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Joined June 2014
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20 Jan 2025
What if science truly is like volleyball, where teamwork and support are everything? We spoke with Francesca Mattiroli, who recently earned tenure, to explore this question and more. Read her inspiring story here š hubrecht.eu/francesca-mattirā¦
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9 Jan 2025
On Jan 9, dr. Henriette van Beijnum defended her PhD on the regenerative abilities of the spiny mouse. Congratulations! Her findings, like the flexible ābasket-weaveā scar pattern, could help improve treatments for heart attacks and chronic wounds. See hubrecht.eu/phd-defense-henrā¦
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2 Jan 2025
Researchers from @BakkersLab have successfully repaired damaged mouse hearts using a protein from zebrafish. This study marks a promising step toward regenerative therapies to prevent heart failure. Read more hubrecht.eu/zebrafish-proteiā¦
@DEMdeBakker
@BouwmanMara
@J_Bakkers
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30 Dec 2024
Researchers from the @TheCleversLab developed a method to grow organoids using a bacterial protein: Invasin. The study, published today in @PNASNews, shows that Invasin offers a sustainable, affordable and animal-free alternative to current methods. hubrecht.eu/Invasin-protein-ā¦
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20 Dec 2024
How reliably is the epigenome passed from one cell to its daughter cells? @AlexandervanOu1, @jervdberg, @groth_anja & @Lleonie received a @novonordiskfond grant to answer this question, which will lead to new strategies to prevent disease and combat aging hubrecht.eu/novo-nordisk-epiā¦
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10 Dec 2024
The inaugural Hubrecht Symposium is on March 13th, 2025! Join an inspiring day on molecular & developmental biology. This annual event highlights the role of fundamental research in Dutch science. Free of charge! Submit your abstract by February 13th. See hubrecht.eu/hubrecht-symposiā¦
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3 Dec 2024
Congratulations to dr. Yasmine El Azhar, who successfully defended her thesis: Notch signalling dynamics during mouse development and homeostasis. She developed a mouse model to visualize real-time Hes1 oscillations in single cells @SonnenKatharina group. hubrecht.eu/phd-defense-yasmā¦
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Hubrecht Institute retweeted
3 Dec 2024
Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineagesā. cell.com/cell/fulltext/S0092ā¦ 1/
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Hubrecht Institute retweeted
3 Dec 2024
š¢New human fetal pancreatic organoid model generates all three key cell types of the pancreas. New paper in @CellCellPress by @AmandaARolf , @HansClevers and collaborators. See the article here: sciencedirect.com/science/arā¦
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2 Dec 2024
Researchers from @TheCleversLab created an organoid that mimics the human fetal pancreas. Unlike previous models, this organoid has all three key cell types. They also identified the stem cell that develops into these cells. Curious? hubrecht.eu/researchers-creaā¦
@AmandaARolf @Roche
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21 Nov 2024
š§¬New research published @NatureComms reveals how cells fix damaged DNA. Researchers from the @kind_jop group mapped repair proteins and show how they form 'hubs,' to coordinate repairs, almost like a 'repair cafĆ©'. Learn more: hubrecht.eu/dna-repair-proteā¦ #DNARepair #SingleCell
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12 Nov 2024
Researchers from the Mattiroli group discovered that DNA packaging in cells can directly impact the speed of DNA copying during cell division. The packaging sends signals through an unusual pathway, affecting the cellās ability to divide and grow. More: hubrecht.eu/dna-packaging-diā¦
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1 Nov 2024
Our position for tenure-track principal investigator is still open! As junior group leader you will develop your research line within our lively scientific community. Ready to establish your own research group at the Hubrecht Institute? Apply before 15-11! hubrecht.eu/job/tenure-trackā¦
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1 Nov 2024
Researchers from the Organoid group have developed a new organoid model to study the origin of colorectal cancer. The researchers studied the sequential accumulation of mutations contributing to tumor formation. @HansClevers @Tom_Mizutani Read more here: hubrecht.eu/organoid-colorecā¦
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24 Oct 2024
Francesca Mattiroli, group leader, receives a Vidi grant from the Dutch Research Council (NWO). With this funding, she and her team will investigate how DNA and its packaging are copied during cell division. Their findings could in the future help in fighting diseases and aging.
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18 Oct 2024
Congratulations to all researchers on this great new paper in @ScienceMagazine, including @BeumerJoep @geurts_maarten @VeerleGeurts @NinoukAkkerman @DanielKruegerDK @JensPuschhof, in collaboration with @Roche @IHB_Research @MaastrichtU @UMCUtrecht
18 Oct 2024
New @ScienceMagazine study in collab with @IHB_Research!
We identified novel receptors on enteroendocrine cells (EECs) that regulate secretion of endogenous hormones. These harbor therapeutic potential for metabolic disease. Read the paper go.roche.com/m9hahĀ or š§µā¬ļø
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17 Oct 2024
A team from the Organoid group and @IHB_Research @Roche has uncovered nutrient sensors on gut hormone-producing cells using organoids. The characterization of these sensors will help in treating metabolic & gut motility disorders. @BeumerJoep @HansClevers hubrecht.eu/intestinal-nutriā¦
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Hubrecht Institute retweeted
11 Oct 2024
Super happy to see this heroic effort by @DimitriFabreges and Bernat Corominas out! Via a quantitative atlas of the developmental trajectories of dozens of embryos, we can see how robust shapes and fates arise from highly stochastic cellular processes! science.org/doi/10.1126/scieā¦ 1/n
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