We investigate the role of the ubiquitin and the interferon/ISG15 system in maintening genome stability in response to different types of stress
Joined February 2023
- Tweets 28
- Following 176
- Followers 194
- Likes 23
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Lorenza Penengo Lab retweeted
20 Jun 2024
š¢Excited to share the latest work from the Santoro Lab ! A cutting-edge technology reveals the crucial role of the nucleolus in genome organisation. Discover more: biorxiv.org/content/10.1101/ā¦ #Genomics #Nucleolus"
20 Jun 2024
New exciting data from the lab! We established nucleolar laser microdissection (NoLMseq) to capture single-cell dynamics of genome-nucleolus interactions in normal and āstressedā nucleoli, providing novel insights into genome organization & function biorxiv.org/content/10.1101/ā¦
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Lorenza Penengo Lab retweeted
23 Jan 2024
So exciting to see this amazing story out!!
Glad I could be of help š
Huge shout-out to all authors involved šš
A highly recommended read for all DSBs and DNA repair aficionaf@s!!
23 Jan 2024
It is online! The first paper of the Noordermeer lab. Of course, this wasn't possible without the help of many others (see thread for more details). Congratulations to first authors @BertKooij, Anne Schreuder and @pavani_raphael.
sciencedirect.com/science/arā¦
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Lorenza Penengo Lab retweeted
9 Nov 2023
Researchers from the group of @FMattiroli developed a new fluorescence-based assay and used this to identify ANP32B as the histone chaperone responsible for the histone macroH2A. First author @IMandemaker tells all about it here! hubrecht.eu/histones-and-chaā¦
ALT Microscopy image of human cells stained for macroH2A and DNA.
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Lorenza Penengo Lab retweeted
7 Nov 2023
The final countdown has begunā¦ a week more for the closing of registrationsā¦ please register soon as only a few more slots are leftš„š
31 Oct 2023
Just a few more days to go for the registration deadline- āEMBO workshop on evolution and diversity of the DNA damage responseā meetings.embo.org/event/24-dā¦ multiple short talks, & waivers available! š§¬Donāt miss this amazing opportunity to meet with world leaders & journal editors.āļø
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Lorenza Penengo Lab retweeted
7 Nov 2023
Happy to share our recent publication identifying a vulnerability in ALT #cancer cells that can be targeted by #telomeric #antisenseoligonucleotides #ASO against #ncRNA induced by #telomere dysfunction.
nature.com/articles/s41467-0ā¦
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Lorenza Penengo Lab retweeted
20 Oct 2023
We are looking for DNA replication enthusiast to join our group as a postdoctoral researcher. If you are into biochemistry, cell biology, structural biology in replication and damage, please get in touch, or apply - the link below. Closing date 9th November. RT pls
20 Oct 2023
š¢Research Fellow wanted to create & contribute to the creation of knowledge by undertaking research specified by BBSRC research grant awarded to @AgaGambus to investigate function of DONSON during DNA replication initiation. shorturl.at/ghnGX
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2 Oct 2023
ONLINE NOW our story on the role of interferon/ISG15 in BRCA contexts! Congratulations to Ramona Moro, @uddipta_biswas, and all the co-authors! A great collaborative effort with Shyam Sharan, @RFreireLab and @Arnab_RC1.
nature.com/articles/s41467-0ā¦ Thrilled to hear your feedback!
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Lorenza Penengo Lab retweeted
28 Mar 2023
Excited to announce our new paper by @EsperanzaHC_ in @NAR_Open, showing a new role for ATXN3 in regulating chromatin structure by controlling the subcellular localization of HDAC3 and thereby giving insight into the molecular basis of SCA3.
doi.org/10.1093/nar/gkad212
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Lorenza Penengo Lab retweeted
24 Mar 2023
A new substrate for Telomerase?
By visualizing telomerase activity on telomeric replication forks we provide strong evidence in support of a hypothesis that has been lingering for a while in the field. @ScienceAdvances @luchenlab_FCCC
science.org/doi/10.1126/sciaā¦
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20 Mar 2023
After first showing some of these new, exciting data from the lab @CSHL Replication 2021, we now share a full story on the impact of IFN signaling and ISG15 on replication fork integrity, proliferation and chemoresistance in BRCA-deficient cells biorxiv.org/content/10.1101/ā¦ Please RT!
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20 Mar 2023
Great collaborative effort with Shyam Sharan and @Arnab_RC1. Thrilled to hear opinions and suggestions!
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20 Mar 2023
Important follow-up of the first link between ISG15 and replication fork progression that we reported in 2020 pubmed.ncbi.nlm.nih.gov/3259ā¦
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8 Mar 2023
Excited about the next speaker at our Monday Seminar (MoSe) series!!
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