@Ruhl_Lab profile picture
Stefan Ruhl @Ruhl_Lab

We study how #glycans in #saliva make #bacteria stick to #teeth

Joined September 2016
  • Tweets 1,122
  • Following 231
  • Followers 368
96 Photos and videos
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Stefan Ruhl@Ruhl_Lab
23 Nov 2025
A compelling write-up by Laurie Kaiser of our recent findings about the evolution of 💧💧#SALIVA 💧💧. Proud of @PetarPajic93 who led the investigation with help from @luanelandau. Grateful to Ömer @GokcumenLab, a master of evolutionary genetics. buffalo.edu/ubnow/stories/20…

Tracking evolution of human saliva back to primates

A UB study highlights how evolutionary adaptations to diet and disease may have influenced primate biology, including humans.

buffalo.edu
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🦷🦷 #TEETH ❗️🦷🦷 washingtonpost.com/science/2…

A 59,000-year-old tooth reshapes what we know about Neanderthal dentistry

Neanderthals used rock drills to treat an infected tooth, according to a study that pushes back the earliest known evidence of dentistry by more than 40,000 years.

washingtonpost.com
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Stefan Ruhl retweeted
History and Dentistry@DentalHistMag
May 8
500-year-old gold dental bridge is earliest known oral care of its kind in Scotland — and it likely held a fake tooth livescience.com/archaeology/…

500-year-old gold dental bridge is earliest known oral care of its kind in Scotland — and it likely...

Archaeologists discovered the 20-karat-gold dental wire in the lower jaw of a middle-aged man who lived around 500 years ago in Scotland.

livescience.com
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This year we went in with a strong team from University at Buffalo School of Dental Medicine @UBSDM @UB and @UofR advocating on Capitol Hill for Oral Science @NIDCR at NIH @AADOCR #FundOralHealth
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Happy to see our new department website going live! 🎆 dental.buffalo.edu/departmen…

Oral Biology

As the first and oldest department of oral biology in a U.S. dental school and the first department to offer a PhD in oral biology, we proudly uphold a legacy of excellence that spans decades. The...

dental.buffalo.edu
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Stefan Ruhl@Ruhl_Lab
12 Oct 2025
academic.oup.com/gbe/article… 🦷🦷 #TEETH 🥛🥛 #MILK 💧💧 #SALIVA❗️
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🦷🦷 #TEETH❗️🦷🦷
Tied2Teeth@Tied2Teeth
7 Oct 2025
Replying to @Tied2Teeth
From shredders to slicers, from mower to spears… Dinosaur dental diversity mirrored their diets and niches; this adaptability in feeding strategies was likely a major key to their 200 million years of evolutionary success. Credit Image: commons.wikimedia.org/wiki/F…
Picture of phylogeny of main dinosaurs groups.

ALT Picture of phylogeny of main dinosaurs groups.

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Stefan Ruhl@Ruhl_Lab
27 Sep 2025
What have 🦷🦷 #TEETH 🦷🦷, 🥛🥛 #MILK 🥛🥛, and💧💧 #SALIVA 💧💧to do with each other? Ask @PetarPajic93 , Luane Landau, and @GokcumenLab ❗️ academic.oup.com/gbe/article…

Saliva Protein Genes in Humans were Shaped During Primate Evolution

Abstract. Genes within the secretory calcium-binding phosphoprotein locus diversified along with the formation of a calcified skeleton in vertebrates, the

academic.oup.com
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Stefan Ruhl retweeted
Petar Pajic@PetarPajic93
26 Sep 2025
Link to the paper to read more: doi.org/10.1093/gbe/evaf165 Special thanks to Omer Gokcumen @GokcumenLab and Stefan Ruhl @Ruhl_Lab !

Saliva Protein Genes in Humans were Shaped During Primate Evolution

Abstract. Genes within the secretory calcium-binding phosphoprotein locus diversified along with the formation of a calcified skeleton in vertebrates, the

academic.oup.com
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Stefan Ruhl@Ruhl_Lab
12 Sep 2025
🦷🦷 #TEETH ❗️🦷🦷
PNASNews@PNASNews
11 Sep 2025
The Spotted Ratfish, Hydrolagus colliei, is one of a group of fishes called chimaeras whose males sport a unique facial feature: the tenaculum, a club-shaped, cartilaginous appendage covered in teeth. A study investigates these extraoral teeth. In PNAS: ow.ly/pEXn50WVhJJ
Photograph of adult, male H. colliei in Puget Sound. (C) Micro-CT scan of male H. colliei. (G) Segmentation of the adult tenaculum. CREDIT: Photograph used with permission from Tiare Boyes.

