It's a busy week in the Herzon Lab as we celebrate another successful Ph.D. defense, this time by Dr. Alexandria Palazzo! Check out some of her recent work here: pubs.acs.org/doi/abs/10.1021…
Congratulations to our very own Dr. Vaani Gupta for her successful PhD defense! She has worked on a number of projects, including our recent synthesis and biological evaluation of (–)-gukulenin A!
Read more about her work here: science.org/doi/10.1126/scie…science.org/doi/10.1126/scie…
Nice story about our GBM research by Yale Student Isabella Backman. There are few treatment options for these patients, and none are curative. We are rooting for Merck and Company and hope they'll be able to get these drugs into the clinic soon!
medicine.yale.edu/news-artic…
Researchers at @Yale, including Camille Dreyfus Teacher-Scholars Seth Herzon (@HerzonLab) and Jason Crawford, "have synthesized a complex, potentially cancer-fighting molecule found in sea sponges discovered off the coast of South Korea."
news.yale.edu/2025/11/13/soa…
Congratulations to our very own Dr. Zechun Wang for his successful PhD defense! In his time with us, he has worked on a multitude of projects, including our recent synthesis and biological evaluation of (–)-gukulenin A!
Read about it here: science.org/doi/10.1126/scie…
Three-component assembly and structure–function relationships of (–)-gukulenin A by Vaani Gupta, Zechun Wang, Joshua B. Combs, Timothy Wright, Lei Chen, Boxu Lin, Ryan Holmes, Bo Qin, Joonseok Oh, Jason M. Crawford, and Seth B. Herzon @HerzonLab at @YaleChem in @ScienceMagazinescience.org/doi/10.1126/scie…
Out now in Science: Three-component assembly and structure–function relationships of (–)-gukulenin A, as a first release research article.
Congrats to the team! (1/4)
science.org/doi/10.1126/scie…
Absolutely beautiful !@MartinTomanik your team beats everyone in using these two bifunctional pyridone ligands for CH hydroxylation. The sp2 CH sp3 coupling with epoxide by MPAA ligand will also inspire more use of such sp2 Sp3 coupling. congrats ! @HerzonLab you trained him well
The total synthesis of chartelline C!
Accomplished in a small number of transformations from material intercepted en route to the securamines. Each step was informed by the unique topology and unconventional reactivity of these isolates 🥳🙌
pubs.acs.org/doi/10.1021/jac…
The Division of Organic Chemistry (DOC) congratulates the sixteen 2025 DOC Summer Undergraduate Research Fellowship (SURF) awardees and gratefully acknowledges the generous sponsors.
zurl.co/x1kZh
Prof. Seth Herzon accepting the @AmerChemSociety Award for Creative Work in Synthetic Organic Chemistry at the 2025 American Chemical Society meeting in San Diego. The group is proud to accept this honor!
Photo credits: EPNAC.com
This new piece showcases 100 natural products. Many of their syntheses have had significant impacts in org synth.
There are many different structural and functional motifs that have required amazing innovations in synthesis. And one of mine is in there too! #chemtwitter#sciart