Joined February 2019
- Tweets 304
- Following 853
- Followers 1,569
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56 Photos and videos
Pinned Tweet
6 Feb 2023
Curious about the open questions in the field of liquid-liquid phase separation? Check out our latest paper in Communications Chemistry for a discussion of current insights and open questions. Read here: nature.com/articles/s42004-0…
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Still looking 👀 for a suitable candidate. Please retweet
📢 Open PhD position as part of #MSCA network of 17 students
@ComeInCell
Interested in exploring membrane stability/repair & #condensates ?
Check out & apply:
👉bit.ly/4fd8HRU
The project will include secondments at
@SaricLab, @MarquesLab & @NatureComms
ALT https://doi.org/10.1038/s41586-023-06726-w
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29 Dec 2024
Curious how biocondensates localize ions? We found that condensates selectively bind and localize both chaotropic anions and kosmotropic cations. This
alters the condensate composition, interface potential and RNA duplex stability inside. By @IrisSmokers
biorxiv.org/content/10.1101/…
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SpruijtLab retweeted
26 Dec 2024
Selective ion binding and uptake shape the microenvironment of biomolecular condensates
doi.org/10.1101/2024.12.24.6…
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19 Nov 2024
We are #hiring! For more information about our 17 #PhDposition and our #membrane and #membranecondensate projects , please check our website comeincell.org/projects/
1 Nov 2024
🚀 Exciting News! Today marks the official launch of the ComeInCell MSCA Doctoral Network! 🎉 Join us as we embark on a journey to advance cellular research and innovation.
Check the press release: mpikg.mpg.de/6845600/launch-…
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21 Nov 2024
We're thrilled to announce an open PhD position on exploring controlling condensate membrane attachment and exocytosis! Collaborate across Europe in the ComeInCell EU network. Apply now! Details: comeincell.org/ & ru.nl/en/working-at/job-oppo…
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3 Nov 2024
Ever wondered when coacervates appeared on early Earth and what they looked like? Think no more and have a look at our new preprint! Incredibly proud of @karinakinuyo and @mihoubi_nina for their incredible work, dedication and patience! 🤩
chemrxiv.org/engage/chemrxiv…
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30 Oct 2024
#ChemSystemsChem Phase-separated Droplets Can Direct the Kinetics of Chemical Reactions Including Polymerization, Self-replication and Oscillating Networks (Evan Spruijt and co-workers) #openaccess onlinelibrary.wiley.com/doi/…
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23 Oct 2024
Our latest preprint is now live on bioRxiv! We demonstrate how to control α-synuclein adsorption, desorption, and aggregation at charged biomolecular condensate interfaces. Check it out here: doi.org/10.1101/2024.10.20.6…
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30 Sep 2024
Check out a new @NaturePortfolio article collection on Liquid–liquid phase separation in cells.
nature.com/collections/iabce…
As part of the many great articles, you will find a Review from the @SpruijtLab published recently in Nat. Rev. Chem.
nature.com/articles/s41570-0…
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15 Aug 2024
Want to measure the volume fraction of biocondensates or coacervates?
We present easy and accurate methods, with which we found that upon destabilization, condensates can either shrink or swell, giving insight in condensate volume regulation in cells.
chemrxiv.org/engage/chemrxiv…
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12 Aug 2024
The role of biomolecular condensates in protein aggregation
nature.com/articles/s41570-0…
A review by Brent Visser, Wojciech Lipiński & Evan Spruijt from @SpruijtLab @Radboud_Uni
ALT The graphical abstract from the article highlighting the various effects that can affect liquid to solid transitions.
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12 Aug 2024
We are thrilled to announce that our latest review on the role of biomolecular condensates in protein aggregation is now published in @NatRevChem! Many thanks to the reviewers for their valuable suggestions and feedback. Open access here: nature.com/articles/s41570-0…
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6 Jul 2024
Coacervates can accelerate (bio)chemical reactions and direct their outcome. In our new review by @IrisSmokers we detail how their unique properties allow them to function as catalytic microcompartments at the origins of life. Have a look here:
pubs.acs.org/doi/10.1021/acs…
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5 Jul 2024
How Droplets Can Accelerate Reactions─Coacervate Protocells as Catalytic Microcompartments dlvr.it/T9Cx6J
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28 Jun 2024
In our new paper, now published in @Nature, we report on the discovery and implementation of a chemical reservoir computer based on the prebiotic formose reaction.
Congrats to Mathieu, Thijs, @quentin_duez , @robn_will and Wilhelm!🥳
Read the paper 👇
nature.com/articles/s41586-0…
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26 May 2024
The Many-Chemicals Problem of Systems Chemistry by Oliver R. Maguire @oliver_maguire onlinelibrary.wiley.com/doi/…
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6 Jun 2024
Exciting lab news! How can machine learning help us understand and predict #biomolecular #condensates? Thrilled to start my postdoc in @ProteinMagnus lab with this perspective led by Maria (@mcd_611) in @JMolBiol. Check it out! sciencedirect.com/science/ar…
#Biophysics #MolBiol #LLPS
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SpruijtLab retweeted
28 May 2024
An E. coli cell contains ~2500 different chemicals. A chemist combining 2500 different chemicals in a lab will result in an explosion. This is the Many-Chemicals Problem of Systems Chemistry. I explain how to overcome this key obstacle to creating more complex systems.
26 May 2024
The Many-Chemicals Problem of Systems Chemistry by Oliver R. Maguire @oliver_maguire onlinelibrary.wiley.com/doi/…
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29 Apr 2024
Over the weekend our publication on studying the surface charge of condensates on a single droplet level was published in @NatureComms! You can read it now here: doi.org/10.1038/s41467-024-4…
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23 Apr 2024
How do coacervates direct the outcome of (bio)chemical reactions? We developed a model to predict their effect on bimolecular, polymerization, self-replication and oscillating reactions, to guide experiments. Exciting results for origins of life & biology!
chemrxiv.org/engage/chemrxiv…
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23 Apr 2024
For oscillating reaction networks the periodicity and amplitude of oscillations can be altered by incorporation in a two-phase system, and oscillations can even be ‘rescued’ in concentration regimes where sustained oscillations do not take place in a single-phase system.
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