Some of the most underinvested areas in frontier biology that could accelerate civilizational progress:
- Cheap, large-scale DNA synthesis (writing entire chromosomes or full organisms)
- Real-time, non-destructive RNA sequencing in living cells
- Highly accurate AI-powered polygenic scores for complex traits (disease risk, cognition, longevity) → enabling full genome design
- Ultra-precise, multiplex genome editing (far beyond CRISPR) with minimal off-target effects, scalable across millions of cells
- Safe, efficient, tissue-specific in vivo delivery systems
- Safe and effective human germline engineering
- Accelerated clinical trials via testing on decedents (with consent)
- Next-gen human enhancement: muscle, cognition, mood — beyond GLP-1s
- Ectogenesis / artificial wombs
Who’s actually building in these areas? Drop names, companies, or researchers below 👇