ALT Photograph of adult, male H. colliei in Puget Sound. (C) Micro-CT scan of male H. colliei. (G) Segmentation of the adult tenaculum. CREDIT: Photograph used with permission from Tiare Boyes.

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🦷🦷 #TEETH ❗️🦷🦷
nature
@Nature
3 Sep 2025
Genetic-sequencing techniques have uncovered the oldest host-associated microbial DNA ever recorded — inside samples of teeth and bones from woolly and steppe mammoths. go.nature.com/424UwtE
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🦷🦷 #TEETH ❗️🦷🦷
Gareth Fraser@garethjfraser
2 Sep 2025
Ever wondered how #sharks produce an unlimited supply of teeth? Our new preprint uncovers the genes within the dental stem cell niche driving lifelong tooth development. "Shark tooth regeneration: RNAseq reveals genes for unlimited dental renewal" 🦈🦷 bit.ly/47kkRHL
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Stefan Ruhl retweeted
Ann Gibbons@evolutionscribe
27 Aug 2025
Another gift from Neanderthals and Denisovans: DNA from ancient bones reveals how Indigenous Americans got their mucus | Science | AAAS science.org/content/article/…

DNA from ancient bones reveals how Indigenous Americans got their mucus

Neanderthals and Denisovans passed along gene that provides a sticky shield against germs

science.org
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Stefan Ruhl retweeted
John Hawks
@johnhawks
23 Aug 2025
Published this week was one of the best evolutionary stories I’ve seen in a while. In a game of “genetic telephone” a 72-kb chunk of Denisovan DNA introgressed to Neanderthals, then slid into modern humans. And it makes mucus. johnhawks.net/p/the-gene-fro…

The gene from Denisovan to Neanderthal to modern mucus

A “genetic sandwich” reveals how a block of DNA entered several populations successively and was affected by natural selection.

johnhawks.net
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Stefan Ruhl@Ruhl_Lab
18 Jan 2025
Dear Friends, Colleagues, and Followers, I have reached a stage where I decided to take a break from the Twitter/X media platform. I will reconsider my decision after an extended period of time, but if I don't miss anything by then, I will cancel my account. // Stefan
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Stefan Ruhl retweeted
Massilani Lab@Diyendo
10 Jan 2025
Our Cell Genomics preview “Double or Nothing – Ancient Duplications in the Amylase Locus Drove Human Adaptation” covering Yilmaz F. (@feyza__yilmaz) et al., Science 2024 and Bolognini D. (@davidebolo93) et al., Nature 2024 is now out. massilani-lab.com/new-public…
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Stefan Ruhl@Ruhl_Lab
15 Nov 2024
🦷🦷 #TEETH 🦷🦷‼️ Why do humans mature so slowly? An ancient youth offers clues | Science | AAAS science.org/content/article/…

Why do humans mature so slowly? An ancient youth offers clues

Small-brained member of Homo that lived 1.8 million years ago may signal a step toward long, drawn-out childhoods

science.org
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🦷🦷 #TEETH 🦷🦷
John Hawks
@johnhawks
8 Nov 2024
The most substantial skeleton attributed to Homo habilis, extremely fragmented, is OH 62—around 1.8 million years old from the FLK site at Olduvai Gorge. Two teeth have grooves reflecting the individual's habitual use of toothpicks, among the oldest known. #FossilFriday
Two teeth from the OH 62 partial skeleton, both showing grooves made from toothpick use. Photo from Estalrrich et al. 2020

ALT Two teeth from the OH 62 partial skeleton, both showing grooves made from toothpick use. Photo from Estalrrich et al. 2020

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🦷🦷 #TEETH ❕🦷🦷
Sharlene Santana@SESantanaM
31 Oct 2024
In the past ~20 years, #microCT scanning has truly revolutionized the way we study #bat morphology and biomechanics. Check out what our lab has been up to recently in this interview @vaibhchhaya and I did for @Micro_Photonics: microphotonics.com/utilizing…
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Stefan Ruhl retweeted
Ann Gibbons@evolutionscribe
18 Oct 2024
Sugars to feed the brain? If these dates are correct, humans were able to digest more sugars in starch when our ancestors' brains went through a significant expansion: How humans evolved a starch-digesting superpower long before farming | Science | AAAS science.org/content/article/…

How humans evolved a starch-digesting superpower long before farming

Two papers show how agriculture drove gene to duplicate again and again, confirming and extending earlier studies

science.org
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