Organic chemistry lab interested in reaction development, total synthesis, chemical biology, and drug discovery
Joined April 2016
- Tweets 631
- Following 613
- Followers 4,117
- Likes 2,574
238 Photos and videos
Jun 12
Our lab recently discussed the career of our good friend David Nagib @nagiblab. What’s your favorite paper from Nagib? Here are some papers selected by us:
pubs.acs.org/doi/10.1021/jac…
nature.com/articles/nature10…
pubs.acs.org/doi/10.1021/ja9…
pubs.rsc.org/en/content/arti…
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Jun 11
Our lab recently discussed the research career of Veronique Gouverneur. What’s your favorite paper from the Gouverneur Lab? Here are some papers selected by us:
doi.org/10.1021/jacs.3c01303
science.org/doi/10.1126/scie…
pubs.rsc.org/en/content/arti…
science.org/doi/10.1126/scie…
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May 30
We’re hiring a biology postdoc in the Tambar Lab at UT Southwestern!
Interested in chemical biology, protein-small molecule interactions, target engagement, and targeted protein degradation? We’d love to hear from you.
PhD required. @utswpda
Apply here:
apply.interfolio.com/187301
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TambarLab retweeted
May 28
Our work on direct and redox-neutral C–H functionalization of pyridines with nucleophiles @J_A_C_S @ACSPublications Congratulations @BARALNILOFAR #NPDF @Pinku_Saikia25 @Devendr57748399 and Sabir pubs.acs.org/doi/10.1021/jac…
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Feb 12
Our lab recently discussed the research career of our good friend Neil Garg @GargLab @uclachem @UCLA. What’s your favorite paper from the Garg Lab? Here are some papers selected by us:
pubs.acs.org/doi/10.1021/ja0…
pubs.acs.org/doi/full/10.102…
nature.com/articles/nchem.23…
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Feb 11
Check out this cool cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides, which was recently reported by Honggen Wang and Qingjiang Li. Do you know the mechanism?
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Feb 9
Check out our review in @JournalCancer on recent advances in targeting HIF‐2 in renal cell carcinoma, with a focus on belzutifan. Academic labs can have a tangible impact on the treatment of cancer patients. @AmericanCancer @utswcancer @UTSWMedCenter
acsjournals.onlinelibrary.wi…
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Feb 7
Check out our recent paper in @ChemCatalysis on the photocatalytic three-component carbonyl alkylative amination. This reaction couples aldehydes, anilines, and alkyl arenes via direct C–H functionalization.
cell.com/chem-catalysis/abst…
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30 Dec 2025
Happy Holidays and Happy New Year from the Tambar Lab! Enjoy our Famous Chemists of the Week from 2025!
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29 Dec 2025
Happy Holidays and Happy New Year from the Tambar Lab! Enjoy our Mechanism Problems from 2025!
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23 Dec 2025
Our lab discussed the impactful research of Seth Herzon @HerzonLab @YaleChem. What’s your favorite Herzon paper? Here are some papers selected by our lab:
pubs.acs.org/doi/10.1021/ja9…
pubs.acs.org/doi/10.1021/jo4…
pubs.acs.org/doi/10.1021/jac…
science.org/doi/10.1126/scie…
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18 Dec 2025
Xihe Bi from Northeast Normal University reported this beautiful cyclization of 4-ynamides into dihydrofuran-2(3H)-ones What’s the mechanism? Mechanism by grad student Lauren Duncan.
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17 Dec 2025
Professor Karen Erickson @ClarkUniversity reported a beautiful rearrangement of (halomethylene)cycloalkanes. Let us know if you have any ideas for this insane mechanism! And let us know if you have a picture of Professor Erickson. Mechanism by grad student Rene Garcia Del Valle.
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16 Dec 2025
Happy birthday to grad students Thor Peterson and Jordan Martinez!
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17 Nov 2025
Lorena Saelices, Ph.D., and Uttam Tambar, Ph.D., are this year’s Biotech at Pegasus Park Milestone Award recipients for advancing an early preeclampsia test and a new therapy for drug-resistant prostate cancer. Learn more: bit.ly/482Gr2b #ScienceInAction #Biotech
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TambarLab retweeted
9 Dec 2025
Congratulations to our 2019 #HackermanAwardee @UttamTambar for winning a @UTSWMedCenter Milestone Award! The @TambarLab demonstrates how targeted glucocorticoid receptor (GR) degraders combats metastatic prostate cancer by eliminating drug-resistant proteins. tinyurl.com/4xtudej9
17 Nov 2025
Lorena Saelices, Ph.D., and Uttam Tambar, Ph.D., are this year’s Biotech at Pegasus Park Milestone Award recipients for advancing an early preeclampsia test and a new therapy for drug-resistant prostate cancer. Learn more: bit.ly/482Gr2b #ScienceInAction #Biotech
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8 Dec 2025
Our lab recently discussed the impactful research of Stephen Buchwald @ChemistryMIT. What’s your favorite Buchwald paper? Here are some papers selected by our lab:
onlinelibrary.wiley.com/doi/…
pubs.rsc.org/en/content/arti…
pubs.acs.org/doi/10.1021/ja1…
science.org/doi/10.1126/scie…
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TambarLab retweeted
6 Dec 2025
TexSyn-VII will be held May 29-30, 2026 at UT Dallas. Come see great synthetic chemistry from the Lone Star State, y’all! texsyn.org/
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20 Nov 2025
Thank you MilliporeSigma @MilliporeSigma for sponsoring another successful Aldrich-UTSW Excellence in Chemistry Symposium! We heard great seminars from Dean Toste @UCBerkeley, Mike Taylor @uarizona, Andrew Morrow (Smith Lab), and Nate Schmitt (Tambar Lab) @callmefortuNate
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