Led by Prof @Jamie_Rossjohn FRS we are focused on understanding molecular bases underpinning protective and aberrant immunity
Joined July 2014
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29 Oct 2024
In collaboration with labs
@PN0rmski @KatherineKedz @AndrewB34372462 @syctong and co-authors, paper published
@MonashUni:
An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania: Cell cell.com/cell/fulltext/S0092…
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Mar 18
🚨🧬An in vivo cell therapy engineering platform of transformative potential. Congratulations to @j_eyquem and team on a breathtaking (and groundbreaking) body of work. @parkerici @UCSF
nature.com/articles/s41586-0…
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NHMRC Investigator Grants out today.
A devastating day for many. I have already received messages from some of the best researchers I know who have missed out.
The senior levels had a cutoff of 5.93 (females), 6.2 (males) - according to my sources.
The impact will be wide spread.
The damage being done at the moment to the sector is totally unacceptable. We need to do a lot more to support our research community.
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21 Oct 2025
#StarsOfScience – Professor Jane Visvader's groundbreaking discoveries at @WEHI_research have fundamentally changed how we understand breast development and cancer.
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31 Jul 2025
Congrats to PhD student, Liam Rashleigh, whose 1st authored paper on gd T cell receptor recognition was published today @Structure_CP
cell.com/structure/fulltext/…
#GDTcellclub @MonashUni @RossjohnLab
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3 Jun 2025
Early bird registration pricing for CD1-MR1 2025 ends this Friday, 6th June! Get on it 👉👉 cd1mr1.com
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2 Jun 2025
Congrats to Hien, 1st author of this study that arose from her hard work during her PhD.
Latest research from @jbiolchem “The molecular basis of T cell receptor recognition of citrullinated tenascin-C presented by HLA-DR4” by Dao et al. jbc.org/article/S0021-9258(2… @ASBMB @Jamie_Rossjohn
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22 May 2025
In collaboration with Moody lab, latest paper from @RossjohnLab describing the structure of a lipopeptide bound to a MHC-I like molecule found in chickens - hopefully this study will not ruffle too many feathers.
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18 Apr 2025
Your immune system gradually loses it top team players when we get older 👱➡️👵
Our study in @eBioMedicine investigates how long our good immune cells stay around – a 🧵⬇️ go.unimelb.edu.au/4sep
@CvandeSandt @KatherineKedz @TheDohertyInst #Influenza #AgingResearch
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16 Apr 2025
Our latest paper demonstrating the potential of “our” DOT cells against colorectal cancer has just been published in @NatureCancer:
rdcu.be/ehYwG
Many congrats to the whole team, especially @RafaelBlancoDom! :)
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8 Apr 2025
Recent paper from lab describing a peptide-independent MHC-restricted T cell receptor nature.com/articles/s41467-0… in collaboration with La Gruta lab @MonashUni @Monash_FMNHS @RossjohnLab @NatureComms
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21 Feb 2025
In collaboration with @NicoleLaGruta1 and colleagues, latest paper from @Jamie_Rossjohn lab describing role of Lck-coreceptor assocation in T cell function. @MonashUni
science.org/doi/10.1126/scii…
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9 Feb 2025
Researchers in Science #Immunology have identified CD8 T cells from human donors that can recognize naturally occurring influenza variants spanning more than 100 years, including the 1918 influenza A and 2024 #H5N1. @Jamie_Rossjohn @kedzierskalab
scim.ag/4hpSzh1
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10 Feb 2025
🚨 Flu breakthrough! 🚨 Researchers at @TheDohertyInst & @MonashUni have discovered immune cells that recognise flu viruses even as they mutate—a further step toward a universal flu vaccine. go.unimelb.edu.au/d7z8 @UniMelbMDHS @TheRMH @oanheei @Jamie_Rossjohn @kedzierskalab @KatherineKedz
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8 Feb 2025
Our latest study @SciImmunology identifies the molecular determinants of cross-reactive B35/NP418-restricted CD8 T cells across IAVs from 1918 H1N1 to 2024 H5N1, and assesses their functionality.
@KatherineKedz @RossjohnLab
science.org/doi/10.1126/scii…
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7 Feb 2025
TCR-peptide-HLA ternary structures define molecular mechanisms of TCR cross-reactivity toward natural influenza variants @SciImmunology
science.org/doi/10.1126/scii…
@RossjohnLab @Jamie_Rossjohn @kedzierskalab @KatherineKedz
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31 Jan 2025
science.org/doi/10.1126/scii… First paper from the @JohnstoneLab for the year and a brilliant collaboration with @TheDohertyInst colleagues Dan Utzschneider and Alex Kallies. Thanks to all @PeterMacRes @PeterMacCC for help and support and great job Dane Newman and Leonie Cluse!
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26 Jan 2025
Researchers paid $8.968 billion for their findings to be freely accessible.
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17 Jan 2025
Latest paper from lab, where Awad et al describe how cigarette smoke impacts that MAIT-MR1 axis and implications for lung diseases. In collaboration with Fairlie, Hansbro and Corbett labs doi.org/10.1084/jem.20240896
@MonashBDI @nhmrc @WaelAwadMoh @MonashUni @Jamie_Rossjohn @JExpMed
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