computational biologist | Postdoctoral fellow in the Bernstein lab @DFCI_CancerBio @broadinstitute | Ph.D. graduate @TiroshLab @WeizmannScience

Joined November 2012
Photos and videos
Huge congrats Alissa and good luck! Highly recommend checking out her new lab at University of Toronto!
I'm thrilled to share that I'll be starting my lab (greenwald-lab.org) at the Lunenfeld-Tanenbaum Research Institute @SinaiHealth and joining @MoGen_Grad at the University of Toronto as an assistant professor this fall. 1/
1
1
319
Rony Chanoch-Myers 🎗️ retweeted
1/ Truly excited to share our new study that I had to privilege to co-lead during my PhD alongside great friends and collaborators @M_Nomura, Kevin C. Johnson and Luciano Garofano, which was published @NatureGenet! nature.com/articles/s41588-0…

3
29
103
9,239
Rony Chanoch-Myers 🎗️ retweeted
Goodbye, Shiri, Kfir, and Ariel (credit: Shoshke Engelmayer) 💔🎗️
1
4
195
Excited to share our new paper out in @CD_AACR! We developed GCOs—glioblastoma cells grown in human cortical organoids—and used scRNA-seq to show their increased fidelity to patient cell states. Plus, we found tumor cells transfer malignant mRNAs to non-malignant cells!
Now online in @CD_AACR: #Glioblastoma-Cortical #Organoids Recapitulate Cell State Heterogeneity and Intercellular Transfer - by Vamsi Mangena, @RChanoch, Paola Arlotta, @tiroshlab, @MarioSuva, & colleagues doi.org/10.1158/2159-8290.CD… @broadinstitute @weizmannscience @MGHCancerCenter
2
5
21
2,984
A fantastic collaboration with co-first author Vamsi Mangena, under the guidance of Paola Arlotta, @TiroshLab, & @MarioSuva! 🚀
5
108
Rony Chanoch-Myers 🎗️ retweeted
Congrats to @MarioSuva lab, @TiroshLab, and @ArlottaLab, especially Vamsi and @RChanoch! A GBM cortical organoid model that not only recapitulates the core GBM cancer cell states, but also recapitulates intercellular communication between cancer cells and the TME via EVs! Having good model systems of intercellular communication will be great for functional studies. Really cool that this seems to be a more generalizable phenomenon (also observed in breast cancer cells engrafted in cortical organoids, mimicking brain mets) & very interesting as a model to further explore how cancer cells dynamically modulate their local environment.
Now online in @CD_AACR: #Glioblastoma-Cortical #Organoids Recapitulate Cell State Heterogeneity and Intercellular Transfer - by Vamsi Mangena, @RChanoch, Paola Arlotta, @tiroshlab, @MarioSuva, & colleagues doi.org/10.1158/2159-8290.CD… @broadinstitute @weizmannscience @MGHCancerCenter
6
19
2,381
Rony Chanoch-Myers 🎗️ retweeted
I’m very happy to share our paper in @CellCellPress on the spatial organization of GBM! bit.ly/4aKDeEp. Check out our tweetorial for a summary of our findings: bit.ly/44e0uZ9. I wanted to share a few additional thoughts on its implications and some future directions. 1/
7
19
124
27,026
Amazing work!
23 Apr 2024
Excited to share our new paper in @CellCellPress on spatial organization in glioblastoma authors.elsevier.com/c/1izT9…. We combine spatial transcriptomics (Visium) and proteomics (CODEX) to reveal five-layer organization of cellular states and a role of hypoxia as tissue organizer. 1/
2
135
Rony Chanoch-Myers 🎗️ retweeted
1/ We are extremely excited to share our new manuscript published @Cancer_Cell! Kudos to co-first authors @AvishaySpitzer, @GritschSimon and @M_Nomura for seminal work, to co-PIs @MarioSuva, Dan P. Cahill and @KeithLigon5 and to all contributors.
Online Now: Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma dlvr.it/T57X2F
8
30
138
28,773
Rony Chanoch-Myers 🎗️ retweeted
Preview of one of my PhD projects @TiroshLab @WeizmannScience that was published today @Cancer_Cell. Delighted to see this go online!
Online Now: Shifting the landscape: The role of IDH inhibitors in glioma cell fate dlvr.it/T54Vc2
3
5
36
2,325
Rony Chanoch-Myers 🎗️ retweeted
The presidents of @Harvard, @MIT, and @Penn were all asked the following question under oath at today’s congressional hearing on antisemitism: Does calling for the genocide of Jews violate [your university’s] code of conduct or rules regarding bullying or harassment? The answers they gave reflect the profound moral bankruptcy of Presidents Gay, Magill and Kornbluth. Representative @EliseStefanik was so shocked with the answers that she asked each of them the same question over and over again, and they gave the same answers over and over again. In short, they said: It ‘depends on the context’ and ‘whether the speech turns into conduct,’ that is, actually killing Jews. This could be the most extraordinary testimony ever elicited in the Congress, certainly on the topic of genocide, which to remind us all is: “the deliberate killing of a large number of people from a particular nation or ethnic group with the aim of destroying that nation or group” The presidents’ answers reflect the profound educational, moral and ethical failures that pervade certain of our elite educational institutions due in large part to their failed leadership. Don’t take my word for it. You must watch the following three minutes. By the end, you will be where I am. They must all resign in disgrace. If a CEO of one of our companies gave a similar answer, he or she would be toast within the hour. Why has antisemitism exploded on campus and around the world? Because of leaders like Presidents Gay, Magill and Kornbluth who believe genocide depends on the context. To think that these are the leaders of Ivy League institutions that are charged with the responsibility to educate our best and brightest. On the bright side, our congressional leaders deserve accolades for showing tremendous leadership and moral clarity in their statements, by the questions they asked, and the respectfulness with which they conducted the hearing. It was a masterclass of how our government and democracy should operate. If you have time, please watch the entire hearing. Throughout the hearing, the three behaved like hostile witnesses, exhibiting a profound disdain for the Congress with their smiles and smirks, and their outright refusal to answer basic questions with a yes or no answer.
23,266
39,698
129,235
107,946,852
Rony Chanoch-Myers 🎗️ retweeted
They raped Israeli women. They murdered Israeli women. They kidnapped Israeli women. Yet @UN_Women organizations have been SILENT since October 7th. Ahead of the @UN’s International Day for the Elimination of Violence against Women we promise to make sure the voices of Israeli women are heard around the world. Please sign this petition- metoo-unlessurajew.com #Oct7Massacre #MeToo_UNless_UR_a_Jew #BelieveIsraeliWomen
721
2,520
6,636
1,217,978
Rony Chanoch-Myers 🎗️ retweeted
A short letter we wrote. I wish people would listen. I wish academia to be what it can and should be. A place where terror is condemned, and everyone feels safe. And most of all, I wish for the hostages to be released. Bring them home, make it stop! 😢 nature.com/articles/d41586-0…

