Prof. Emeritus @UC San Diego. Also Clinical Excellence Research Center, Stanford. Tech knowledge from craft to science. Currently: healthcare, flying.

Joined April 2009
153 Photos and videos
Pinned Tweet
12 Jun 2020
USA in >4 simultaneous major crises: 1 Pandemic (Worst in 100 years) 2 Major recession (100 years? Not clear yet) 3 Equality crisis (Crisis 150 years old; public pain worst in 50 years) 4 Constitutional crisis (85 years?) 5 Slow environmental crisis (worst in 20,000 years)
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AI vibe coding has major flaws. This is predictable - new technologies always have problems. Faster dissemination (aka marketed) ==> less ecosystem understanding and worse end-user effects. open.substack.com/pub/garyma…

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‘A bombshell’: doubt cast on discovery of microplastics throughout human body - The Guardian “…good laboratory practices have not necessarily been followed.” Including …blanks, repeating measurements…samples spiked with a known amount of MNPs. apple.news/AtsvOY2uKReiIe8o-….
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Roger Bohn retweeted
20 Nov 2025
This is the end. Now no one can cross this level !
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Roger Bohn retweeted
It's over, folks. Pack it in.
An M.I.T. study found that 95% of companies that had invested in A.I. tools were seeing zero return. It jibes with the emerging idea that generative A.I., “in its current incarnation, simply isn’t all it’s been cracked up to be,” @JohnCassidy writes. nyer.cm/FUZwzw8
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14 Jul 2025
Unfortunately there is no theorem that says glamorous new technologies will ultimately be beneficial for humanity. Even though in past that’s been true. Marcus predicts LLM benefits will be positive but small, while side effects will be serious. (Kind of like social networking?)
14 Jul 2025
My overall view at this point (slightly more positive than @LuizaJarovsky below) is that generative AI chatbots (distinct from domain-specific tools like AlphaFold) will on net increase productivity to a moderate degree in many domains, with large benefits in a few areas. (I also agree with all of Luiza’s cautions round the costs in making this work.) But those productivity benefits will also come with strong costs to society (misinformation undermining democracy, deep fakes for scams and politics, disruption of high school and college education, delusions that bring some to mental illness, nonconsual deepfake porn, increased cybercrime, greater surveillance, negative environmental impact, etc, to say nothing of an increasingly oligarchical society) Overall, I am not convinced that GenAI will be of significant net benefit to society. I would welcome @emollick’s latest take on this.
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Roger Bohn retweeted
14 Jul 2025
My overall view at this point (slightly more positive than @LuizaJarovsky below) is that generative AI chatbots (distinct from domain-specific tools like AlphaFold) will on net increase productivity to a moderate degree in many domains, with large benefits in a few areas. (I also agree with all of Luiza’s cautions round the costs in making this work.) But those productivity benefits will also come with strong costs to society (misinformation undermining democracy, deep fakes for scams and politics, disruption of high school and college education, delusions that bring some to mental illness, nonconsual deepfake porn, increased cybercrime, greater surveillance, negative environmental impact, etc, to say nothing of an increasingly oligarchical society) Overall, I am not convinced that GenAI will be of significant net benefit to society. I would welcome @emollick’s latest take on this.
🚨 Unpopular opinion: generative AI’s overall productivity gain is probably close to zero. Companies that want to justify their "AI-first" strategy often conveniently ignore the time, effort, and costs involved in making sure AI-assisted work meets minimal standards. They can ignore it, but the additional work will not disappear. 2026 will likely be a year of reality shocks and budget adjustments. - 👉 NEVER MISS my analyses and curations on AI: sign up for my newsletter below (67,500 subscribers).
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Roger Bohn retweeted
X (and other social media sites) make our 1990s optimism about the Information Age seem silly. Even with all of the world's information a click away (& a free AI that can help explain that information in a personalized way), half-mangled anecdotes with no source win every time.
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I just received a $48 settlement check in the "Peters v Apple" class action case. My experience with minor class actions is that few people apply, and the $ payout is therefore larger than expected. We got $300 from a minor Pet Smart #classaction Most much less.
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25 Oct 2024
Why nonviolent resistance beats violent force in effecting social, political change — Harvard Gazette. In case Trump becomes president, perhaps with a boost from his corrupt Supreme Court. Nonviolent resistance not easy, but easier than the violent kind! news.harvard.edu/gazette/sto…
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13 Oct 2024
In an SUV: raise your seat! And if possible, move it forward to further improve your view. substack.com/@speakeasy/note…

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27 Sep 2024
The level of caution about automated AI tools is way too low. Don't use new tools until you personally test them, and consider failure modes. Example here: Otter AI transcript Prediction: within 3 years, AI-connected cars used for attacks on their occupants or passers-by
A VC firm I had a Zoom meeting with used Otter AI to record the call, and after the meeting, it automatically emailed me the transcript, including hours of their private conversations afterward, where they discussed intimate, confidential details about their business.
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23 Sep 2024
Scary! Covid caused a notable drop in cognitive performance. The size was moderate - about .7 standard deviations, by eyeball. But that is from a single infection. What about after multiple infections?
SARS-CoV-2 infection causes persistent cognitive damage. 34 healthy, young volunteers were inoculated and monitored for cognitive changes over a year. They showed lower cognitive scores, w/ significant differences in memory and executive function tasks. thelancet.com/journals/eclin…
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Roger Bohn retweeted
BREAKING! @FrancescaGino's ridiculous defamation lawsuit against @DataColada from last year has been dismissed by the court! This is an important victory.. if this had been allowed to move forward it would have had a chilling effect on whistleblowers! storage.courtlistener.com/re…
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19 Aug 2024
It’s a shame that I never ran into this before. I mostly figured it out from other sources, but this captures “basic paper organization” very clearly.
In 2017 we wrote a 10-simple-rules paper to teach researchers how to structure scientific papers for clarity and impact. One million English-version downloads later ( translations) and it feels like we see its reflection in worldwide writing training. journals.plos.org/ploscompbi…
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Rodney Brooks’s 3 Laws of Robotics. Real world use completely different than academic demos! "Great-looking videos are just not the same things as working for a customer every time. Most of what we see in the news about robots is lab demonstrations." spectrum.ieee.org/rodney-bro…
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Roger Bohn retweeted
Yes, college students have lost their ability to read. I have taught lit for 24 years; the threshold started to decline in the late aughts and nosedived during Covid. A thread with observations how I get my students to read ALL (or at least most) of the reading I assign: 🧵
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Roger Bohn retweeted
The choice is simple: 1. A decent but frail old man, surrounded by a good, experienced team. 2. A bat-shit crazy old man, surrounded by a bunch of sycophant hooligans.
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