𝒅 𝒕𝒉𝒆 𝒅𝒆𝒗𝒆𝒍𝒐𝒑𝒎𝒆𝒏𝒕 𝒐𝒇 𝒂 𝒈𝒍𝒐𝒃𝒂𝒍 𝒍𝒖𝒏𝒈 𝒊𝒎𝒂𝒈𝒊𝒏𝒈 𝒂𝒏𝒅 𝒄𝒍𝒊𝒏𝒊𝒄𝒂𝒍 𝒅𝒂𝒕𝒂𝒔𝒆𝒕, 𝒂𝒏𝒅 𝒘𝒉𝒂𝒕 𝒊𝒕 𝒄𝒐𝒖𝒍𝒅 𝒎𝒂𝒌𝒆 𝒑𝒐𝒔𝒔𝒊𝒃𝒍𝒆. New episodes will be released every other week over the next three months, featuring voices from across research, medicine, and technology. 𝐍𝐞𝐱𝐭 𝐮𝐩: 𝐃𝐫. Lisa Lancaster, Chief Medical Officer at @EndeavorBioMed and Interstitial Lung Disease Program Director at @VUMCDiscoveries. osicild.org/podcast/ #TheLungLab #OSICILD #LungHealth #Podcast #LungDisease

👏 Congratulations on the excellent @Nature article, @OSICild! We are encouraged by the progress, and proud to play a role in pursuing your mission in #ILD. linkedin.com/posts/ild-share…

Thanks to Neil Savage and @naturemagazine for this article that explores recent advancements aimed at improving the diagnosis and treatment of lung diseases, and highlights how data from our repository is helping researchers better understand #IPF and deliver more accurate prognoses. With #AI enhancing imaging analysis, earlier detection and better monitoring of disease progression are becoming possible. Enhanced screening and AI-driven assessments are paving the way for more personalized treatments. Together, these innovations offer hope for earlier intervention, improved patient management, and a better understanding of lung diseases. We’re proud to be advancing #ILD and rare lung disease research, driving breakthroughs that bring hope to patients worldwide. nature.com/articles/d41586-0…

May this coming year bring you healthy days, happy weeks, and countless opportunities for growth and innovation. We're excited to see all the great things we'll accomplish together in the months ahead! HAPPY NEW YEAR!

New Frontiers for Progress: Catalyzing Breakthroughs in Lung Disease OSIC’s Annual Member Meeting is coming to Amsterdam! Join us on September 27 for an afternoon of discovery: - Bronchiectasis: The Next Therapeutic Frontier – How imaging, phenotyping, and AI are redefining this once-overlooked condition. Dr. Kevin Brown, Dr. Helmut Prosch, Dr. Luca Richeldi. - Sarcoidosis: From Complexity to Clarity – With Elise Hoover (Foundation For Research @StopSarcoidosis ), unveiling global registry efforts and AI collaborations. - Generative AI in Action – Featuring Dr. David Barber (@ucl ), showing how AI can predict disease progression earlier and build cross-disease models. - OCT Imaging Spotlight – Dr. Lida Hariri on in vivo lung microstructure, the “virtual biopsy” of fibrosis. - Exploring New Features and Advanced Filters in the OSIC Cloud – Sandra Stapleton (VIDA). - Member Success Stories – See how leading companies like @CorelineSoft , GMV, @ThisIsThirona , and @Brainomix are using OSIC data to accelerate innovation. Don’t miss this chance to see how OSIC is turning data into discovery. #AIinHealthcare #LungDisease #Bronchiectasis #Sarcoidosis #GenerativeAI #MedicalImaging #DigitalHealth #RareDisease #ClinicalAI #OSICILD #CollaborationForCure #ERS2025 See full agenda and meeting details: osicild.org/events/membermee…

September is Pulmonary Fibrosis Awareness Month, a time to bring attention and support to the thousands of patients and caregivers around the world living with this chronic – and incurable – lung disease. At OSIC, we are passionately committed to making radical progress for those living with #PF and other #ILDs. Through the power of collaboration and innovation, we know we can get there. Thank to you all of our partners for their commitment to our mission. Join us in raising awareness this September. Together, we can accelerate research, enhance treatment, and improve lives. #PFMonth #CurePF #PulmonaryFibrosisAwareness #ILD