2
28
94
8,601
Rony Chanoch-Myers 🎗️ retweeted
On October 7th, 1,400 men, women, children and babies were murdered by Hamas terrorists who went door to door butchering entire families. There is now an interactive map which provides a comprehensive representation of the atrocities committed by Hamas on that day. Please visit the website and pay tribute to the victims and their families whose lives have been destroyed. 🔗 oct7map.com
1,671
2,295
5,932
468,303
Rony Chanoch-Myers 🎗️ retweeted
28 Oct 2023
Opening monologue by @DanyCushmaro on Israel’s Channel 12 News on Friday night #bringthemhome #ReleaseTheHostages
125
654
1,868
164,757
Rony Chanoch-Myers 🎗️ retweeted
10 Jul 2023
We’re excited to share our preprint on spatial organization in glioblastoma: doi.org/10.1101/2023.07.06.5…. We combine spatial transcriptomics (Visium) and proteomics (CODEX) to reveal a five-layer organization of cellular states and highlight a role of hypoxia as tissue organizer. 1/
6
114
432
70,535
Rony Chanoch-Myers 🎗️ retweeted
1. Excited to share our new paper in @Nature! With over 1000 tumors analyzed by scRNA-seq, we provide a systematic pan-cancer characterization of transcriptional intra-tumor heterogeneity (ITH) nature.com/articles/s41586-0…
30
349
1,272
153,977
Very excited to share our work published in @GenomeMedicine on the mesenchymal state of glioblastoma! @TiroshLab @MarioSuva
New #braincancer research from @RChanoch @MarioSuva & co @WeizmannScience which combines multiple #Glioblastoma datasets to define a core mesenchymal program & highlight 3 main MES states with distinct functional, genetic & environmental associations bit.ly/3dyMfrT
3
9
27
Here, we address this by integrative analysis of multiple GBM datasets and signatures. We highlight three MES flavors: hypoxia-related (MES-Hyp), astrocyte-related (MES-Ast), and an intermediate state and find distinct genetic and environmental factors associated with them.
3