Exciting science at the #EMBLProtein meeting, and still one more day ahead! If you missed it, come today by my poster 130 to learn about our work at Nedialkova's @MPI_Biochem and @gagneurlab! @EMBLEvents

SDR-seq is a droplet-based single-cell DNA-RNA sequencing platform for studying gene expression profiles linked to both noncoding and coding variants. @DLindenhofer @LarsMSteinmetz @embl nature.com/articles/s41592-0…

Really excited to see this out! 🤩 Congratulations to the team!

EMBL Researchers & their collaborators discovered a process by which cells prevent the activation of ancient viral sequences in the genome. The study shows experimentally, for the first time, the causal role certain histone sites play in gene repression. embl.org/news/science-techno…

Thrilled to share that our work from the Noh Lab @embl is now published in its peer-reviewed form @NatureComms! 🥳🥳🥳 Curious how histone H3.3 K9 and K27 residues contribute to transcriptional regulation? Here's a sneak peek...🧵 (1/n) 📄rdcu.be/dSyQz #chromatin

And that's a wrap! The Transcription and Chromatin Conference #EMBLTranscript here at @EMBL never fails to deliver. Truly inspiring talks and posters. Felt lucky to share and discuss our work with peers. Big thanks to the organizers @EMBLEvents !

Kyung Min Noh, an EMBL Group Leader from South Korea, has been awarded a DKK 20 million grant by the Novo Nordisk Foundation. Over the next seven years, Professor Noh will lead groundbreaking research at Aarhus University's Department of Biomedicine, focusing on chromatin mechanisms in neurodevelopment and disease. Neurodevelopmental and neuropsychiatric diseases like schizophrenia and major depressive disorder impact millions globally. Professor Noh’s research aims to uncover the chromatin mechanisms regulating neurodevelopment, potentially leading to innovative treatments and better patient outcomes. This grant is part of the Foundation’s Research Leader Programme, which recently awarded DKK 427 million to 41 researchers. We are proud to support Professor Noh's pioneering work and look forward to the advancements it will bring. Read more: researchleaderprogramme.com/…

On this day, 50 years ago, EMBL was established! Today, we celebrate five decades of EMBL, fuelled by infinite curiosity. EMBL turns 50, and we’d like to extend a huge thank you to everyone who contributed to reaching this milestone! #EMBL50

CRISPR has the potential to cure many genetic diseases, but it’s notoriously hard to use in neurons. In this work we tackled 2 of the main hurdles: Cas9 delivery and DNA repair. And we discovered… The rules of genome editing are different in neurons👇🏾 biorxiv.org/content/10.1101/…

Berlin Stem Cell Club is on 11 Jan at 16:15 - please join on-site or via Zoom the excellent talks by Kyung-Min Noh @embl and Daria Bunina @MDC_Berlin. Info here bit.ly/GSCNBSCC. #stemcells #stammzellen #chromatin #research @TUBerlin @BIMSB_MDC @mpi_ie @berlinnovation

Happy to see our new preprint out 🥳🥳. In this project we have analyzed how developmental genes can contribute to strengthen the insulation of their own regulatory domains. We hope you enjoy the reading! @RadaIglesiasLab @generegulation @thais_ealo

Seeking a cost-effective, scalable single-cell multiomic sequencing method? 🔍🧬 Meet SUM-seq: ATAC RNA in single nuclei! Check the latest preprint from Noh and @zauggj groups @embl! Huge congrats to @sara_lobmor, @umut_yildiz12, @AnniqueC, @MikaelMarttinen, and all authors! 🎉

Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage ... biorxiv.org/cgi/content/shor… #biorxiv_genomic

Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease biorxiv.org/cgi/content/shor… #bioRxiv

Happy to see the SUM-seq preprint out - our approach for scalable droplet-based single-cell ATAC RNA (up to 1M cells, hundreds of samples)! 🧬 biorxiv.org/content/10.1101/…

Interested to do scATAC-seq for your projects? Consider joining the course we are organizing with the Zaugg group at EMBL! Both practical and computational hands-on work and lectures about sample prep, the newest methods, and cool applications! 🧬 🧫 🥼 ✨

We are looking for a #PhD candidate! Are you interested in #chromatin and want to combine high-throughput methods & molecular biology to understand how histone #PTMs regulate chromatin functions using #yeast? 👩‍🔬🧑‍🔬🧫🧬 Contact us 👇Please spread the word!

simultaneous #single_cell #HiC and #RNA_seq shows that widespread chromatin rewiring occurs before transcription activation during lineage specification ⁦@ScienceMagazine⁩ science.org/doi/10.1126/scie…